Gene Information gene info

GENE:KIF22

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KIF22
FullNmae kinesin family member 22
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6391
EnsembleID ENSG00000079616
Uniprot Q14807

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KIF22 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KIF22 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KIF22 GO:0000278,GO:0000776,GO:0000785,GO:0003677,GO:0003777,GO:0005515,GO:0005524,GO:0005634,GO:0005829,GO:0005829,GO:0005871,GO:0005874,GO:0006281,GO:0007018,GO:0007062,GO:0007080,GO:0008017,GO:0016607,GO:0016887,GO:0051310,GO:0072686

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KIF22 hsa:3835 path:hsa04814 Motor proteins - Homo sapiens (human)
KIF22 hsa:3835 path:hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 KIF22 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 KIF22 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 KIF22 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 KIF22 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KIF22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KIF22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KIF22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 KIF22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 KIF22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KIF22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KIF22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR KIF22 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFBE3 KIF22 19944095 rna interference,inhibition western blot miRSponge
URS00001EFBE3 KIF22 19944095 25416803 mrna cleavage,inhibition western blot TarBase
URS00000AA464 KIF22 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 KIF22 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000C85B2 KIF22 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D KIF22 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC864 KIF22 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 KIF22 22135298 phosphorylation N/A PhosphoSite
CDK2 KIF22 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
BCL2L11 KIF22 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
KPNA3 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KPNA4 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CD2BP2 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAF12 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATXN1 KIF22 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
H2BC4 KIF22 25348397 N/A physical interaction ComPPI
COX5A KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRK KIF22 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
RPL10 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MPDZ KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPK14 KIF22 25348397 N/A physical interaction ComPPI
SIAH1 KIF22 11146551 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
C4A KIF22 25348397 N/A physical interaction ComPPI
PSEN2 KIF22 25348397 N/A physical interaction ComPPI
STAT6 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNB1 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC14B KIF22 25348397 N/A physical interaction ComPPI
LIMS1 KIF22 25348397 N/A physical interaction ComPPI
PJA1 KIF22 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
H3C1 KIF22 25348397 N/A physical interaction ComPPI
SVIL KIF22 14525934 20309963 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FOXE1 KIF22 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
IMMT KIF22 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GDF9 KIF22 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCNL2 KIF22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHF21A KIF22 25348397 N/A physical interaction ComPPI
BRCA1 KIF22 25348397 N/A physical interaction ComPPI
TEAD2 KIF22 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
KIF22 CHFR 25348397 N/A physical interaction ComPPI
KIF22 MOV10 25348397 N/A physical interaction ComPPI
KIF22 NXF1 25348397 N/A physical interaction ComPPI
KIF22 OBSL1 25348397 N/A physical interaction ComPPI
KIF22 H2BC11 25348397 N/A physical interaction ComPPI
KIF22 FUS 25348397 N/A physical interaction ComPPI
KIF22 SP110 25348397 N/A physical interaction ComPPI
KIF22 RBM45 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 CEP350 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 HMGXB4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 MARCHF6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 CEPT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 CKAP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 SFMBT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 EPB41L4B 25348397 N/A physical interaction ComPPI
KIF22 BIRC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 ZNF668 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 WDCP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 C18ORF21 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 UTP23 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 PSRC1 25348397 N/A physical interaction ComPPI
KIF22 UTP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 KNSTRN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 PGM2L1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF22 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
KIF22 FOXM1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
KIF22 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
KIF22 TBC1D15 25348397 N/A physical interaction ComPPI
KIF22 CNPY2 25348397 N/A physical interaction ComPPI
KIF22 USP47 25348397 N/A physical interaction ComPPI
KIF22 ZYG11B 25348397 N/A physical interaction ComPPI
KIF22 C4B 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
H3-4 KIF22 24234451 30021884 physical association cross-linking study IntAct
H1-5 KIF22 24234451 30021884 physical association cross-linking study IntAct
NPM1 KIF22 24234451 30021884 physical association cross-linking study IntAct
H2BS1 KIF22 24234451 30021884 physical association cross-linking study IntAct
H1-4 KIF22 24234451 30021884 physical association cross-linking study IntAct
CDK1 KIF22 12727876 27898060 stimulant N/A OmniPath
TBK1 KIF22 12727876 27898060 N/A N/A OmniPath

Visualization