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GENE：CAPZB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CAPZB
FullNmae capping actin protein of muscle Z-line subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1491
EnsembleID ENSG00000077549
Uniprot P47756

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CAPZB ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CAPZB disulfidptosis 39701955 This study put forward a predictive model containing disulfidptosis-associated genes (DRGs) of GYS1, MYH10, PDMIL1, SLC3A2, CAPZB, showing excellent performance by SVM machine learning model. retulator signature

Go Annotation:

GeneSymbol Go id
CAPZB GO:0000902,GO:0003779,GO:0005515,GO:0005829,GO:0005856,GO:0005903,GO:0007010,GO:0008154,GO:0008290,GO:0010591,GO:0014069,GO:0015629,GO:0016020,GO:0022604,GO:0030017,GO:0030027,GO:0030032,GO:0030863,GO:0045296,GO:0051015,GO:0051016,GO:0051490,GO:0070062,GO:0071203,GO:0097224,GO:0098685,GO:0098686

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CAPZB hsa:832 path:hsa04144 Endocytosis - Homo sapiens (human)
CAPZB hsa:832 path:hsa04814 Motor proteins - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R CAPZB 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
CAPZB TLR9 17353931 23180781 physical association unspecified method InnateDB
BMI1 CAPZB 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR CAPZB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CAPZB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CAPZB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CAPZB 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CAPZB 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C CAPZB 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CAPZB 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 CAPZB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB CAPZB 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000EED18 CAPZB 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00005651EE CAPZB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D CAPZB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003ACE11 CAPZB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005FDE70 CAPZB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005485E8 CAPZB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC CAPZB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B CAPZB 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 CAPZB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 CAPZB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 CAPZB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE CAPZB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A CAPZB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D CAPZB 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004DEA91 CAPZB 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 CAPZB 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 CAPZB 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA CAPZB 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 CAPZB 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 CAPZB 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000424278 CAPZB 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 CAPZB 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 CAPZB 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000B989F CAPZB 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F CAPZB 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 CAPZB 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000319E1 CAPZB 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001A7F58 CAPZB 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000486E0B CAPZB 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CCD18 CAPZB 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B0E50 CAPZB 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AD2AA CAPZB 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ARPC3 CAPZB 25348397 N/A physical interaction ComPPI
CDC73 CAPZB 25348397 N/A physical interaction ComPPI
HSPA8 CAPZB 25348397 N/A physical interaction ComPPI
SH3KBP1 CAPZB 25348397 N/A physical interaction ComPPI
PPP1CC CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
BAG3 CAPZB 25348397 N/A physical interaction ComPPI
TP53BP1 CAPZB 25348397 N/A physical interaction ComPPI
TRAF6 CAPZB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GABARAPL2 CAPZB 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PPP1CB CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
BMI1 CAPZB 25348397 N/A physical interaction ComPPI
KEAP1 CAPZB 25348397 N/A physical interaction ComPPI
MCM2 CAPZB 25348397 N/A physical interaction ComPPI
MAP1LC3B CAPZB 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
STAP1 CAPZB 25348397 N/A physical interaction ComPPI
UBL7 CAPZB 25348397 N/A physical interaction ComPPI
EGLN3 CAPZB 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
BLNK CAPZB 25348397 N/A physical interaction ComPPI
CD2AP CAPZB 25348397 N/A physical interaction ComPPI
SP1 CAPZB 25348397 N/A physical interaction ComPPI
GRB2 CAPZB 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN CAPZB 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
TPM2 CAPZB 25348397 N/A physical interaction ComPPI
GLI1 CAPZB 25348397 N/A physical interaction ComPPI
FLNA CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
U2AF2 CAPZB 25348397 N/A physical interaction ComPPI
PAXIP1 CAPZB 25348397 N/A physical interaction ComPPI
DLD CAPZB 25348397 N/A physical interaction ComPPI
NTRK1 CAPZB 25348397 N/A physical interaction ComPPI
CDH1 CAPZB 25348397 N/A physical interaction ComPPI
CAPZA1 CAPZB 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
DCTN1 CAPZB 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
IQGAP1 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
VCL CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CFTR CAPZB 25348397 N/A physical interaction ComPPI
PDLIM7 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
MYO18A CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
BCCIP CAPZB 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HUWE1 CAPZB 25348397 N/A physical interaction ComPPI
CDK2 CAPZB 25348397 N/A physical interaction ComPPI
NAPA CAPZB 25348397 N/A physical interaction ComPPI
VHL CAPZB 25348397 N/A physical interaction ComPPI
MARK2 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
OCRL CAPZB 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MDC1 CAPZB 25348397 N/A physical interaction ComPPI
RIPK3 CAPZB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
VCAM1 CAPZB 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 CAPZB 25348397 N/A physical interaction ComPPI
HEXA CAPZB 25348397 N/A physical interaction ComPPI
CUL7 CAPZB 25348397 N/A physical interaction ComPPI
MARK3 CAPZB 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 CAPZB 25348397 N/A physical interaction ComPPI
GAK CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
ESR1 CAPZB 21182205 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
BRCA1 CAPZB 25348397 N/A physical interaction ComPPI
MCFD2 CAPZB 25348397 N/A physical interaction ComPPI
MAP3K3 CAPZB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HECW2 CAPZB 25348397 N/A physical interaction ComPPI
MYO5B CAPZB 25348397 N/A physical interaction ComPPI
MAGOH CAPZB 25348397 N/A physical interaction ComPPI
SYNPO CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UIMC1 CAPZB 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCTN2 CAPZB 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
ANLN CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
IKBKE CAPZB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ARPC5 CAPZB 25348397 N/A physical interaction ComPPI
ARHGAP17 CAPZB 25348397 N/A physical interaction ComPPI
PAN2 CAPZB 25348397 N/A physical interaction ComPPI
CNOT1 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CNOT2 CAPZB 25348397 N/A physical interaction ComPPI
DCTN4 CAPZB 25348397 N/A physical interaction ComPPI
ACTR1B CAPZB 25348397 N/A physical interaction ComPPI
TES CAPZB 25348397 N/A physical interaction ComPPI
PLEKHO1 CAPZB 25348397 N/A physical interaction ComPPI
EIF4A3 CAPZB 25348397 N/A physical interaction ComPPI
STYX CAPZB 25348397 N/A physical interaction ComPPI
RPP14 CAPZB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WASHC2C CAPZB 25348397 N/A physical interaction ComPPI
TOMM40 CAPZB 25348397 N/A physical interaction ComPPI
MYH9 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
ARPC2 CAPZB 25348397 N/A physical interaction ComPPI
MCC CAPZB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PTN CAPZB 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAPSS1 CAPZB 25348397 N/A physical interaction ComPPI
TUBB3 CAPZB 25348397 N/A physical interaction ComPPI
SIRT6 CAPZB 25348397 N/A physical interaction ComPPI
PCID2 CAPZB 25348397 N/A physical interaction ComPPI
GABARAPL1 CAPZB 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MRPL20 CAPZB 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DCTPP1 CAPZB 25348397 N/A physical interaction ComPPI
ARPC5L CAPZB 25348397 N/A physical interaction ComPPI
LIMA1 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
RPAP3 CAPZB 25348397 N/A physical interaction ComPPI
DBN1 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
TWF2 CAPZB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DMWD CAPZB 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO6 CAPZB 25348397 N/A physical interaction ComPPI
GH1 CAPZB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MC1R CAPZB 25348397 N/A physical interaction ComPPI
MYH11 CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
FN1 CAPZB 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
TP53 CAPZB 25348397 N/A physical interaction ComPPI
BCAR1 CAPZB 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
AHCY CAPZB 25348397 N/A physical interaction ComPPI
CAPZB MEPCE 25348397 N/A physical interaction ComPPI
CAPZB PPP2R2B 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CAPZB UBE2Q2 25348397 N/A physical interaction ComPPI
CAPZB LRRK2 25348397 N/A physical interaction ComPPI
CAPZB CAPZA2 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CAPZB OBSL1 25348397 N/A physical interaction ComPPI
CAPZB CCDC8 25348397 N/A physical interaction ComPPI
CAPZB DAPK1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CAPZB PLEKHO2 25348397 N/A physical interaction ComPPI
CAPZB CARMIL1 25348397 N/A physical interaction ComPPI
CAPZB DCTN6 25348397 N/A physical interaction ComPPI
CAPZB DDX53 25348397 N/A physical interaction ComPPI
CAPZB TMOD3 25348397 N/A physical interaction ComPPI
CAPZB RPGRIP1L 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CAPZB VPS26A 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CAPZB MYO5C 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CAPZB MYO19 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CAPZB DUSP8 25348397 N/A physical interaction ComPPI
CAPZB RCSD1 25348397 N/A physical interaction ComPPI
CAPZB COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CAPZB RNF169 25348397 N/A physical interaction ComPPI
MTPN CAPZB 12488317 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
NDUFA7 CAPZB 24234451 30021884 physical association cross-linking study IntAct
CAPZB CCDC33 24234451 30021884 physical association cross-linking study IntAct
H2BC9 CAPZB 24234451 30021884 physical association cross-linking study IntAct
L1TD1 CAPZB 24234451 25702638 association anti bait coimmunoprecipitation IntAct
IL7R CAPZB 20167604 27898060 N/A N/A OmniPath
TLR9 CAPZB 17353931 27898060 N/A N/A OmniPath
ROCK2 CAPZB 14517206 27898060 stimulant N/A OmniPath

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