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GENE：PSIP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSIP1
FullNmae PC4 and SRSF1 interacting protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9527
EnsembleID ENSG00000164985
Uniprot O75475

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSIP1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSIP1 GO:0000395,GO:0000791,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006338,GO:0006979,GO:0009408,GO:0097100

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSIP1 hsa:11168 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 PSIP1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PSIP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 PSIP1 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 PSIP1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PSIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PSIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PSIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PSIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PSIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PSIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PSIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HDAC1 PSIP1 23386123 trascriptional regulation,stimulation inferred by curator TFlink
SP1 PSIP1 22019592 23386123 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 PSIP1 22019592 23386123 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 PSIP1 20304954 23622248 25416803 mrna cleavage,inhibition array technology,clash TarBase
URS00000ED600 PSIP1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 PSIP1 18668040 23028330 25416803 26497687 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CDC7 PSIP1 22135298 phosphorylation N/A PhosphoSite
HCFC1 PSIP1 25361965 interaction type N/A PTMCode2
PSIP1 HCFC1 25361965 interaction type N/A PTMCode2
BANF1 PSIP1 25361965 interaction type N/A PTMCode2
PSIP1 BANF1 25361965 interaction type N/A PTMCode2
MEN1 PSIP1 25361965 interaction type N/A PTMCode2
PSIP1 MEN1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EXOSC5 PSIP1 25348397 N/A physical interaction ComPPI
SAP18 PSIP1 25348397 N/A physical interaction ComPPI
SH3KBP1 PSIP1 25348397 N/A physical interaction ComPPI
NPM1 PSIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VIM PSIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2R1A PSIP1 25348397 N/A physical interaction ComPPI
LMNA PSIP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
U2AF1L5 PSIP1 25348397 N/A physical interaction ComPPI
KEAP1 PSIP1 25348397 N/A physical interaction ComPPI
RRS1 PSIP1 25348397 N/A physical interaction ComPPI
RPL10 PSIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SP1 PSIP1 25348397 N/A physical interaction ComPPI
CASP3 PSIP1 12181742 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
JUN PSIP1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
HCFC1 PSIP1 14525934 25348397 27898060 9822615 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
HMGA1 PSIP1 25348397 N/A filter binding,physical interaction ComPPI
SUMO1 PSIP1 22748127 24234451 25348397 27898060 colocalization,association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
RPA1 PSIP1 25348397 N/A physical interaction ComPPI
SUB1 PSIP1 25348397 N/A physical interaction ComPPI
CASP7 PSIP1 12181742 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CSNK2A1 PSIP1 25348397 N/A physical interaction,protein kinase assay ComPPI
MAPK6 PSIP1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EWSR1 PSIP1 25348397 N/A physical interaction ComPPI
RPA2 PSIP1 25348397 N/A physical interaction ComPPI
RPA3 PSIP1 25348397 N/A physical interaction ComPPI
RBBP8 PSIP1 22773103 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABCE1 PSIP1 25348397 N/A physical interaction ComPPI
SRSF1 PSIP1 14525934 25348397 27898060 9885563 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
SON PSIP1 25348397 N/A physical interaction ComPPI
BANF1 PSIP1 25348397 N/A physical interaction ComPPI
SUPT16H PSIP1 25348397 N/A physical interaction ComPPI
NCSTN PSIP1 25348397 N/A physical interaction ComPPI
TPBG PSIP1 25348397 N/A physical interaction ComPPI
PSIP1 MEN1 18598942 22327296 24234451 25348397 27898060 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
PSIP1 KMT2A 22327296 24234451 25348397 physical association molecular sieving,x-ray crystallography,physical interaction ComPPI,IntAct
PSIP1 HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSIP1 CAST 25348397 N/A physical interaction ComPPI
PSIP1 RPS24 25348397 N/A physical interaction ComPPI
PSIP1 EXOSC4 25348397 N/A physical interaction ComPPI
PSIP1 RPL6 25348397 N/A physical interaction ComPPI
PSIP1 FTSJ3 25348397 N/A physical interaction ComPPI
PSIP1 TRA2B 25348397 N/A physical interaction ComPPI
PSIP1 ZC3H18 25348397 N/A physical interaction ComPPI
PSIP1 RPS11 25348397 N/A physical interaction ComPPI
PSIP1 THRAP3 25348397 N/A physical interaction ComPPI
PSIP1 U2AF1 25348397 N/A physical interaction ComPPI
PSIP1 ESR1 21182205 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
PSIP1 HMGA2 25348397 N/A physical interaction ComPPI
PSIP1 CUL7 25348397 N/A physical interaction ComPPI
PSIP1 OBSL1 25348397 N/A physical interaction ComPPI
PSIP1 RBPJ 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PSIP1 FOXE1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PSIP1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PSIP1 POU5F1 25348397 N/A physical interaction ComPPI
PSIP1 FOXA1 25348397 N/A physical interaction ComPPI
PSIP1 KMT2B 23995757 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3C1 PSIP1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EIF4A3 PSIP1 25348397 N/A physical interaction ComPPI
METTL14 PSIP1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
HSPA8 PSIP1 24234451 30021884 physical association cross-linking study IntAct
GDF5 PSIP1 24234451 30021884 physical association cross-linking study IntAct
PSIP1 IGHMBP2 24234451 30021884 physical association cross-linking study IntAct
PSIP1 TMEM214 24234451 30021884 physical association cross-linking study IntAct
PSIP1 SCAF11 24234451 30021884 physical association cross-linking study IntAct
PSIP1 PPP1R13B 24234451 30021884 physical association cross-linking study IntAct
CASP3 PSIP1 12181742 18708362 27898060 inhibition N/A OmniPath
PSIP1 GCLC 16403949 27898060 stimulant N/A OmniPath
PSIP1 ADH1A 15238362 27898060 stimulant N/A OmniPath
TNF PSIP1 16403949 27898060 stimulant N/A OmniPath
PSIP1 CRYAB 11350077 27898060 stimulant N/A OmniPath
PSIP1 PRDX6 11677226 27898060 stimulant N/A OmniPath
PSIP1 HSPB1 11350077 27898060 stimulant N/A OmniPath
PSIP1 ALDH1A2 15238362 27898060 stimulant N/A OmniPath
CDC7 PSIP1 27898060 7231784 stimulant N/A OmniPath
PSIP1 ADH4 15238362 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B7398 PSIP1 27087310 direct interaction,inhibition N/A NPInter

Visualization










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