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GENE：MYB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYB
FullNmae MYB proto-oncogene, transcription factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7545
EnsembleID ENSG00000118513
Uniprot P10242

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYB pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYB ferroptosis 37653201 We found that MYB, a highly expressed ferroptosis-related gene, was associated with LDH By leveraging bioinformatics analysis. retulator signature

Go Annotation:

GeneSymbol Go id
MYB GO:0000122,GO:0000278,GO:0000978,GO:0000978,GO:0000981,GO:0001228,GO:0001666,GO:0002931,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006355,GO:0014856,GO:0016363,GO:0030218,GO:0032967,GO:0043525,GO:0045064,GO:0045653,GO:0045892,GO:0045893,GO:0045893,GO:0045944,GO:0045944,GO:0045944,GO:0045944,GO:0048661,GO:0060252,GO:0061515,GO:0070301,GO:0071300,GO:0071636,GO:0090575,GO:1901533,GO:1902895,GO:1904899,GO:2000491,GO:2000845

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYB hsa:4602 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF1 MYB 10739671 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF2 MYB 10739671 23180781 physical association electrophoretic mobility supershift assay InnateDB
PIN1 MYB 18359295 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF6 MYB 18093978 23180781 physical association anti tag coimmunoprecipitation InnateDB
MYB MYB 18093978 23180781 physical association anti tag coimmunoprecipitation InnateDB
LYZ MYB 20524209 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
EGR1 MYB 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL13 MYB 22039304 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL4 MYB 22039304 23180781 physical association anti tag coimmunoprecipitation InnateDB
BCL2 MYB 21795403 23180781 physical association anti tag coimmunoprecipitation InnateDB
BIRC5 MYB 21795403 23180781 physical association anti tag coimmunoprecipitation InnateDB
LEF1 MYB 21795403 23180781 physical association anti tag coimmunoprecipitation InnateDB
MPO MYB 23180781 24121275 physical association anti tag coimmunoprecipitation InnateDB
GFI1 MYB 23180781 24121275 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MYB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
EGR1 MYB 18971253 7559553 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
ESR1 MYB 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator,chromatin immunoprecipitation assay TFlink
ETS1 MYB 18971253 20019798 7848925 8999884 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
GATA1 MYB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MYB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 MYB 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 MYB 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYB MYB 7655015 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
MYBL2 MYB 7655015 trascriptional regulation,stimulation electrophoretic mobility shift assay TFlink
SP1 MYB 7559553 trascriptional regulation,stimulation electrophoretic mobility shift assay TFlink
WT1 MYB 7559553 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
FOXP3 MYB 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MZF1 MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MYB 18971253 8137237 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MYB 18971253 22897851 trascriptional regulation,stimulation inferred by curator TFlink
VDR MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MYB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BCL3 MYB 9694711 trascriptional regulation,stimulation inferred by curator TFlink
FOSL2 MYB 22493372 trascriptional regulation,stimulation inferred by curator TFlink
IRF1 MYB 10739671 trascriptional regulation,stimulation inferred by curator TFlink
JUN MYB 1527086 trascriptional regulation,stimulation inferred by curator TFlink
JUND MYB 1527086 18071306 22493372 trascriptional regulation,stimulation inferred by curator TFlink
TWIST1 MYB 19051271 trascriptional regulation,stimulation inferred by curator TFlink
TWIST2 MYB 19051271 trascriptional regulation,stimulation inferred by curator TFlink
ZFHX3 MYB 15750593 trascriptional regulation,stimulation inferred by curator TFlink
CEBPE MYB N/A trascriptional regulation,stimulation inferred by curator TFlink
ETS2 MYB N/A trascriptional regulation,stimulation inferred by curator TFlink
ETV4 MYB N/A trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 MYB N/A trascriptional regulation,stimulation inferred by curator TFlink
PGR MYB N/A trascriptional regulation,stimulation inferred by curator TFlink
PPARA MYB N/A trascriptional regulation,stimulation inferred by curator TFlink
PPARD MYB N/A trascriptional regulation,stimulation inferred by curator TFlink
PPARG MYB N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A MYB N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000008F0CF MYB 18818396 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS000016FD1A MYB N/A 17923094 18539114 18667440 18814950 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000338542 MYB 20680360 21062812 rna interference,inhibition experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000171CD1 MYB 18818396 21205891 \N rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000EED18 MYB 19584398 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000F0F49 MYB 21062812 rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000171CD1 MYB 18818396 21205891 25416803 28337280 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000EED18 MYB 19584398 21566225 24504520 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002C7B2B MYB 19461653 25416803 mrna cleavage,inhibition array technology TarBase
URS000027352D MYB 19461653 25416803 mrna cleavage,inhibition array technology TarBase
URS000016FD1A MYB 17923094 18539114 18667440 18814950 20603081 21590770 22025269 23521217 23604034 24086639 24438945 24613688 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000008F0CF MYB 18818396 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS0000338542 MYB 20680360 21062812 23807165 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00000F0F49 MYB 21062812 24675898 25416803 mrna cleavage,inhibition western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00000AA464 MYB 20304954 25231743 25416803 mrna cleavage,inhibition array technology,miRNA interference luciferase reporter assay TarBase
URS00000F31F4 MYB 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 MYB 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000BE495 MYB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000008DA94 MYB 22101269 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000012A1DD MYB 22101269 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000171525 MYB 22101269 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS000055BBE5 MYB 22101269 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS000040EE1D MYB 24486218 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000039E1E1 MYB 25416803 26265888 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000F6E49 MYB 25416803 26768615 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 MYB 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPK3 MYB 22135298 phosphorylation N/A PhosphoSite
CEBPE MYB 25361965 interaction type N/A PTMCode2
MYB CEBPE 25361965 interaction type N/A PTMCode2
ZFHX3 MYB 25361965 interaction type N/A PTMCode2
MYB ZFHX3 25361965 interaction type N/A PTMCode2
MYB SND1 25361965 interaction type N/A PTMCode2
SND1 MYB 25361965 interaction type N/A PTMCode2
MYB PAX5 25361965 interaction type N/A PTMCode2
PAX5 MYB 25361965 interaction type N/A PTMCode2
MYB MYBBP1A 25361965 interaction type N/A PTMCode2
MYBBP1A MYB 25361965 interaction type N/A PTMCode2
MYB NLK 25361965 interaction type N/A PTMCode2
NLK MYB 25361965 interaction type N/A PTMCode2
MYB SUMO2 25361965 interaction type N/A PTMCode2
SUMO2 MYB 25361965 interaction type N/A PTMCode2
MAPK1 MYB 25361965 interaction type N/A PTMCode2
MYB MAPK1 25361965 interaction type N/A PTMCode2
MYB CSNK2A1 25361965 interaction type N/A PTMCode2
CLTA MYB 25361965 interaction type N/A PTMCode2
MYB CLTA 25361965 interaction type N/A PTMCode2
CEBPB MYB 25361965 interaction type N/A PTMCode2
MYB CEBPB 25361965 interaction type N/A PTMCode2
NCL MYB 25361965 interaction type N/A PTMCode2
MYB NCL 25361965 interaction type N/A PTMCode2
HIPK2 MYB 25361965 interaction type N/A PTMCode2
MYB HIPK2 25361965 interaction type N/A PTMCode2
MAF MYB 25361965 interaction type N/A PTMCode2
MYB MAF 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I MYB 11779867 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
HSPA8 MYB 25348397 N/A physical interaction ComPPI
TRAF6 MYB 25348397 N/A physical interaction ComPPI
MYOZ2 MYB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NLK MYB 14525934 15082531 15308626 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,IntAct
FBXW7 MYB 14525934 18765672 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SND1 MYB 25348397 N/A physical interaction ComPPI
MAF MYB 14525934 25348397 9566892 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
CREBBP MYB 12196545 14525934 16799563 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
SUMO1 MYB 20802522 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
EP300 MYB 10656693 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PIAS1 MYB 21338522 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CEBPB MYB 11792321 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
KAT2B MYB 25348397 N/A physical interaction ComPPI
FLNA MYB 18548008 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SDC2 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RBX1 MYB 25348397 N/A physical interaction ComPPI
NCOR1 MYB 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
PARP1 MYB 25348397 N/A physical interaction ComPPI
NCAM2 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SIN3A MYB 25348397 N/A physical interaction ComPPI
ASH2L MYB 25348397 N/A physical interaction ComPPI
STAT5A MYB 25348397 N/A physical interaction ComPPI
SPTAN1 MYB 18548008 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RBBP5 MYB 25348397 N/A physical interaction ComPPI
LIN9 MYB 18548008 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
CLTC MYB 18548008 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
TAL1 MYB 24234451 25348397 25394790 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UPF2 MYB 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
SP100 MYB 25348397 N/A physical interaction ComPPI
RPL4 MYB 20604807 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SUMO2 MYB 20802522 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
CUL4A MYB 25348397 N/A physical interaction ComPPI
TRIM28 MYB 25348397 N/A physical interaction ComPPI
CEBPE MYB 10233885 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
HIPK2 MYB 14525934 15082531 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
KAT2A MYB 25348397 N/A physical interaction ComPPI
BEX3 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
DDB1 MYB 25348397 N/A physical interaction ComPPI
ZMYND11 MYB 11244510 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ADAM22 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
FBXL5 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PML MYB 14525934 15194430 20802522 24234451 25348397 27898060 colocalization experimental interaction detection,physical interaction,confocal microscopy ComPPI,HPRD,IntAct,OmniPath
SKI MYB 25348397 N/A physical interaction ComPPI
MAPK11 MYB 14676314 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
ERC2 MYB 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
CCND3 MYB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KMT2A MYB 25348397 N/A physical interaction ComPPI
WDR5 MYB 25348397 N/A physical interaction ComPPI
KAT5 MYB 25348397 N/A physical interaction ComPPI
CLTA MYB 18548008 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FBXW5 MYB 14525934 18765672 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ZFC3H1 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
HLF MYB 25348397 N/A physical interaction ComPPI
PTMS MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
GATA3 MYB 25348397 N/A physical interaction ComPPI
MEN1 MYB 25348397 N/A physical interaction ComPPI
KIF2A MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PCDH17 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
LEF1 MYB 25348397 N/A physical interaction ComPPI
PAX5 MYB 11781241 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CHD3 MYB 25348397 N/A physical interaction ComPPI
NCL MYB 10660576 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SMARCA2 MYB 25348397 N/A physical interaction ComPPI
MYB PPM1K 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MYB COX7B 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MYB KMT2E 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MYB SETD1A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MYB NBPF14 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MAPK1 MYB 14525934 8960373 N/A experimental interaction detection HPRD
TTF2 MYB 12927788 14525934 N/A two hybrid HPRD
MYBBP1A MYB 14525934 27898060 8302594 9447996 N/A experimental interaction detection HPRD,OmniPath
CSNK2A1 MYB 11313925 14525934 N/A experimental interaction detection HPRD
ZFHX3 MYB 10318867 14525934 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
MYB CNOT9 14525934 15209511 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
MYB FBXW2 14525934 18765672 N/A experimental interaction detection HPRD
MYB SKP2 14525934 18765672 N/A experimental interaction detection HPRD
MYB BTRC 14525934 18765672 N/A experimental interaction detection HPRD
MYB TRAF7 16162816 27898060 N/A N/A OmniPath
MYB COL1A2 27898060 9989795 stimulant N/A OmniPath
MYB PIN1 18359295 27898060 N/A N/A OmniPath
TRAF6 MYB 18093978 27898060 inhibition N/A OmniPath
NCL MYB 10660576 27898060 inhibition N/A OmniPath
MYB GATA3 17641686 27898060 stimulant N/A OmniPath
MAF MYB 27898060 9566892 inhibition N/A OmniPath
MAPK3 MYB 11313925 27898060 7735324 8798443 8960373 inhibition N/A OmniPath
CREBBP MYB 11073948 12196545 14761981 16055500 16799563 18585056 23980173 27898060 stimulant N/A OmniPath
MYB COL1A1 27898060 9989795 stimulant N/A OmniPath
EP300 MYB 10656693 11585920 15691758 18585056 19608861 20364308 27898060 stimulant N/A OmniPath
MAPK1 MYB 19651622 27898060 8960373 N/A N/A OmniPath
CSNK2A1 MYB 11313925 27898060 7735324 N/A N/A OmniPath
NLK MYB 12482967 15082531 15308626 16055500 27898060 inhibition,stimulant N/A OmniPath
CAMK2A MYB 27898060 8960373 N/A N/A OmniPath

Visualization










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