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GENE：AIMP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AIMP2
FullNmae aminoacyl tRNA synthetase complex interacting multifunctional protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20609
EnsembleID ENSG00000106305
Uniprot Q13155

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AIMP2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AIMP2 GO:0005515,GO:0005634,GO:0005829,GO:0005829,GO:0006412,GO:0006915,GO:0008285,GO:0016020,GO:0016567,GO:0017101,GO:0017101,GO:0031398,GO:0060090,GO:0060510,GO:0065003

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AIMP2 BRME1 16189514 23180781 physical association pull down InnateDB
BYSL AIMP2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 AIMP2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 AIMP2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C AIMP2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA AIMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AIMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC AIMP2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 AIMP2 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 AIMP2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000EC1BE AIMP2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000031B6ED AIMP2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MAPK14 AIMP2 22135298 phosphorylation N/A PhosphoSite
AIMP2 AIMP1 25361965 interaction type N/A PTMCode2
AIMP1 AIMP2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BYSL AIMP2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BCAS2 AIMP2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLU7 AIMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V1D AIMP2 25348397 N/A physical interaction ComPPI
C1ORF216 AIMP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FHL3 AIMP2 14525934 16189514 21516116 24234451 25348397 25416956 27107012 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid,two hybrid ComPPI,HPRD,IntAct
AIMP2 NECAB2 25348397 N/A two hybrid,physical interaction ComPPI
AIMP2 PRKAA2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 PLEKHF2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 MIS18A 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 KARS1 12819782 16189514 19584093 21536907 21900206 21988832 22751010 22939629 24212136 24234451 25348397 25416956 26344197 27898060 29997244 9878398 physical association bioluminescence resonance energy transfer,two hybrid,molecular sieving,pull down,x-ray crystallography,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,luminescence based mammalian interactome mapping,x ray scattering,amplified luminescent proximity homogeneous assay,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
AIMP2 PRKN 12783850 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
AIMP2 FUBP1 21285945 21988832 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,fluorescence microscopy,in vitro,in vivo ComPPI,IntAct
AIMP2 EPS8 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AIMP2 BRME1 14525934 16189514 19060904 21516116 24234451 25348397 25416956 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
AIMP2 LNX1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
AIMP2 DARS1 14525934 16189514 21900206 24234451 25348397 25416956 9878398 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
AIMP2 EPRS1 14525934 18695251 24234451 25348397 9878398 physical association experimental interaction detection,molecular sieving,physical interaction,in vivo ComPPI,HPRD,IntAct
AIMP2 LMO3 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AIMP2 AIMP2 14525934 25348397 600859 N/A experimental interaction detection,physical interaction ComPPI,HPRD
AIMP2 RARS1 25348397 N/A physical interaction ComPPI
AIMP2 IARS1 25348397 N/A physical interaction ComPPI
AIMP2 DARS2 25348397 N/A physical interaction ComPPI
AIMP2 QARS1 21285945 24234451 25348397 colocalization cosedimentation,physical interaction,fluorescence microscopy ComPPI,IntAct
AIMP2 TP53 18695251 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct,OmniPath
AIMP2 STUB1 25348397 N/A physical interaction ComPPI
AIMP2 HSPA4 25348397 N/A physical interaction ComPPI
AIMP2 DEAF1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 KDR 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 KLC2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 CEP126 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 MATR3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 BLOC1S4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 ZC3H12A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 DSN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 PPP2R1A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 CHD3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 MCF2L 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 TRMT2A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 ACTB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 ICE1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 FGB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 LUC7L2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 TERF2IP 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
AIMP2 TRAF2 25348397 N/A physical interaction ComPPI
AIMP2 BIRC2 25348397 N/A physical interaction ComPPI
AIMP2 APP 25348397 N/A physical interaction ComPPI
AIMP2 AIMP1 12729910 12819782 14525934 22863883 22939629 24234451 25348397 25416956 26344197 27898060 9878398 physical association experimental interaction detection,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,inference by socio-affinity scoring ComPPI,HPRD,IntAct,OmniPath
AIMP2 LARS1 25348397 N/A physical interaction ComPPI
AIMP2 MARS1 25348397 N/A physical interaction ComPPI
AIMP2 EEF1E1 25348397 N/A physical interaction ComPPI
AIMP2 UBA1 25348397 N/A physical interaction ComPPI
AIMP2 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
AIMP2 BAG3 25348397 N/A physical interaction ComPPI
AIMP2 BEX3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 TANK 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AIMP2 EIF4G1 25348397 N/A physical interaction ComPPI
AIMP2 CCAR2 25348397 N/A physical interaction ComPPI
AIMP2 RPL27A 25348397 N/A physical interaction ComPPI
AIMP2 HNRNPA1 25348397 N/A physical interaction ComPPI
AIMP2 IQGAP1 25348397 N/A physical interaction ComPPI
AIMP2 PSMC6 25348397 N/A physical interaction ComPPI
AIMP2 PTBP1 25348397 N/A physical interaction ComPPI
AIMP2 GYS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 LMO2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 PCMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 TFIP11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 NDEL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 ZGPAT 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 SDCBP 25348397 N/A physical interaction ComPPI
AIMP2 CIAPIN1 25348397 N/A physical interaction ComPPI
AIMP2 PUF60 25348397 N/A physical interaction ComPPI
AIMP2 ATP6V1E1 25348397 N/A physical interaction ComPPI
AIMP2 PIN4 25348397 N/A physical interaction ComPPI
AIMP2 PSMD4 25348397 N/A physical interaction ComPPI
AIMP2 TWF1 25348397 N/A physical interaction ComPPI
AIMP2 NTRK1 25348397 N/A physical interaction ComPPI
AIMP2 NETO2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AIMP2 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AIMP2 C1ORF131 25348397 N/A physical interaction ComPPI
AIMP2 SMURF2 25348397 N/A physical interaction ComPPI
AIMP2 TRAF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AIMP2 OFD1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AIMP2 DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
AIMP2 BRCA1 25348397 N/A physical interaction ComPPI
AIMP2 VPS35 25348397 N/A physical interaction ComPPI
AIMP2 PARP1 25348397 N/A physical interaction ComPPI
AIMP2 HNRNPL 25348397 N/A physical interaction ComPPI
AIMP2 KEAP1 25348397 N/A physical interaction ComPPI
AIMP2 UBB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
AIMP2 UBC 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
AIMP2 RPS27A 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
AIMP2 UBA52 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
AIMP2 CEP170P1 16189514 24234451 25348397 25416956 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIMP2 EIF1B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
AIMP2 PML 21285945 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
AIMP2 LMNA 21285945 24234451 25348397 colocalization cosedimentation,cosedimentation in solution ComPPI,IntAct
AIMP2 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
AIMP2 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
AIMP2 MAPK6 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
AIMP2 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
AIMP2 SPATA18 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 TEX12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 ANKRD36BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 KRT33B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 RABEP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 KRT31 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 SBK3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 DDIT4L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 PFDN6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
AIMP2 PSMA1 24234451 25348397 29568061 association pull down ComPPI,IntAct
AIMP2 ECH1 24234451 25348397 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
NCBP3 AIMP2 24234451 26382858 association pull down IntAct
PRKN AIMP2 12783850 16049031 16135753 16714300 27898060 inhibition,stimulant N/A OmniPath

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