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GENE：ANXA3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ANXA3
FullNmae annexin A3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:541
EnsembleID ENSG00000138772
Uniprot P12429

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ANXA3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ANXA3 ferroptosis 38393971 Mechanistically, ANXA3 in exosomes inhibited the ubiquitination of ATF2, whereas ATF2 acted as a transcription factor to regulate the expression of CHAC1, thus inhibiting ferroptosis in LSCC cells. retulator signature

Go Annotation:

GeneSymbol Go id
ANXA3 GO:0005509,GO:0005544,GO:0005737,GO:0005737,GO:0005886,GO:0006909,GO:0010595,GO:0016020,GO:0019834,GO:0021766,GO:0030424,GO:0030425,GO:0030670,GO:0031100,GO:0042581,GO:0042742,GO:0043025,GO:0043312,GO:0045766,GO:0048306,GO:0051054,GO:0051091,GO:0051384,GO:0070062,GO:0070848

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ISG15 ANXA3 16009940 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ANXA3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 ANXA3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 ANXA3 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ANXA3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 ANXA3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 ANXA3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ANXA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ANXA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ANXA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ANXA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ANXA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ANXA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ANXA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ANXA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 ANXA3 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
SSNA1 ANXA3 25348397 N/A physical interaction ComPPI
ISG15 ANXA3 25348397 N/A physical interaction ComPPI
REG3A ANXA3 10662590 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
ANXA4 ANXA3 25348397 N/A physical interaction ComPPI
UNC119 ANXA3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CFTR ANXA3 25348397 N/A physical interaction ComPPI
SNAP23 ANXA3 25348397 N/A physical interaction ComPPI
STX4 ANXA3 25348397 N/A physical interaction ComPPI
STXBP2 ANXA3 25348397 N/A physical interaction ComPPI
ANXA11 ANXA3 25348397 N/A physical interaction ComPPI
PTPA ANXA3 25348397 N/A physical interaction ComPPI
ATF2 ANXA3 22304920 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TES ANXA3 25348397 N/A physical interaction ComPPI
ANXA3 UBR1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ANXA3 IGSF21 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ANXA3 EMG1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ANXA3 TP53 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ISG15 ANXA3 16009940 27898060 N/A N/A OmniPath

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