Gene Information gene info

GENE:TMPRSS6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMPRSS6
FullNmae transmembrane serine protease 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16517
EnsembleID ENSG00000187045
Uniprot Q8IU80

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMPRSS6 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMPRSS6 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TMPRSS6 GO:0000122,GO:0004222,GO:0004252,GO:0005515,GO:0005615,GO:0005886,GO:0005886,GO:0005886,GO:0006879,GO:0022617,GO:0030509,GO:0030514,GO:0030574,GO:0033619,GO:0045892,GO:0045944,GO:0060586,GO:0097264

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CEBPA TMPRSS6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TMPRSS6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TMPRSS6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TMPRSS6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TMPRSS6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 TMPRSS6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TMPRSS6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TMPRSS6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 TMPRSS6 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00004DEA91 TMPRSS6 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 TMPRSS6 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HNRNPL TMPRSS6 25348397 N/A physical interaction ComPPI
LAMA1 TMPRSS6 12149247 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL1A1 TMPRSS6 12149247 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TMPRSS6 HJV 20704562 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
TMPRSS6 FN1 12149247 14525934 N/A experimental interaction detection HPRD

Visualization