GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
TMPRSS6 |
FullNmae |
transmembrane serine protease 6 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:16517 |
EnsembleID |
ENSG00000187045 |
Uniprot |
Q8IU80 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
TMPRSS6 |
mpt |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
TMPRSS6 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
TMPRSS6 |
GO:0000122,GO:0004222,GO:0004252,GO:0005515,GO:0005615,GO:0005886,GO:0005886,GO:0005886,GO:0006879,GO:0022617,GO:0030509,GO:0030514,GO:0030574,GO:0033619,GO:0045892,GO:0045944,GO:0060586,GO:0097264 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CEBPA |
TMPRSS6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
TMPRSS6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F1 |
TMPRSS6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
TMPRSS6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
TMPRSS6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
GATA2 |
TMPRSS6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
TMPRSS6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
ZNF263 |
TMPRSS6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS000003ABC4 |
TMPRSS6 |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS00004DEA91 |
TMPRSS6 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005FDCD1 |
TMPRSS6 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
HNRNPL |
TMPRSS6 |
25348397
|
N/A |
physical interaction |
ComPPI |
LAMA1 |
TMPRSS6 |
12149247
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
COL1A1 |
TMPRSS6 |
12149247
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
TMPRSS6 |
HJV |
20704562
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
TMPRSS6 |
FN1 |
12149247
14525934
|
N/A |
experimental interaction detection |
HPRD |
Visualization