Gene Information gene info

  1. Home

GENE：EPHB4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EPHB4
FullNmae EPH receptor B4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3395
EnsembleID ENSG00000196411
Uniprot P54760

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EPHB4 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EPHB4 GO:0001525,GO:0001525,GO:0002042,GO:0003007,GO:0004714,GO:0004714,GO:0005003,GO:0005515,GO:0005524,GO:0005576,GO:0005829,GO:0005886,GO:0005886,GO:0007155,GO:0007275,GO:0033674,GO:0043235,GO:0046777,GO:0048013,GO:0048013,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EPHB4 hsa:2050 path:hsa04360 Axon guidance - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EPHB4 KPNA2 23180781 25724901 physical association anti tag coimmunoprecipitation InnateDB
EPHB4 QRFPR 23180781 25724901 physical association anti tag coimmunoprecipitation InnateDB
EPHB4 LEF1 23180781 25724901 physical association anti tag coimmunoprecipitation InnateDB
EPHB4 CCDC68 23180781 25724901 physical association anti tag coimmunoprecipitation InnateDB
EPHB4 GALNT16 23180781 25724901 physical association anti tag coimmunoprecipitation InnateDB
EPHB4 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB
EFNB2 EPHB4 12051776 18988627 23331499 9576626 9718367 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
GATA1 EPHB4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 EPHB4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HOXA9 EPHB4 14764452 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C EPHB4 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 EPHB4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002B3783 EPHB4 22438230 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002B3783 EPHB4 22438230 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000237AF9 EPHB4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000DDD35 EPHB4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000239117 EPHB4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004F859B EPHB4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000006DA05 EPHB4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000018E72A EPHB4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF EPHB4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D EPHB4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000D6C3F EPHB4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000031BC7D EPHB4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC EPHB4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 EPHB4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 EPHB4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 EPHB4 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
JUN EPHB4 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
EPHB6 EPHB4 25348397 N/A physical interaction ComPPI
GRIN1 EPHB4 11136979 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PARD6A EPHB4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PKM EPHB4 25348397 N/A protein kinase assay ComPPI
EFNB2 EPHB4 12051776 14525934 24234451 25348397 26481148 9718367 N/A experimental interaction detection,surface plasmon resonance,physical interaction,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
EGFR EPHB4 15657067 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SDC3 EPHB4 14525934 25348397 9388509 N/A experimental interaction detection,in vitro ComPPI,HPRD
EPHB4 ELAVL1 25348397 N/A physical interaction ComPPI
EPHB4 APP 25348397 N/A physical interaction ComPPI
EPHB4 HLA-DRA 25348397 N/A physical interaction ComPPI
EPHB4 GABRE 25348397 N/A physical interaction ComPPI
EPHB4 HLA-E 25348397 N/A physical interaction ComPPI
EPHB4 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EPHB4 ZSCAN5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EPHB4 SCGB2A2 25348397 N/A physical interaction ComPPI
EPHB4 TCTN2 25348397 N/A physical interaction ComPPI
EPHB4 MANSC1 25348397 N/A physical interaction ComPPI
EPHB4 KLRG2 25348397 N/A physical interaction ComPPI
EPHB4 PCDHGA5 25348397 N/A physical interaction ComPPI
EPHB4 TMPRSS3 25348397 N/A physical interaction ComPPI
EPHB4 LRRIQ1 25348397 N/A physical interaction ComPPI
EPHB4 MRAP2 25348397 N/A physical interaction ComPPI
EPHB4 ADPGK 25348397 N/A physical interaction ComPPI
EPHB4 ST8SIA4 25348397 N/A physical interaction ComPPI
EPHB4 P2RX2 25348397 N/A physical interaction ComPPI
EPHB4 NRROS 25348397 N/A physical interaction ComPPI
EPHB4 MME 25348397 N/A physical interaction ComPPI
EPHB4 PCDHAC2 25348397 N/A physical interaction ComPPI
EPHB4 IL17RC 25348397 N/A physical interaction ComPPI
EPHB4 PCDHA12 25348397 N/A physical interaction ComPPI
EPHB4 EPO 24234451 25348397 26481148 physical association anti bait coimmunoprecipitation,solid phase assay ComPPI,IntAct
TANK EPHB4 24234451 30561431 association virotrap IntAct
H1-2 EPHB4 24234451 30021884 physical association cross-linking study IntAct
KPNA2 EPHB4 25724901 27898060 N/A N/A OmniPath
EFNB2 EPHB4 12051776 27898060 7534404 9718367 N/A N/A OmniPath
EFNB1 EPHB4 27898060 9330863 stimulant N/A OmniPath
EFNB3 EPHB4 27898060 8755474 N/A N/A OmniPath

Visualization










  Return