Gene Information gene info

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GENE：PCGF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PCGF2
FullNmae polycomb group ring finger 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12929
EnsembleID ENSG00000277258
Uniprot P35227

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PCGF2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PCGF2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PCGF2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PCGF2 GO:0000122,GO:0000122,GO:0000785,GO:0001701,GO:0001739,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006338,GO:0009952,GO:0016604,GO:0031519,GO:0035102,GO:0035102,GO:0046872,GO:0048704,GO:0070301,GO:0097190,GO:1990841,GO:2001234

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PCGF2 hsa:7703 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)
PCGF2 hsa:7703 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PCGF2 RNF2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
PCGF2 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
URS00000CBE63 PCGF2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001C3AC1 PCGF2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000012930C PCGF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 PCGF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED PCGF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB PCGF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA PCGF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 PCGF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F PCGF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000306C70 PCGF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 PCGF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000009262D PCGF2 25416803 27542229 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
UBE2I PCGF2 25348397 N/A physical interaction ComPPI
CBX8 PCGF2 19636380 20601937 21282530 24234451 25348397 27705803 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
PCBP1 PCGF2 25348397 N/A physical interaction ComPPI
EMD PCGF2 25348397 N/A physical interaction ComPPI
E2F6 PCGF2 11171983 24234451 25348397 physical association coimmunoprecipitation ComPPI,IntAct
LMNA PCGF2 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
BMI1 PCGF2 20601937 24234451 25348397 colocalization,association cosedimentation,cosedimentation in solution,molecular sieving,physical interaction ComPPI,IntAct
RING1 PCGF2 19636380 20601937 22493164 24234451 25348397 27705803 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach ComPPI,IntAct
RYBP PCGF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PHC2 PCGF2 12034499 12183370 16024804 19636380 20601937 22325352 24234451 25348397 25416956 27705803 27898060 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
PCGF2 RNF2 12183370 14525934 15741318 17296600 17936708 19636380 20471950 20601937 22325148 22325352 22493164 22844243 24234451 24457600 25348397 26151332 27705803 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,tandem affinity purification,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct,OmniPath
PCGF2 CCND2 14525934 16182291 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,fluorescence microscopy,two hybrid ComPPI,HPRD,IntAct,OmniPath
PCGF2 UBE2Q2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF2 UBE2T 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF2 UBE2U 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF2 PHC1 19636380 20601937 23523425 24234451 25348397 27705803 association,physical association physical interaction,two hybrid array,lambda repressor two hybrid,tandem affinity purification,two hybrid prey pooling approach ComPPI,IntAct
PCGF2 PHC3 19636380 20601937 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF2 CBX4 19636380 20601937 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF2 CBX2 19636380 20601937 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF2 CBX7 19636380 21282530 24234451 25348397 27705803 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
PCGF2 SPDEF 25348397 N/A physical interaction ComPPI
PCGF2 USP7 20601937 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
PCGF2 USP11 20601937 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
PCGF2 ELAVL1 25348397 N/A physical interaction ComPPI
PCGF2 YAF2 20601937 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF2 SCMH1 25348397 N/A physical interaction ComPPI
PCGF2 SCML1 25348397 N/A physical interaction ComPPI
PCGF2 HSF2 25348397 N/A physical interaction ComPPI
PCGF2 HSF1 25348397 N/A physical interaction ComPPI
PCGF2 RANGAP1 25348397 N/A physical interaction ComPPI
PCGF2 LMNB1 25348397 N/A physical interaction ComPPI
PCGF2 TMPO 25348397 N/A physical interaction ComPPI
PCGF2 TMPO 25348397 N/A physical interaction ComPPI
PCGF2 EGF 25348397 N/A physical interaction ComPPI
PCGF2 HIF1A 21602890 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCGF2 VHL 21602890 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCGF2 CBX6 21282530 24234451 25348397 27705803 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
PCGF2 YY1 25348397 N/A physical interaction ComPPI
PCGF2 RBCK1 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF2 CTNNAL1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF2 CD247 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF2 GJB5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF2 ABHD6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF2 EED 25348397 N/A physical interaction ComPPI
PCGF2 UBE2D3 25348397 N/A physical interaction ComPPI
PCGF2 BCOR 25348397 N/A physical interaction ComPPI
PCGF2 NANOGP8 25348397 N/A physical interaction ComPPI
PCGF2 NANOG 25348397 N/A physical interaction ComPPI
PCGF2 BCORL1 25348397 N/A physical interaction ComPPI
PCGF2 KLHL25 25348397 N/A physical interaction ComPPI
PCGF2 TPM2 25348397 N/A physical interaction ComPPI
PCGF2 NFS1 25348397 N/A physical interaction ComPPI
PCGF2 GOPC 25348397 N/A physical interaction ComPPI
PCGF2 PDP1 25348397 N/A physical interaction ComPPI
PCGF2 LTV1 25348397 N/A physical interaction ComPPI
PCGF2 LANCL2 25348397 N/A physical interaction ComPPI
PCGF2 ENDOG 25348397 N/A physical interaction ComPPI
PCGF2 MOV10 20543829 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCGF2 UBC 20601937 24234451 25348397 association,physical association pull down,tandem affinity purification ComPPI,IntAct
PCGF2 CPVL 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PCGF2 TUBA1C 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PCGF2 TRAF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E2 PCGF2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HOXC9 PCGF2 25348397 N/A physical interaction ComPPI
PCGF2 UBE2I 18211895 19727227 27898060 inhibition N/A OmniPath
PCGF2 HSF2 18211895 27898060 inhibition N/A OmniPath

Visualization










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