GENE:SKAP2
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SKAP2 |
FullNmae | src kinase associated phosphoprotein 2 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:15687 |
EnsembleID | ENSG00000005020 |
Uniprot | O75563 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SKAP2 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
SKAP2 | GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0007165,GO:0008285,GO:0042113 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
SKAP2 | hsa:8935 | path:hsa05135 | Yersinia infection - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SKAP2 | FYN | 20005715 | interaction type | N/A | PSP |
SKAP2 | LYN | 20005715 | interaction type | N/A | PSP |
SKAP2 | TGFBR1 | 20005715 | interaction type | N/A | PSP |
SKAP2 | TGFBR1 | 15761153 18988627 20005715 | N/A | N/A | SignaLink |
SKAP2 | FYN | 18988627 20005715 20005715 21071413 9837776 9837776 | N/A | N/A | SignaLink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | SKAP2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
E2F4 | SKAP2 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
FOXP3 | SKAP2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
PRDM14 | SKAP2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | SKAP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000171CD1 | SKAP2 | 18362358 | rna interference,inhibition | array technology,quantitative reverse transcription pcr | miRSponge |
URS0000171CD1 | SKAP2 | 18362358 25416803 | mrna cleavage,inhibition | array technology,quantitative reverse transcription pcr | TarBase |
URS0000237AF9 | SKAP2 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00005651EE | SKAP2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00004CCA62 | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001F373E | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000FFC8B | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002D0FC3 | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001938D9 | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000023F8DA | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000122F23 | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000008A99 | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000753AD | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075B538 | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000043C1C3 | SKAP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PTK2B | SKAP2 | 25348397 | N/A | physical interaction | ComPPI |
LYN | SKAP2 | 14525934 25348397 9837776 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SRC | SKAP2 | 25348397 | N/A | physical interaction | ComPPI |
KHDRBS1 | SKAP2 | 25348397 | N/A | physical interaction | ComPPI |
SKAP1 | SKAP2 | 25348397 | N/A | physical interaction | ComPPI |
SKAP2 | FYB1 | 14525934 25348397 9671755 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD |
SKAP2 | PRAM1 | 25348397 | N/A | physical interaction,in vivo | ComPPI |
SKAP2 | FYN | 14525934 25348397 9837776 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SKAP2 | HCK | 14525934 25348397 9837776 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SKAP2 | FASLG | 19807924 24234451 25348397 | N/A | phage display,physical interaction | ComPPI,IntAct |
SKAP2 | GRB2 | 19380743 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
SKAP2 | APP | 25348397 | N/A | physical interaction | ComPPI |
SKAP2 | RGS3 | 25348397 | N/A | physical interaction | ComPPI |
SKAP2 | ABHD5 | 25348397 | N/A | physical interaction | ComPPI |
SKAP2 | FRMD1 | 25348397 | N/A | physical interaction | ComPPI |
SKAP2 | SNRPN | 25348397 | N/A | physical interaction | ComPPI |
SKAP2 | DNAJB6 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
SKAP2 | PTPN22 | 21719704 24234451 25348397 | dephosphorylation reaction,physical association | anti tag coimmunoprecipitation,x-ray crystallography,phosphatase assay | ComPPI,IntAct |
SKAP2 | SKAP2 | 14525934 9671755 | N/A | experimental interaction detection | HPRD |
SKAP2 | TGFBR1 | 14525934 15761153 | N/A | experimental interaction detection | HPRD |