GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
INF2 |
| FullNmae |
inverted formin 2 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:23791 |
| EnsembleID |
ENSG00000203485 |
| Uniprot |
Q27J81 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| INF2 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
| INF2 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
| INF2 |
disulfidptosis |
39146597 |
Previous studies have identified 15 essential genes (FLNA, FLNB, MYH9, TLN1, ACTB, MYL6, MYH10, CAPZB, DSTN, IQGAP1, ACTN4, PDLIM1, CD2AP, INF2, SLC7A11) associated with disulfidptosis. |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| INF2 |
GO:0003779,GO:0005515,GO:0005884,GO:0030041,GO:0031267,GO:0048471,GO:0090140 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| E2F4 |
INF2 |
17531812
18971253
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array,inferred by curator |
TFlink |
| ETS1 |
INF2 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA1 |
INF2 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
INF2 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| TFAP2C |
INF2 |
20629094
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| TRIM28 |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| ZNF263 |
INF2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00001A6D0C |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00003804D8 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000149319 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000054DF42 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000C48FA |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00004AD450 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000247AC6 |
INF2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| CHEK1 |
INF2 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| PPP1CC |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| TOMM22 |
INF2 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
| VCP |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PPP1CB |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| CRK |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBE2R2 |
INF2 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| FLNA |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CANX |
INF2 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
| PFN2 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PPP1CA |
INF2 |
24234451
25348397
25593058
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
| CSNK2A1 |
INF2 |
25348397
|
N/A |
physical interaction,protein kinase assay |
ComPPI |
| HNRNPL |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| IQGAP1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MYO18A |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TRIM25 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GAK |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| TOMM20 |
INF2 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
| SYNPO |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ANLN |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| ACTR2 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| IFI16 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MYH9 |
INF2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| MYO1C |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CD55 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ADD1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| LIMA1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| DBN1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MYH11 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| NXF1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GCN1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CAPZA2 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MOV10 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TMOD3 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RSPRY1 |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MYO5C |
INF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| INF2 |
MYO19 |
25348397
|
N/A |
physical interaction |
ComPPI |
| INF2 |
CFAP97 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| BDKRB2 |
INF2 |
24234451
28298427
|
physical association |
ubiquitin reconstruction |
IntAct |
Visualization