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GENE：RAB27A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAB27A
FullNmae RAB27A, member RAS oncogene family
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9766
EnsembleID ENSG00000069974
Uniprot P51159

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAB27A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RAB27A ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RAB27A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RAB27A GO:0001750,GO:0003924,GO:0003925,GO:0005515,GO:0005525,GO:0005525,GO:0005525,GO:0005576,GO:0005764,GO:0005770,GO:0005794,GO:0005829,GO:0006887,GO:0006887,GO:0007596,GO:0010628,GO:0016324,GO:0019003,GO:0019882,GO:0019904,GO:0030141,GO:0030318,GO:0030425,GO:0031489,GO:0032400,GO:0032402,GO:0032585,GO:0033093,GO:0033162,GO:0035580,GO:0036257,GO:0042470,GO:0042470,GO:0043316,GO:0043320,GO:0045921,GO:0045921,GO:0048489,GO:0050766,GO:0070062,GO:0070382,GO:0070382,GO:0071985,GO:0097278,GO:1903307,GO:1903307,GO:1903428,GO:1903435,GO:1990182

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SNAP23 RAB27A 20634814 26192618 interaction type N/A ACSN
STXBP2 RAB27A 20634814 26192618 interaction type N/A ACSN
UNC13D RAB27A 20634814 26192618 interaction type N/A ACSN
RAB27A SYTL1 15998322 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
RAB27A CFTR 16762324 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR RAB27A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RAB27A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 RAB27A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RAB27A 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RAB27A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR RAB27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 RAB27A 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 RAB27A 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 RAB27A 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000001EB3 RAB27A 22948084 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00000B0E50 RAB27A 23295946 25416803 26384136 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000475586 RAB27A 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001FC26E RAB27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 RAB27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F RAB27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD RAB27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000038446A RAB27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC RAB27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 RAB27A 25416803 28043921 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000AA464 RAB27A 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000042935A RAB27A 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000C5BAA RAB27A 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GZMB RAB27A 25361965 interaction type N/A PTMCode2
RAB27A GZMB 25361965 interaction type N/A PTMCode2
MLPH RAB27A 25361965 interaction type N/A PTMCode2
RAB27A MLPH 25361965 interaction type N/A PTMCode2
STX1A RAB27A 25361965 interaction type N/A PTMCode2
RAB27A STX1A 25361965 interaction type N/A PTMCode2
RAB27A RPH3A 25361965 interaction type N/A PTMCode2
RPH3A RAB27A 25361965 interaction type N/A PTMCode2
MYRIP RAB27A 25361965 interaction type N/A PTMCode2
RAB27A MYRIP 25361965 interaction type N/A PTMCode2
RPH3AL RAB27A 25361965 interaction type N/A PTMCode2
RAB27A RPH3AL 25361965 interaction type N/A PTMCode2
SYTL4 RAB27A 25361965 interaction type N/A PTMCode2
RAB27A SYTL4 25361965 interaction type N/A PTMCode2
RABGGTB RAB27A 25361965 interaction type N/A PTMCode2
RAB27A RABGGTB 25361965 interaction type N/A PTMCode2
UNC13D RAB27A 25361965 interaction type N/A PTMCode2
RAB27A UNC13D 25361965 interaction type N/A PTMCode2
SYTL5 RAB27A 25361965 interaction type N/A PTMCode2
RAB27A SYTL5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RABGGTB RAB27A 12802062 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RPH3AL RAB27A 12578829 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYTL4 RAB27A 11773082 11865063 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
RIMS2 RAB27A 12578829 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RPH3A RAB27A 12578829 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EEF1A1 RAB27A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SYTL5 RAB27A 12051743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RIMS1 RAB27A 12578829 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GDI1 RAB27A 12802062 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ZBTB16 RAB27A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
STX1A RAB27A 12101244 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ADRB2 RAB27A 25348397 N/A physical interaction ComPPI
RAB27A MLPH 11773082 11856727 11887186 11980908 12062444 12578829 12897212 14525934 15059972 17045265 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
RAB27A SYTL2 25348397 N/A physical interaction,in vitro,in vivo ComPPI
RAB27A SYTL1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,IntAct
RAB27A MYRIP 12590134 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
RAB27A SYTL3 11773082 12590134 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
RAB27A UNC13D 14525934 14699162 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RAB27A GDF9 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAB27A ERG28 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAB27A RBM48 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAB27A COPS6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAB27A CEP126 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RAB27A LRIF1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RAB27A EEF1A1P5 25348397 N/A physical interaction ComPPI
RAB27A MYO5A 12006666 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RAB27A EXPH5 12189142 12590134 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RAB27A APP 25348397 N/A physical interaction ComPPI
RAB27A FBXO6 25348397 N/A physical interaction ComPPI
RAB27A UNC13B 25348397 N/A physical interaction ComPPI
RAB27A RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RAB27A GZMB 11266473 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
CFTR RAB27A 16762324 27898060 N/A N/A OmniPath

Visualization










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