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GENE：SKAP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SKAP2
FullNmae src kinase associated phosphoprotein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15687
EnsembleID ENSG00000005020
Uniprot O75563

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SKAP2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SKAP2 GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0007165,GO:0008285,GO:0042113

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SKAP2 hsa:8935 path:hsa05135 Yersinia infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SKAP2 FYN 20005715 interaction type N/A PSP
SKAP2 LYN 20005715 interaction type N/A PSP
SKAP2 TGFBR1 20005715 interaction type N/A PSP
SKAP2 TGFBR1 15761153 18988627 20005715 N/A N/A SignaLink
SKAP2 FYN 18988627 20005715 20005715 21071413 9837776 9837776 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR SKAP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SKAP2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 SKAP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 SKAP2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SKAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 SKAP2 18362358 rna interference,inhibition array technology,quantitative reverse transcription pcr miRSponge
URS0000171CD1 SKAP2 18362358 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS0000237AF9 SKAP2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE SKAP2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004CCA62 SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000FFC8B SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002D0FC3 SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001938D9 SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 SKAP2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PTK2B SKAP2 25348397 N/A physical interaction ComPPI
LYN SKAP2 14525934 25348397 9837776 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SRC SKAP2 25348397 N/A physical interaction ComPPI
KHDRBS1 SKAP2 25348397 N/A physical interaction ComPPI
SKAP1 SKAP2 25348397 N/A physical interaction ComPPI
SKAP2 FYB1 14525934 25348397 9671755 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SKAP2 PRAM1 25348397 N/A physical interaction,in vivo ComPPI
SKAP2 FYN 14525934 25348397 9837776 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SKAP2 HCK 14525934 25348397 9837776 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SKAP2 FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
SKAP2 GRB2 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SKAP2 APP 25348397 N/A physical interaction ComPPI
SKAP2 RGS3 25348397 N/A physical interaction ComPPI
SKAP2 ABHD5 25348397 N/A physical interaction ComPPI
SKAP2 FRMD1 25348397 N/A physical interaction ComPPI
SKAP2 SNRPN 25348397 N/A physical interaction ComPPI
SKAP2 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SKAP2 PTPN22 21719704 24234451 25348397 dephosphorylation reaction,physical association anti tag coimmunoprecipitation,x-ray crystallography,phosphatase assay ComPPI,IntAct
SKAP2 SKAP2 14525934 9671755 N/A experimental interaction detection HPRD
SKAP2 TGFBR1 14525934 15761153 N/A experimental interaction detection HPRD

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