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GENE：PLK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLK1
FullNmae polo like kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9077
EnsembleID ENSG00000166851
Uniprot P53350

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLK1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PLK1 mitotic_cd 33155931 Pharmacological inhibitors of G2 checkpoint members or genetic suppression of PLK1, PLK2, ATR, ATM, CHK1, and CHK2 can trigger DNA-damage-stimulated mitotic catastrophe. retulator signature
PLK1 ferroptosis 38841177 These findings indicate that FBXO45 plays a role in mitigating ferroptosis in DN through the regulation of the PLK1/GPX4/SOX2 pathway. retulator signature
PLK1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLK1 GO:0000070,GO:0000086,GO:0000086,GO:0000122,GO:0000132,GO:0000278,GO:0000278,GO:0000281,GO:0000287,GO:0000776,GO:0000776,GO:0000785,GO:0000795,GO:0000922,GO:0000922,GO:0000940,GO:0001578,GO:0004672,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005813,GO:0005814,GO:0005819,GO:0005829,GO:0005876,GO:0006468,GO:0006468,GO:0007052,GO:0007052,GO:0007062,GO:0007076,GO:0007077,GO:0007091,GO:0007094,GO:0007095,GO:0007098,GO:0007346,GO:0008017,GO:0010800,GO:0010997,GO:0015630,GO:0016321,GO:0016567,GO:0018105,GO:0019901,GO:0030071,GO:0030071,GO:0030496,GO:0031648,GO:0032436,GO:0032465,GO:0032465,GO:0034451,GO:0042802,GO:0043066,GO:0043393,GO:0045143,GO:0045184,GO:0045736,GO:0045862,GO:0048313,GO:0051081,GO:0051233,GO:0051443,GO:0051726,GO:0070194,GO:0071168,GO:0090435,GO:0097431,GO:0106310,GO:1900182,GO:1901673,GO:1901990,GO:1904668,GO:1904776,GO:1905784

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLK1 hsa:5347 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
PLK1 hsa:5347 path:hsa04110 Cell cycle - Homo sapiens (human)
PLK1 hsa:5347 path:hsa04114 Oocyte meiosis - Homo sapiens (human)
PLK1 hsa:5347 path:hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PLK1 TERF1 18625707 18931676 19270156 19622404 19686080 21818122 22433952 22634377 26192618 8127874 interaction type N/A ACSN
PLK1 TNKS 18625707 18931676 19270156 19622404 19686080 21818122 22433952 22634377 26192618 8127874 interaction type N/A ACSN
PLK1 FANCM 11073952 17596790 18931676 19270156 19622404 19686080 26192618 8127874 interaction type N/A ACSN
PLK1 WEE1 11073952 17596790 18931676 19270156 19622404 19686080 26192618 8127874 interaction type N/A ACSN
PLK1 APC2 11073952 17596790 18931676 19270156 19622404 19686080 26192618 8127874 interaction type N/A ACSN
PLK1 CDC20 11073952 17596790 18931676 19270156 19622404 19686080 26192618 8127874 interaction type N/A ACSN
CDK1 PLK1 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 26192618 7575488 9892021 interaction type N/A ACSN
PLK1 MYC 11073952 17596790 18931676 19270156 19622404 19686080 26192618 8127874 interaction type N/A ACSN
PLK1 PKMYT1 11073952 17596790 18931676 19270156 19622404 19686080 26192618 8127874 interaction type N/A ACSN
PLK1 PIN1 10037602 16118204 23180781 9499405 phosphorylation reaction,physical association gst pull down,pull down,protein kinase assay InnateDB
PLK1 TSC1 16339216 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 PLK1 16339216 23180781 physical association anti tag coimmunoprecipitation InnateDB
PLK1 MAVS 19546225 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
IKBKB PLK1 18957422 23180781 phosphorylation reaction protein kinase assay InnateDB
PHC2 PLK1 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
OFD1 PLK1 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
PLK1 TANK 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP PLK1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 PLK1 17531812 17981789 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PLK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PLK1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PLK1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 PLK1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PLK1 24076372 trascriptional regulation,stimulation inferred by curator TFlink
E2F3 PLK1 16909110 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PLK1 24076372 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A405B PLK1 19739117 22120675 \N rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001A405B PLK1 19739117 21636267 22120675 22249248 23151088 23842624 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000338542 PLK1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000070B1D PLK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000036AFF1 PLK1 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS00001DA458 PLK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 PLK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 PLK1 23125021 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000435A77 PLK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 PLK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000FC8EB PLK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 PLK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 PLK1 25416803 26549165 26701625 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS00002E177F PLK1 25416803 27498003 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000055128B PLK1 25416803 27160062 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000096022 PLK1 25416803 25970317 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr TarBase
URS000000B1C9 PLK1 25416803 25970317 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr TarBase
URS0000345DEB PLK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 PLK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D1FC PLK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000011A030 PLK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000017EA6A PLK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005CCD18 PLK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005194EC PLK1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKA PLK1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPKAPK2 PLK1 22135298 phosphorylation N/A PhosphoSite
ABL1 PLK1 22135298 phosphorylation N/A PhosphoSite
PLK2 PLK1 22135298 phosphorylation N/A PhosphoSite
PLK1 DCTN1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 CCNT1 22135298 phosphorylation N/A PhosphoSite
PLK1 NINL 22135298 phosphorylation N/A PhosphoSite
PLK1 PTEN 22135298 phosphorylation N/A PhosphoSite
PLK1 CDC25B 22135298 phosphorylation N/A PhosphoSite
PLK1 PINX1 22135298 phosphorylation N/A PhosphoSite
PLK1 ANAPC1 22135298 phosphorylation N/A PhosphoSite
PLK1 IRS1 22135298 phosphorylation N/A PhosphoSite
PLK1 MAP9 22135298 phosphorylation N/A PhosphoSite
PLK1 PCNT 22135298 phosphorylation N/A PhosphoSite
PLK1 PRC1 22135298 phosphorylation N/A PhosphoSite
PLK1 CENPQ 22135298 phosphorylation N/A PhosphoSite
PLK1 KIF2C 22135298 phosphorylation N/A PhosphoSite
PLK1 KMT2E 22135298 phosphorylation N/A PhosphoSite
PLK1 MAD1L1 22135298 phosphorylation N/A PhosphoSite
PLK1 SUZ12 22135298 phosphorylation N/A PhosphoSite
PLK1 RIOK2 22135298 phosphorylation N/A PhosphoSite
PLK1 KIF2A 22135298 phosphorylation N/A PhosphoSite
PLK1 CDC27 22135298 phosphorylation N/A PhosphoSite
PLK1 BORA 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 OPTN 22135298 phosphorylation N/A PhosphoSite
PLK1 CLSPN 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 PIN1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 ESPL1 22135298 phosphorylation N/A PhosphoSite
PLK1 FBXO5 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 ANAPC7 22135298 phosphorylation N/A PhosphoSite
PLK1 RAP1GAP 22135298 phosphorylation N/A PhosphoSite
PLK1 BIRC5 22135298 phosphorylation N/A PhosphoSite
PLK1 IKBKB 22135298 phosphorylation N/A PhosphoSite
PLK1 GTSE1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 TOP2A 22135298 phosphorylation N/A PhosphoSite
PLK1 ZMYM2 22135298 phosphorylation N/A PhosphoSite
PLK1 NEDD1 22135298 phosphorylation N/A PhosphoSite
PLK1 CDC16 22135298 phosphorylation N/A PhosphoSite
PLK1 PTPN1 22135298 phosphorylation N/A PhosphoSite
PLK1 KIF2B 22135298 phosphorylation N/A PhosphoSite
PLK1 USP16 22135298 phosphorylation N/A PhosphoSite
PLK1 DVL2 22135298 phosphorylation N/A PhosphoSite
PLK1 PLEKHG6 22135298 phosphorylation N/A PhosphoSite
PLK1 MDM2 22135298 phosphorylation N/A PhosphoSite
PLK1 PRKN 22135298 phosphorylation N/A PhosphoSite
PLK1 HNRNPU 22135298 phosphorylation N/A PhosphoSite
PLK1 TOPORS 22135298 phosphorylation N/A PhosphoSite
PLK1 CTNNB1 22135298 phosphorylation N/A PhosphoSite
PLK1 NPM1 22135298 phosphorylation N/A PhosphoSite
PLK1 FADD 22135298 phosphorylation N/A PhosphoSite
PLK1 BRCA1 22135298 phosphorylation N/A PhosphoSite
PLK1 CDC25C 22135298 phosphorylation N/A PhosphoSite
PLK1 GORASP1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 BRCA2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 LRRK1 22135298 phosphorylation N/A PhosphoSite
PLK1 ATXN10 22135298 phosphorylation N/A PhosphoSite
PLK1 RACGAP1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 KAT7 22135298 phosphorylation N/A PhosphoSite
PLK1 CLIP1 22135298 phosphorylation N/A PhosphoSite
PLK1 PPP1R7 22135298 phosphorylation N/A PhosphoSite
PLK1 STIL 22135298 phosphorylation N/A PhosphoSite
PLK1 ANAPC4 22135298 phosphorylation N/A PhosphoSite
PLK1 BUB1B 22135298 phosphorylation N/A PhosphoSite
PLK1 CCNB1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 CENPU 22135298 phosphorylation N/A PhosphoSite
PLK1 FOXM1 22135298 phosphorylation N/A PhosphoSite
PLK1 MAP2K1 22135298 phosphorylation N/A PhosphoSite
PLK1 CDC6 22135298 phosphorylation N/A PhosphoSite
PLK1 NUDC 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 AXIN2 22135298 phosphorylation N/A PhosphoSite
PLK1 PKMYT1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 MYC 22135298 phosphorylation N/A PhosphoSite
PLK1 BRF1 22135298 phosphorylation N/A PhosphoSite
PLK1 YY1 22135298 phosphorylation N/A PhosphoSite
PLK1 CHEK2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 NUAK1 22135298 phosphorylation N/A PhosphoSite
PLK1 TP53BP1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 VIM 22135298 phosphorylation N/A PhosphoSite
PLK1 SVIL 22135298 phosphorylation N/A PhosphoSite
PLK1 CDC23 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 WEE1 22135298 phosphorylation N/A PhosphoSite
PLK1 KDM1A 22135298 phosphorylation N/A PhosphoSite
PLK1 RAN 22135298 phosphorylation N/A PhosphoSite
PLK1 SUGT1 22135298 phosphorylation N/A PhosphoSite
PLK1 TP73 22135298 phosphorylation N/A PhosphoSite
PLK1 RUVBL1 22135298 phosphorylation N/A PhosphoSite
PLK1 CEP55 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 HSF1 22135298 phosphorylation N/A PhosphoSite
PLK1 MAP2K2 22135298 phosphorylation N/A PhosphoSite
PLK1 SRI 22135298 phosphorylation N/A PhosphoSite
PLK1 BCL2L1 22135298 phosphorylation N/A PhosphoSite
PLK1 TERF1 22135298 phosphorylation N/A PhosphoSite
PLK1 ERCC6L 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PLK1 SNCB 22135298 phosphorylation N/A PhosphoSite
PLK1 KIZ 22135298 phosphorylation N/A PhosphoSite
PLK1 RAD51 22135298 phosphorylation N/A PhosphoSite
PLK1 TEX14 22135298 phosphorylation N/A PhosphoSite
PLK1 RSF1 22135298 phosphorylation N/A PhosphoSite
PLK1 SNCA 22135298 phosphorylation N/A PhosphoSite
PLK1 ORC2 22135298 phosphorylation N/A PhosphoSite
STK10 PLK1 22135298 phosphorylation N/A PhosphoSite
PAK1 PLK1 22135298 phosphorylation N/A PhosphoSite
MAP3K8 PLK1 22135298 phosphorylation N/A PhosphoSite
AURKB PLK1 22135298 phosphorylation N/A PhosphoSite
PLK1 AURKA 25361965 interaction type N/A PTMCode2
PIN1 PLK1 25361965 interaction type N/A PTMCode2
PLK1 BUB1 25361965 interaction type N/A PTMCode2
BUB1 PLK1 25361965 interaction type N/A PTMCode2
PLK1 MCM7 25361965 interaction type N/A PTMCode2
MCM7 PLK1 25361965 interaction type N/A PTMCode2
PLK1 CYLD 25361965 interaction type N/A PTMCode2
CYLD PLK1 25361965 interaction type N/A PTMCode2
RACGAP1 PLK1 25361965 interaction type N/A PTMCode2
CLSPN PLK1 25361965 interaction type N/A PTMCode2
GORASP1 PLK1 25361965 interaction type N/A PTMCode2
NUDC PLK1 25361965 interaction type N/A PTMCode2
PLK1 MYT1 25361965 interaction type N/A PTMCode2
MYT1 PLK1 25361965 interaction type N/A PTMCode2
ERCC6L PLK1 25361965 interaction type N/A PTMCode2
PLK1 SMC3 25361965 interaction type N/A PTMCode2
SMC3 PLK1 25361965 interaction type N/A PTMCode2
DCTN1 PLK1 25361965 interaction type N/A PTMCode2
PLK1 ASPM 25361965 interaction type N/A PTMCode2
ASPM PLK1 25361965 interaction type N/A PTMCode2
PLK1 EVI5 25361965 interaction type N/A PTMCode2
EVI5 PLK1 25361965 interaction type N/A PTMCode2
CEP55 PLK1 25361965 interaction type N/A PTMCode2
BRCA2 PLK1 25361965 interaction type N/A PTMCode2
TP53BP1 PLK1 25361965 interaction type N/A PTMCode2
CHEK2 PLK1 25361965 interaction type N/A PTMCode2
BORA PLK1 25361965 interaction type N/A PTMCode2
CDC23 PLK1 25361965 interaction type N/A PTMCode2
MCM2 PLK1 25361965 interaction type N/A PTMCode2
PLK1 MCM2 25361965 interaction type N/A PTMCode2
ECT2 PLK1 25361965 interaction type N/A PTMCode2
PLK1 ECT2 25361965 interaction type N/A PTMCode2
GTSE1 PLK1 25361965 interaction type N/A PTMCode2
PKMYT1 PLK1 25361965 interaction type N/A PTMCode2
FBXO5 PLK1 25361965 interaction type N/A PTMCode2
TP53 PLK1 25361965 interaction type N/A PTMCode2
PLK1 TP53 25361965 interaction type N/A PTMCode2
KIF23 PLK1 25361965 interaction type N/A PTMCode2
PLK1 KIF23 25361965 interaction type N/A PTMCode2
TSC1 PLK1 25361965 interaction type N/A PTMCode2
PLK1 TSC1 25361965 interaction type N/A PTMCode2
TUBG1 PLK1 25361965 interaction type N/A PTMCode2
PLK1 TUBG1 25361965 interaction type N/A PTMCode2
CCNB1 PLK1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 PLK1 14525934 16118204 25348397 9499405 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LMO4 PLK1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNW1 PLK1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L PLK1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USP20 PLK1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDC80 PLK1 25348397 N/A physical interaction ComPPI
MIS18A PLK1 24234451 25036634 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPP25L PLK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CEP43 PLK1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NPM1 PLK1 14525934 15190079 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
FABP3 PLK1 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LCA5 PLK1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TUBB PLK1 25348397 N/A in vitro,in vivo ComPPI
TP53BP1 PLK1 20126263 24234451 25348397 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,pull down,phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
VCP PLK1 25348397 N/A physical interaction ComPPI
FAM53C PLK1 25348397 N/A physical interaction ComPPI
TP53BP2 PLK1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MCM6 PLK1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
MCM2 PLK1 14525934 15654075 24234451 25348397 27173435 association,physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
PSMB2 PLK1 11205743 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PHC2 PLK1 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
DDX17 PLK1 25348397 N/A physical interaction ComPPI
BCL2L1 PLK1 25348397 N/A physical interaction ComPPI
SPAG5 PLK1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DRICH1 PLK1 25348397 N/A physical interaction ComPPI
PAK5 PLK1 25348397 N/A physical interaction ComPPI
EGLN3 PLK1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
RABAC1 PLK1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PAK1 PLK1 20869364 24234451 25348397 physical association pull down ComPPI,IntAct
ARHGAP5 PLK1 25348397 N/A physical interaction ComPPI
RACGAP1 PLK1 19468300 19468302 24234451 25348397 phosphorylation reaction,association anti bait coimmunoprecipitation,far western blotting,phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
MST1R PLK1 25348397 N/A physical interaction ComPPI
FBXW7 PLK1 25348397 N/A physical interaction ComPPI
NEDD9 PLK1 22609948 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
JUN PLK1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EP300 PLK1 21988832 24234451 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
COPS5 PLK1 25348397 N/A physical interaction ComPPI
CTBP1 PLK1 25348397 N/A physical interaction ComPPI
FZR1 PLK1 14734534 23160376 23972993 25348397 26387737 27898060 N/A physical interaction ComPPI,OmniPath
PSMA3 PLK1 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FEZ1 PLK1 25348397 N/A physical interaction ComPPI
PTHLH PLK1 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLU PLK1 25348397 N/A physical interaction ComPPI
MED1 PLK1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TUBG1 PLK1 10191277 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NTRK1 PLK1 25348397 N/A physical interaction ComPPI
PITPNA PLK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BTRC PLK1 24234451 25348397 25503564 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG6 PLK1 25348397 N/A physical interaction ComPPI
BUB1 PLK1 14525934 16760428 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
AXIN2 PLK1 16815967 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA1A PLK1 21887822 24234451 25348397 phosphorylation reaction,colocalization,physical association anti bait coimmunoprecipitation,protein kinase assay,confocal microscopy ComPPI,IntAct
HSPA1B PLK1 25348397 N/A protein kinase assay ComPPI
CDC6 PLK1 21041660 24234451 25348397 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,pull down,phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
PLK1 PSMA5 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK1 CEP55 14525934 16198290 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PLK1 TUBA4A 10191277 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PLK1 BRCA2 12815053 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PLK1 PSMB5 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK1 MYT1 12738781 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PLK1 PKMYT1 12738781 14525934 23397142 24234451 25348397 physical association experimental interaction detection,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
PLK1 MCM3 15654075 24234451 25348397 physical association coimmunoprecipitation,in vivo ComPPI,IntAct
PLK1 PSMA1 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK1 PSMA6 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK1 PSMB7 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK1 CHEK2 10973490 11901158 12024051 12242661 12493754 14525934 20126263 24234451 25348397 phosphorylation reaction,colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,phosphorylation reaction,physical interaction,fluorescence microscopy,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
PLK1 KIF23 14525934 25348397 8524282 N/A experimental interaction detection,in vivo ComPPI,HPRD
PLK1 PSMA7 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK1 GORASP1 11447294 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PLK1 ASPM 11283617 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PLK1 NUDC 12852857 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PLK1 PSMA4 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK1 TPT1 12167714 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PLK1 WEE1 14525934 15070733 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,kinase homogeneous time resolved fluorescence,in vitro ComPPI,HPRD,IntAct
PLK1 CCNB1 11242082 14525934 23397142 24234451 25348397 physical association experimental interaction detection,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
PLK1 ECT2 14525934 16247472 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PLK1 MAGED1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLK1 RECQL5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLK1 GET4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLK1 NINL 12852856 14525934 24234451 25348397 26638075 association experimental interaction detection,physical interaction,in vitro,proximity-dependent biotin identification ComPPI,HPRD,IntAct
PLK1 PRC1 14525934 17351640 19468300 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PLK1 TSC1 14525934 16339216 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK1 CTNNB1 14525934 19001871 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PLK1 BIRC6 14525934 18329369 24234451 25348397 26496610 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo ComPPI,HPRD,IntAct
PLK1 CDC25C 11202906 11897663 12595692 14525934 14532005 16753148 17307877 19597481 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,classical fluorescence spectroscopy,coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PLK1 MCM7 14525934 15654075 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
PLK1 DCTN1 25348397 N/A physical interaction ComPPI
PLK1 DNAJB9 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLK1 TSC2 25348397 N/A physical interaction ComPPI
PLK1 PSMA2 25348397 N/A physical interaction ComPPI
PLK1 PSMB6 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PLK1 BORA 18615013 19596235 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 SGO1 25348397 N/A physical interaction ComPPI
PLK1 CYLD 17495026 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PLK1 BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 SLX4 19596235 24234451 25348397 25852190 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PLK1 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 SPAG9 19596235 24234451 25348397 27173435 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 BICD2 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 ERCC6L 20360068 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PLK1 WDCP 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 PPP6R2 19596235 24234451 24255178 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 TMF1 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 BICD1 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 ANKRD44 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 OSBPL6 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 LPL 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 BTN1A1 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 CEP97 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 SRPX 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 ANKRD28 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 ANKRD52 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 SLX4IP 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 GTF3C3 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 RGPD4 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 ERCC4 19596235 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 CLSPN 25348397 N/A physical interaction ComPPI
PLK1 STK3 20562859 24234451 24255178 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 AURKA 18615013 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,protein kinase assay ComPPI,IntAct
PLK1 FBXO5 16439210 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
PLK1 TANK 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PLK1 IKBKG 25348397 N/A physical interaction ComPPI
PLK1 CHFR 25348397 N/A physical interaction ComPPI
PLK1 TOPORS 25348397 N/A physical interaction ComPPI
PLK1 RELA 25348397 N/A physical interaction ComPPI
PLK1 MYC 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PLK1 TNFSF11 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 ACTL6B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 CIC 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 RXRA 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 RNF126 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 LRP5L 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 CCDC115 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 FBXL5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 VRK3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 EIF6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 SPOUT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 MPP2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 ZNF71 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 GLB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 SIMC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 C6ORF136 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 INTS11 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 ITSN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 TUBA1A 25348397 N/A physical interaction ComPPI
PLK1 MC1R 25348397 N/A physical interaction ComPPI
PLK1 TUBB3 25348397 N/A physical interaction ComPPI
PLK1 NEDD4 25348397 N/A physical interaction ComPPI
PLK1 DNHD1 25348397 N/A physical interaction ComPPI
PLK1 CENPU 25348397 N/A isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction,physical interaction ComPPI
PLK1 CENPQ 25348397 N/A physical interaction ComPPI
PLK1 IKBKB 25348397 N/A physical interaction ComPPI
PLK1 TRIOBP 25348397 N/A physical interaction ComPPI
PLK1 CALML5 25348397 N/A physical interaction ComPPI
PLK1 HSF1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 PTPN14 25348397 N/A physical interaction ComPPI
PLK1 BUB1B 25348397 N/A physical interaction ComPPI
PLK1 CSN1S1 25348397 N/A physical interaction ComPPI
PLK1 MDM2 19833129 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,pull down,physical interaction,protein kinase assay ComPPI,IntAct
PLK1 TP53 14525934 16753148 19833129 22653443 24234451 25348397 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,protein kinase assay,two hybrid ComPPI,HPRD,IntAct
PLK1 USP37 25348397 N/A physical interaction ComPPI
PLK1 STAG2 25348397 N/A physical interaction ComPPI
PLK1 SNCA 25348397 N/A physical interaction ComPPI
PLK1 SNCB 25348397 N/A physical interaction ComPPI
PLK1 APP 25348397 N/A physical interaction ComPPI
PLK1 TP53I3 25348397 N/A physical interaction ComPPI
PLK1 CDC20 25348397 N/A physical interaction ComPPI
PLK1 HSPA4 25348397 N/A physical interaction ComPPI
PLK1 KLHL22 25348397 N/A physical interaction ComPPI
PLK1 KLHL21 25348397 N/A physical interaction ComPPI
PLK1 KLHL9 25348397 N/A physical interaction ComPPI
PLK1 CUL2 25348397 N/A physical interaction ComPPI
PLK1 SUGT1 25348397 N/A physical interaction ComPPI
PLK1 LATS1 25348397 N/A physical interaction ComPPI
PLK1 CDCA5 25348397 N/A physical interaction ComPPI
PLK1 OFD1 21988832 24234451 25348397 26638075 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 KRBA1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 FBXO6 25348397 N/A physical interaction ComPPI
PLK1 NUAK1 25348397 N/A physical interaction ComPPI
PLK1 EGFR 25348397 N/A physical interaction ComPPI
PLK1 BRCA1 24067368 24234451 25348397 25483079 27898060 29656893 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct,OmniPath
PLK1 RAP1GAP 25348397 N/A physical interaction ComPPI
PLK1 CDC14A 19390576 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PLK1 IFTAP 25348397 N/A physical interaction ComPPI
PLK1 TRAK2 25348397 N/A physical interaction ComPPI
PLK1 CACNG3 25348397 N/A physical interaction ComPPI
PLK1 LTBR 25348397 N/A physical interaction ComPPI
PLK1 CDC20B 25348397 N/A physical interaction ComPPI
PLK1 MIER2 25348397 N/A physical interaction ComPPI
PLK1 RAI14 25348397 N/A physical interaction ComPPI
PLK1 TOPBP1 25348397 N/A physical interaction ComPPI
PLK1 KAT8 25348397 N/A physical interaction ComPPI
PLK1 KIF2C 25348397 N/A physical interaction ComPPI
PLK1 REST 25348397 N/A physical interaction ComPPI
PLK1 SMC1A 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 RRM2 25348397 N/A physical interaction ComPPI
PLK1 SMC3 25348397 N/A physical interaction ComPPI
PLK1 PLK4 25348397 N/A physical interaction ComPPI
PLK1 CENPJ 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 PCM1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 CEP104 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 CEP162 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 CNTROB 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 CEP135 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 CNTRL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 FBF1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 NIN 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 ODF2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLK1 AHSA1 25348397 N/A physical interaction ComPPI
PLK1 ATP7A 25348397 N/A physical interaction ComPPI
PLK1 CIRBP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 DNM2 25348397 N/A physical interaction ComPPI
PLK1 DSC1 25348397 N/A physical interaction ComPPI
PLK1 DSG1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 MECP2 25348397 N/A physical interaction ComPPI
PLK1 NDUFA10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 RBBP8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 EVI5 16439210 24234451 25348397 26496610 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,physical interaction,protein kinase assay ComPPI,IntAct
PLK1 VAMP4 25348397 N/A physical interaction ComPPI
PLK1 EED 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 CHD1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 ORC3 25348397 N/A physical interaction ComPPI
PLK1 SACS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 DNAAF5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 HMCES 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 EPS15L1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 TUT7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 MRPL55 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 FOXO3 25348397 N/A physical interaction ComPPI
PLK1 USP16 25348397 N/A physical interaction ComPPI
PLK1 PRKN 25348397 N/A physical interaction ComPPI
PLK1 RICTOR 25348397 25714006 27898060 N/A physical interaction ComPPI,OmniPath
PLK1 MAPKAPK2 25348397 N/A physical interaction ComPPI
PLK1 TOP2A 25348397 N/A physical interaction ComPPI
PLK1 NFATC2 25348397 N/A physical interaction ComPPI
PLK1 PTEN 25348397 N/A anti bait coimmunoprecipitation,physical interaction,physical interaction ComPPI
PLK1 RGCC 25348397 N/A physical interaction ComPPI
PLK1 MTMR14 25348397 N/A physical interaction ComPPI
PLK1 MTMR3 25348397 N/A physical interaction ComPPI
PLK1 ZC3HC1 25348397 N/A physical interaction ComPPI
PLK1 C1ORF226 25348397 N/A physical interaction ComPPI
PLK1 MPRIP 25348397 N/A physical interaction ComPPI
PLK1 PRRC1 25348397 N/A physical interaction ComPPI
PLK1 MAVS 25348397 N/A physical interaction ComPPI
PLK1 NOS1AP 25348397 N/A physical interaction ComPPI
PLK1 STXBP4 25348397 N/A physical interaction ComPPI
PLK1 DCAF11 25348397 N/A physical interaction ComPPI
PLK1 RGS20 25348397 N/A physical interaction ComPPI
PLK1 TBK1 25348397 N/A physical interaction ComPPI
PLK1 SATB2 25348397 N/A physical interaction ComPPI
PLK1 FAM131B 25348397 N/A physical interaction ComPPI
PLK1 MAJIN 25348397 N/A physical interaction ComPPI
PLK1 HDAC2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 GTF3C5 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 CFAP20 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 SF3B3 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 USP15 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 MCM4 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 IVNS1ABP 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 GTF3C4 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 RFX3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PLK1 FOXJ1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 NEK7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PLK1 IFT43 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PLK1 DCAF7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PLK1 JADE1 25348397 N/A physical interaction ComPPI
PLK1 SREBF1 25348397 N/A physical interaction ComPPI
PLK1 TRIM25 25348397 N/A physical interaction ComPPI
PLK1 KAT7 18250300 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,far western blotting,physical interaction,protein kinase assay ComPPI,IntAct
PLK1 A1BG 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
PLK1 BLM 16864798 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PLK1 CEP68 24234451 25348397 25503564 phosphorylation reaction,physical association anti tag coimmunoprecipitation,phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
PLK1 LRRK1 24234451 25348397 26192437 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PLK1 RASGRF1 16753148 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PLK1 TOP3A 20360068 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PLK1 GTSE1 20577264 24234451 25348397 phosphorylation reaction,colocalization,physical association anti bait coimmunoprecipitation,fluorescence microscopy,protein kinase assay ComPPI,IntAct
PLK1 PAK3 20869364 24234451 25348397 physical association pull down ComPPI,IntAct
PLK1 CLIP1 20664522 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PLK1 ULK2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLK1 RB1CC1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLK1 DIXDC1 20823832 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PLK1 FADD 20890306 24234451 25348397 phosphorylation reaction,colocalization,physical association anti bait coimmunoprecipitation,molecular sieving,pull down,protein kinase assay,confocal microscopy,immunodepleted coimmunoprecipitation ComPPI,IntAct
PLK1 NEK9 21642957 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down ComPPI,IntAct
PLK1 CRELD2 21900206 24234451 25348397 physical association two hybrid ComPPI,IntAct
PLK1 RAD23B 21887822 24234451 25348397 phosphorylation reaction,colocalization protein kinase assay,confocal microscopy ComPPI,IntAct
PLK1 EIF4B 21887822 24234451 25348397 phosphorylation reaction,colocalization protein kinase assay,confocal microscopy ComPPI,IntAct
PLK1 DVL2 22609948 24234451 25348397 physical association pull down ComPPI,IntAct
PLK1 DCTN6 23455152 24234451 25348397 association pull down ComPPI,IntAct
PLK1 INCENP 21051298 24234451 25348397 physical association proximity ligation assay ComPPI,IntAct
PLK1 LRRK2 24234451 24510904 25348397 N/A protein array ComPPI,IntAct
PLK1 SSX2IP 24234451 24397932 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLK1 PTPRD 22305495 24234451 25348397 N/A protein array ComPPI,IntAct
MAPK6 PLK1 21900206 24234451 25348397 29426014 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PSMB4 PLK1 11205743 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PSMB1 PLK1 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PSMB3 PLK1 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PLK2 PLK1 19706541 24234451 25348397 phosphorylation reaction phosphorylation reaction,protein kinase assay ComPPI,IntAct
MUS81 PLK1 25348397 N/A physical interaction ComPPI
PPID PLK1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CSN2 PLK1 25348397 N/A physical interaction ComPPI
DCTPP1 PLK1 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 TUBB2A 10191277 14525934 N/A experimental interaction detection HPRD
PITPNM1 PLK1 14525934 15125835 N/A experimental interaction detection HPRD
PLK1 PLK1 14532005 21041660 23354166 24234451 26192437 phosphorylation reaction,physical association pull down,protein kinase assay IntAct
PLK1 MEIKIN 24234451 25533956 physical association two hybrid IntAct
PLK1 DDX39B 21637952 27898060 N/A N/A OmniPath
PLK1 TERF1 18625707 27898060 stimulant N/A OmniPath
PLK1 CTNNB1 19001871 21610149 27898060 N/A N/A OmniPath
PLK1 PCNT 22184200 24466316 27898060 N/A N/A OmniPath
PLK1 FANCM 19680264 27898060 inhibition N/A OmniPath
PLK1 TCF3 14592976 27898060 N/A N/A OmniPath
MAPKAPK2 PLK1 18695677 27898060 stimulant N/A OmniPath
PLK1 FBXO5 15148369 15469984 16439210 17875940 27898060 inhibition,stimulant N/A OmniPath
INCENP PLK1 19228686 21051298 27898060 stimulant N/A OmniPath
MAP3K8 PLK1 12207013 27898060 stimulant N/A OmniPath
PLK1 RAD21 18616427 27898060 stimulant N/A OmniPath
PLK1 HNRNPU 25986610 27898060 N/A N/A OmniPath
PLK1 CHEK2 10973490 11901158 12024051 12242661 12493754 20126263 27898060 inhibition,stimulant N/A OmniPath
PLK1 RAD51 26059434 27898060 N/A N/A OmniPath
PLK1 FADD 20890306 27898060 inhibition N/A OmniPath
PLK1 MAD1L1 18922800 27898060 N/A N/A OmniPath
PLK1 CDC25B 21640712 27898060 stimulant N/A OmniPath
PLK1 MYC 23887393 27898060 stimulant N/A OmniPath
PLK1 MDM2 12383858 19833129 27898060 stimulant N/A OmniPath
PLK1 PIN1 10037602 16118204 22926167 27898060 9499405 stimulant N/A OmniPath
PIN1 PLK1 10037602 16118204 27898060 9499405 N/A N/A OmniPath
ATR PLK1 12147700 27898060 inhibition N/A OmniPath
MAVS PLK1 19546225 27898060 N/A N/A OmniPath
PDPK1 PLK1 23887393 27898060 stimulant N/A OmniPath
ATM PLK1 12147700 27898060 inhibition N/A OmniPath
PLK1 CDC6 21041660 27898060 stimulant N/A OmniPath
PLK1 WEE1 15070733 15350223 16085715 18285803 27898060 inhibition,stimulant N/A OmniPath
PLK1 IRS1 12351658 15849359 20135346 27898060 inhibition N/A OmniPath
PLK1 CDC25C 11202906 11897663 12595692 14532005 14968113 16753148 17307877 18062778 19503101 19597481 27898060 stimulant N/A OmniPath
AURKA PLK1 12207013 18477460 18615013 18669648 18691976 18773538 19228686 19369195 22939629 27898060 stimulant N/A OmniPath
PLK1 RAC1 10617634 27898060 N/A N/A OmniPath
PLK1 RACGAP1 16565220 17081983 19007248 19468300 19468302 19690332 25486482 27898060 stimulant N/A OmniPath
PLK1 GORASP1 11447294 22523075 27898060 N/A N/A OmniPath
PLK1 SUZ12 25855382 27898060 N/A N/A OmniPath
BUB1 PLK1 16760428 19228686 27898060 stimulant N/A OmniPath
PLK1 TP53BP1 20126263 24703952 25607646 27898060 N/A N/A OmniPath
PLK1 CAMKK2 15209507 27898060 N/A N/A OmniPath
CHFR PLK1 11807090 16647857 19182791 27898060 inhibition N/A OmniPath
PLK1 HSF1 18794143 19934326 27898060 inhibition,stimulant N/A OmniPath
PLK1 BORA 18378770 18521620 18615013 19596235 24067368 26186194 27898060 inhibition,stimulant N/A OmniPath
BORA PLK1 18378770 18521620 18615013 19228686 19596235 24067368 26186194 27898060 stimulant N/A OmniPath
PLK1 ECT2 16247472 17332740 18669648 27898060 stimulant N/A OmniPath
PLK1 NPM1 15190079 19413330 19651622 20068231 20352051 27898060 stimulant N/A OmniPath
PLK1 SMC1A 11970886 27898060 inhibition,stimulant N/A OmniPath
PLK1 KAT7 17525332 18250300 18669648 19007248 19413330 19690332 27898060 stimulant N/A OmniPath
PLK1 TSC2 16339216 27898060 N/A N/A OmniPath
PAK1 PLK1 18427546 20869364 27898060 stimulant N/A OmniPath
PLK1 GTSE1 20577264 27898060 stimulant N/A OmniPath
PLK1 CCNB1 11242082 12447691 12524548 19364923 20117088 20126263 22726437 23397142 24101512 24582498 24910099 25362646 25849598 27898060 stimulant N/A OmniPath
PLK1 VIM 18056432 27898060 9794428 stimulant N/A OmniPath
PPP2CA PLK1 27898060 9344838 N/A N/A OmniPath
PLK1 BIRC5 21148584 27898060 stimulant N/A OmniPath
PLK1 RUVBL1 26201077 27898060 N/A N/A OmniPath
PLK1 PRC1 17351640 22621898 23940115 25512391 27898060 N/A N/A OmniPath
PLK1 STAG2 18616427 27898060 stimulant N/A OmniPath
PLK1 MAP9 20615875 27898060 stimulant N/A OmniPath
PLK1 YY1 21253604 23226345 27898060 stimulant N/A OmniPath
PLK1 TP73 18174154 18418051 25379016 27898060 inhibition,stimulant N/A OmniPath
PLK1 PKMYT1 12738781 18691976 23397142 27898060 inhibition N/A OmniPath
PLK1 CLSPN 15163406 16885021 16885022 27898060 inhibition,stimulant N/A OmniPath
PLK1 CAMKK1 10187789 27898060 N/A N/A OmniPath
PLK1 BUB1B 17376779 17785528 19228686 19503101 23079597 23455478 24067371 26323689 27898060 stimulant N/A OmniPath
PLK1 SNCA 10617630 10852916 11813001 12505616 14579119 14645218 15834418 15944382 16847063 16957079 16959772 17296554 17652097 18178617 18238775 18343814 18562315 19004816 19889641 20064389 20356833 21400129 21562258 21849493 21865317 22079575 22315227 22344688 25394490 25637461 27898060 stimulant N/A OmniPath
PLK1 EVI5 16439210 27898060 inhibition N/A OmniPath
PLK1 PRKN 26148234 26387737 27898060 N/A N/A OmniPath
PLK1 TOP2A 18171681 19098900 27898060 stimulant N/A OmniPath
PLK1 BRCA2 12815053 14647413 24448238 27898060 inhibition N/A OmniPath
PLK1 TSC1 16339216 27898060 N/A N/A OmniPath
PLK1 IKBKB 18957422 19202066 27898060 inhibition N/A OmniPath
PLK1 FOXM1 15531365 15654331 15689977 15817462 16314512 16809346 17173139 19160488 19737929 27898060 stimulant N/A OmniPath
FOXM1 PLK1 15531365 15654331 15689977 15817462 16314512 16809346 17173139 19160488 27898060 inhibition,stimulant N/A OmniPath
PLK1 DVL2 20823832 22609948 27898060 stimulant N/A OmniPath
PLK1 RAP1GAP 14660640 25329897 27898060 inhibition N/A OmniPath
PLK1 TANK 20484576 21988832 27898060 N/A N/A OmniPath
PLK1 RAN 16930555 20805321 27898060 stimulant N/A OmniPath
PLK1 CD44 12032545 27898060 N/A N/A OmniPath
PLK1 OPTN 21617041 21862579 22365832 26266977 26365381 26376340 27898060 stimulant N/A OmniPath
PLK1 AQP1 17522053 27898060 N/A N/A OmniPath
PLK1 SRI 24427308 27898060 N/A N/A OmniPath
PLK1 TPT1 12167714 17287340 18669648 20068231 27898060 inhibition,stimulant N/A OmniPath
PLK1 SUGT1 21864708 22869522 27898060 N/A N/A OmniPath
PLK1 CLIP1 20664522 21749319 24451569 27898060 stimulant N/A OmniPath
PLK1 DCTN1 20679239 23661607 27898060 stimulant N/A OmniPath
PLK1 NPR1 27898060 9528788 N/A N/A OmniPath
PLK1 GIT1 16246726 27898060 N/A N/A OmniPath
PLK1 ANAPC1 14657031 27898060 stimulant N/A OmniPath
PLK1 NUDC 12852857 27898060 stimulant N/A OmniPath
PLK1 TRIOBP 22820163 24692559 27898060 stimulant N/A OmniPath
PLK1 RBM8A 16100109 27898060 N/A N/A OmniPath
PLK1 KIZ 16980960 27898060 stimulant N/A OmniPath
PLK1 NINL 12852856 26638075 27898060 stimulant N/A OmniPath
PLK1 ETS2 11027273 12095911 12511603 27898060 N/A N/A OmniPath
PLK1 ORC2 21947279 23188630 27898060 N/A N/A OmniPath
PLK1 CEP55 16198290 16964243 18669648 19413330 19664994 19691289 20068231 27898060 stimulant N/A OmniPath
PLK1 TOPORS 19053840 19473992 19821153 22972498 27898060 inhibition,stimulant N/A OmniPath
PLK1 KIF2B 22535524 27898060 stimulant N/A OmniPath
PLK1 CDC23 14657031 27898060 stimulant N/A OmniPath
PLK1 KCNJ1 12878206 27898060 N/A N/A OmniPath
PLK1 CENPU 17081991 19597481 21454580 27898060 inhibition,stimulant N/A OmniPath
PPP2CB PLK1 27898060 9344838 N/A N/A OmniPath
PLK1 PINX1 20573420 27898060 inhibition,stimulant N/A OmniPath
PLK1 ERCC6L 17218258 19596235 20360068 26496610 27898060 stimulant N/A OmniPath
PLK1 ATXN10 21857149 27898060 inhibition N/A OmniPath
PLK1 CCNT1 23977272 27898060 N/A N/A OmniPath
PLK1 STARD10 15704244 17561512 27898060 N/A N/A OmniPath
PLK1 PLEKHG6 18694934 25336641 27898060 stimulant N/A OmniPath
STK10 PLK1 10980711 11854496 12207013 15611664 15713655 18477460 18615013 20603326 21454580 22081024 22281053 23442801 24349352 24785407 24844881 25660017 26012549 26114094 26206521 27898060 N/A N/A OmniPath
PLK1 COL17A1 17545155 27898060 N/A N/A OmniPath
PLK1 RIOK2 21880710 27898060 N/A N/A OmniPath
PLK1 GCSAM 17489982 27898060 N/A N/A OmniPath
PLK1 NEDD1 18691976 19509060 22595525 27898060 N/A N/A OmniPath
PLK1 CENPQ 25670858 27898060 N/A N/A OmniPath
PLK1 SVIL 23750008 27898060 N/A N/A OmniPath
PLK1 FABP4 1648089 27898060 N/A N/A OmniPath
PLK1 KIF20A 12939256 16565220 18669648 19007248 27898060 N/A N/A OmniPath

Visualization










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