Gene Information gene info

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GENE：LGALS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LGALS1
FullNmae galectin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6561
EnsembleID ENSG00000100097
Uniprot P09382

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LGALS1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LGALS1 GO:0002317,GO:0003723,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005737,GO:0005788,GO:0005829,GO:0006915,GO:0030246,GO:0031295,GO:0042981,GO:0043065,GO:0043123,GO:0043236,GO:0045445,GO:0046598,GO:0050729,GO:0062023,GO:0062023,GO:0070062,GO:0098609,GO:1990724

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LGALS1 FAP 21191065 21385934 26192618 interaction type N/A ACSN
LGALS1 CCL2 21191065 21385934 26192618 interaction type N/A ACSN
LGALS1 GEMIN4 11522829 23180781 physical association two hybrid InnateDB
LGALS1 GEMIN2 11522829 23180781 physical association anti tag coimmunoprecipitation InnateDB
LGALS1 LGALS3 11522829 23180781 physical association anti tag coimmunoprecipitation InnateDB
LGALS1 SMN1 11522829 23180781 physical association anti tag coimmunoprecipitation InnateDB
LGALS1 POU2AF1 16565088 23180781 physical association anti tag coimmunoprecipitation InnateDB
LGALS1 LGALS3BP 11146440 23180781 physical association solid phase assay InnateDB
LGALS1 PTPRC 10490978 19635795 23180781 physical association anti tag coimmunoprecipitation,cross-linking study InnateDB
LGALS1 SPN 10490978 17015718 19635795 23180781 physical association anti tag coimmunoprecipitation,cross-linking study,surface plasmon resonance InnateDB
LGALS1 PTPRB 18838383 23180781 physical association cross-linking study InnateDB
LGALS1 MUC16 12615972 23180781 physical association pull down InnateDB
LGALS1 CD2 10642604 23180781 physical association pull down InnateDB
LGALS1 CD3E 10642604 23180781 physical association pull down InnateDB
LGALS1 CD7 10490978 23180781 physical association anti tag coimmunoprecipitation InnateDB
LGALS1 CD4 10490978 23180781 physical association pull down InnateDB
LGALS1 LGALS1 12527107 23180781 physical association pull down InnateDB
LGALS1 ITGB1 14550305 23180781 physical association cross-linking study InnateDB
LGALS1 IL7R 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
LGALS1 FAS 18288482 23180781 physical association pull down InnateDB
GTF2I LGALS1 18662664 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 LGALS1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LGALS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LGALS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LGALS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LGALS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LGALS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LGALS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LGALS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 LGALS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PTTG1 LGALS1 19351864 trascriptional regulation,stimulation inferred by curator TFlink
MYC LGALS1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000096022 LGALS1 24496460 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
VASN LGALS1 25348397 N/A physical interaction ComPPI
SNRPB LGALS1 25348397 N/A physical interaction ComPPI
LGALS3 LGALS1 25348397 N/A physical interaction ComPPI
CDC42 LGALS1 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NPM1 LGALS1 25348397 N/A physical interaction ComPPI
PCBP1 LGALS1 25348397 N/A physical interaction ComPPI
CLNS1A LGALS1 25348397 N/A physical interaction ComPPI
MCM5 LGALS1 25348397 N/A physical interaction ComPPI
MCM2 LGALS1 25348397 N/A physical interaction ComPPI
SMN1 LGALS1 25348397 N/A physical interaction ComPPI
RAC1 LGALS1 25348397 N/A physical interaction ComPPI
RAB10 LGALS1 25348397 N/A physical interaction ComPPI
CD44 LGALS1 25348397 N/A physical interaction ComPPI
CD4 LGALS1 10490978 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HRAS LGALS1 11709720 14525934 22696230 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PECAM1 LGALS1 25348397 N/A physical interaction ComPPI
SLAMF1 LGALS1 25348397 N/A physical interaction ComPPI
FLT1 LGALS1 24234451 24529377 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KDR LGALS1 24234451 24529377 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescent resonance energy transfer ComPPI,IntAct
CD2 LGALS1 25348397 N/A physical interaction,in vitro ComPPI
ITGB1 LGALS1 14550305 25348397 27898060 N/A in vitro ComPPI,OmniPath
FLNA LGALS1 25348397 N/A physical interaction ComPPI
U2AF2 LGALS1 25348397 N/A physical interaction ComPPI
GTF2I LGALS1 25348397 N/A physical interaction ComPPI
YWHAZ LGALS1 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
CD7 LGALS1 10490978 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SERPINH1 LGALS1 25348397 N/A physical interaction ComPPI
UBE2N LGALS1 25348397 N/A physical interaction ComPPI
PTPRA LGALS1 25348397 N/A physical interaction ComPPI
HSPA5 LGALS1 25348397 N/A physical interaction ComPPI
MYC LGALS1 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SIGLEC7 LGALS1 25348397 N/A physical interaction ComPPI
LASP1 LGALS1 25348397 N/A physical interaction ComPPI
HNRNPL LGALS1 25348397 N/A physical interaction ComPPI
ANG LGALS1 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6AP2 LGALS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP4 LGALS1 25348397 N/A physical interaction ComPPI
GEMIN2 LGALS1 25348397 N/A physical interaction ComPPI
ANXA11 LGALS1 25348397 N/A physical interaction ComPPI
EGFR LGALS1 25348397 N/A physical interaction ComPPI
CD8A LGALS1 10490978 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPRC LGALS1 10369126 24234451 25348397 N/A affinity chromatography technology,physical interaction,enzymatic study,in vitro,in vivo ComPPI,IntAct
ANXA2 LGALS1 25348397 N/A physical interaction ComPPI
PHB2 LGALS1 25348397 N/A physical interaction ComPPI
FUBP1 LGALS1 25348397 N/A physical interaction ComPPI
PTEN LGALS1 25348397 N/A physical interaction ComPPI
VCAM1 LGALS1 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 LGALS1 25348397 N/A physical interaction ComPPI
IGBP1 LGALS1 25348397 N/A physical interaction ComPPI
NLGN3 LGALS1 25348397 N/A physical interaction ComPPI
PLIN3 LGALS1 25348397 N/A physical interaction ComPPI
VIPR2 LGALS1 25348397 N/A physical interaction ComPPI
LMAN1 LGALS1 25348397 N/A physical interaction ComPPI
SLAMF7 LGALS1 25348397 N/A physical interaction ComPPI
SPN LGALS1 10490978 14525934 17015718 19635795 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
EREG LGALS1 25348397 N/A physical interaction ComPPI
PCBP2 LGALS1 25348397 N/A physical interaction ComPPI
S1PR2 LGALS1 25348397 N/A physical interaction ComPPI
RAE1 LGALS1 25348397 N/A physical interaction ComPPI
ARF4 LGALS1 25348397 N/A physical interaction ComPPI
EFNB3 LGALS1 25348397 N/A physical interaction ComPPI
TALDO1 LGALS1 25348397 N/A physical interaction ComPPI
SOD1 LGALS1 25348397 N/A physical interaction ComPPI
DDX19B LGALS1 25348397 N/A physical interaction ComPPI
RAB5C LGALS1 25348397 N/A physical interaction ComPPI
VPREB1 LGALS1 12271131 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
ICOSLG LGALS1 25348397 N/A physical interaction ComPPI
PTGER3 LGALS1 25348397 N/A physical interaction ComPPI
MYH9 LGALS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ICAM2 LGALS1 25348397 N/A physical interaction ComPPI
LGALS1 LGALS3BP 11146440 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LGALS1 MUC16 12615972 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
LGALS1 SUSD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
LGALS1 GEMIN4 11522829 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
LGALS1 ALDOA 25348397 N/A physical interaction ComPPI
LGALS1 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
LGALS1 ACO1 25348397 N/A physical interaction ComPPI
LGALS1 APEX1 25348397 N/A physical interaction ComPPI
LGALS1 H2BC17 25348397 N/A physical interaction ComPPI
LGALS1 PSMG1 25348397 N/A physical interaction ComPPI
LGALS1 CD68 25348397 N/A physical interaction ComPPI
LGALS1 PSG1 25348397 N/A physical interaction ComPPI
LGALS1 HEPACAM2 25348397 N/A physical interaction ComPPI
LGALS1 ANXA2P2 25348397 N/A physical interaction ComPPI
LGALS1 CHORDC1 25348397 N/A physical interaction ComPPI
LGALS1 CRIP1 25348397 N/A physical interaction ComPPI
LGALS1 UQCRFS1 25348397 N/A physical interaction ComPPI
LGALS1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
LGALS1 DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LGALS1 GOLT1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LGALS1 LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LGALS1 ZNF131 25348397 N/A physical interaction ComPPI
LGALS1 ALCAM 24234451 24945728 25348397 physical association pull down,physical interaction,competition binding,enzyme linked immunosorbent assay ComPPI,IntAct
LGALS1 LINGO2 25348397 N/A physical interaction ComPPI
LGALS1 CDHR5 25348397 N/A physical interaction ComPPI
LGALS1 NTRK3 25348397 N/A physical interaction ComPPI
LGALS1 LAMP1 25348397 N/A physical interaction ComPPI
LGALS1 TYW3 25348397 N/A physical interaction ComPPI
LGALS1 CHL1 25348397 N/A physical interaction ComPPI
LGALS1 FZD10 25348397 N/A physical interaction ComPPI
LGALS1 CYLD 25348397 N/A physical interaction ComPPI
LGALS1 CD6 24234451 24945728 25348397 N/A pull down,enzyme linked immunosorbent assay ComPPI,IntAct
LRFN4 LGALS1 25348397 N/A physical interaction ComPPI
LGALS1 MZF1 24234451 30021884 physical association cross-linking study IntAct
LGALS1 ITGA3 24234451 30021884 physical association cross-linking study IntAct
LGALS1 PTPRB 18838383 27898060 N/A N/A OmniPath
LGALS1 POU2AF1 16565088 27898060 N/A N/A OmniPath
IL7R LGALS1 20167604 27898060 N/A N/A OmniPath
LGALS1 FAS 18288482 27898060 N/A N/A OmniPath

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