GENE:WEE1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | WEE1 |
FullNmae | WEE1 G2 checkpoint kinase |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:12761 |
EnsembleID | ENSG00000166483 |
Uniprot | P30291 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
WEE1 | mitotic_cd | 37292855 | WEE1 inhibition in cancer cells with high levels of replication stress results in induction of replication catastrophe and mitotic catastrophe. | retulator signature |
WEE1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
WEE1 | GO:0000086,GO:0000226,GO:0000287,GO:0004713,GO:0004713,GO:0004715,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0006468,GO:0016310,GO:0030010,GO:0048812,GO:0051301,GO:2000134 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
WEE1 | hsa:7465 | path:hsa04110 | Cell cycle - Homo sapiens (human) |
WEE1 | hsa:7465 | path:hsa05170 | Human immunodeficiency virus 1 infection - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | WEE1 | 16281084 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
E2F4 | WEE1 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
ESR1 | WEE1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
ETS1 | WEE1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | WEE1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | WEE1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA3 | WEE1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXA1 | WEE1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | WEE1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
PRDM14 | WEE1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | WEE1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
KDM4B | WEE1 | 20682797 | trascriptional regulation,stimulation | inferred by curator | TFlink |
KLF2 | WEE1 | 15735666 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00000600E6 | WEE1 | 21283765 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS0000338542 | WEE1 | 20584899 | rna interference,inhibition | experimental interaction detection | miRSponge |
URS00002075FA | WEE1 | 21283765 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS000040EE1D | WEE1 | 19823043 \N | rna interference,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS0000042E1F | WEE1 | 21283765 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS00000F0F49 | WEE1 | 19956200 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS00000F6E49 | WEE1 | 19956200 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS000040EE1D | WEE1 | 18927107 19823043 20371350 21572407 22847610 25416803 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay | miR2Disease,TarBase |
URS00000F6E49 | WEE1 | 19956200 20371350 21572407 25416803 | mrna cleavage,inhibition | clip,miRNA interference luciferase reporter assay | TarBase |
URS00000F0F49 | WEE1 | 19956200 20371350 21572407 23622248 23778472 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,clash,miRNA interference luciferase reporter assay | TarBase |
URS00002075FA | WEE1 | 21283765 22473208 23446348 23622248 25416803 | mrna cleavage,inhibition | clip,clash,miRNA interference luciferase reporter assay | TarBase |
URS0000042E1F | WEE1 | 21283765 22473208 23446348 25416803 | mrna cleavage,inhibition | clip,miRNA interference luciferase reporter assay | TarBase |
URS00000600E6 | WEE1 | 21283765 22473208 23446348 25416803 | mrna cleavage,inhibition | clip,miRNA interference luciferase reporter assay | TarBase |
URS00001B341F | WEE1 | 21358821 23592263 25416803 26701625 | mrna cleavage,inhibition | experimental interaction detection,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS0000330617 | WEE1 | 21358821 23592263 25416803 26701625 | mrna cleavage,inhibition | experimental interaction detection,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS00002C0FCB | WEE1 | 20371350 23622248 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clash | TarBase |
URS0000338542 | WEE1 | 20584899 23807165 25416803 | mrna cleavage,inhibition | array technology,experimental interaction detection | TarBase |
URS0000170CF4 | WEE1 | 20371350 23630541 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS000016D2D4 | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00005651EE | WEE1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000021D7C8 | WEE1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000039E1E1 | WEE1 | 23446348 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
URS000007D64A | WEE1 | 20371350 21572407 23531080 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS00001FFA8C | WEE1 | 23446348 23778472 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS000075ABF4 | WEE1 | 20371350 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003FBC84 | WEE1 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000076B539 | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000324096 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002F8148 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000DDD35 | WEE1 | 22473208 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000122ED0 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000070CD2 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000346991 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000027080C | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041E949 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000508C13 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002B3783 | WEE1 | 22473208 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003BD367 | WEE1 | 23446348 24194606 25416803 | mrna cleavage,inhibition | clip,miRNA interference luciferase reporter assay | TarBase |
URS0000298BA3 | WEE1 | 22473208 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000021D08 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002ED720 | WEE1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004F24A9 | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002E1509 | WEE1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000136174 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000004BACE | WEE1 | 23446348 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00005E1A16 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000140295 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000171CD1 | WEE1 | 20371350 21572407 25416803 25594541 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS000013ABA3 | WEE1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000041CB9C | WEE1 | 20371350 21572407 25416803 25594541 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS00000821E0 | WEE1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000040FA88 | WEE1 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EFEC1 | WEE1 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000058276F | WEE1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000080D0A | WEE1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000284586 | WEE1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075AB35 | WEE1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000475586 | WEE1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000060AABB | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004959F4 | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000034B6F5 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004CD810 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000008AA34 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000427B68 | WEE1 | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003A5E54 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000043D2C1 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002C02E4 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000118224 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000048B5E9 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000017CCCB | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000ECE9C | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000024B619 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002AB575 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075D860 | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000027352D | WEE1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000170D8B | WEE1 | 23446348 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000065FDF | WEE1 | 20371350 22012620 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000024CEE0 | WEE1 | 20371350 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001925C1 | WEE1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004719AB | WEE1 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
URS000075CC78 | WEE1 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
URS0000045DBD | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002DD349 | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000183BED | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001CC864 | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000315338 | WEE1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000070B1D | WEE1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000031602A | WEE1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000047A67D | WEE1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003AFAD1 | WEE1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000078918 | WEE1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005ACA7C | WEE1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000EE7F0 | WEE1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003B59DF | WEE1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000020579D | WEE1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001481F9 | WEE1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS000075BDAA | WEE1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS00000EC1BE | WEE1 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CSNK2A1 | WEE1 | 22135298 | phosphorylation | N/A | PhosphoSite |
CSNK1D | WEE1 | 22135298 | phosphorylation | N/A | PhosphoSite |
CDK1 | WEE1 | 22135298 | phosphorylation | N/A | PhosphoSite |
GSK3B | WEE1 | 22135298 | phosphorylation | N/A | PhosphoSite |
PLK1 | WEE1 | 22135298 | phosphorylation | N/A | PhosphoSite |
WEE1 | HSP90AA1 | 22135298 | phosphorylation | N/A | PhosphoSite |
WEE1 | CDK2 | 22135298 | phosphorylation | N/A | PhosphoSite |
WEE1 | CDK1 | 22135298 | phosphorylation | N/A | PhosphoSite |
AKT1 | WEE1 | 22135298 | phosphorylation | N/A | PhosphoSite |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PIN1 | WEE1 | 25348397 | N/A | physical interaction | ComPPI |
CDCA3 | WEE1 | 12679038 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
PCBP1 | WEE1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
YWHAG | WEE1 | 14525934 15324660 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,in vivo | ComPPI,HPRD,IntAct |
MCM2 | WEE1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CRK | WEE1 | 11839808 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
CBY1 | WEE1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CASP3 | WEE1 | 14525934 25348397 9618490 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
SMAD3 | WEE1 | 14525934 15761153 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
PAXIP1 | WEE1 | 25348397 | N/A | physical interaction | ComPPI |
YWHAB | WEE1 | 10775038 14525934 15324660 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
YWHAZ | WEE1 | 14525934 15161933 24234451 25348397 | physical association | experimental interaction detection,far western blotting,pull down,in vitro | ComPPI,HPRD,IntAct |
BTRC | WEE1 | 14525934 15070733 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
PLK1 | WEE1 | 14525934 15070733 24234451 25348397 | phosphorylation reaction | experimental interaction detection,physical interaction,kinase homogeneous time resolved fluorescence,in vitro | ComPPI,HPRD,IntAct |
CSNK2A1 | WEE1 | 14525934 16085715 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
H2BC21 | WEE1 | 22885324 24234451 25348397 | phosphorylation reaction | phosphorylation reaction,protein kinase assay | ComPPI,IntAct |
XPO1 | WEE1 | 25348397 | N/A | physical interaction | ComPPI |
YWHAQ | WEE1 | 25348397 | N/A | physical interaction | ComPPI |
BRD8 | WEE1 | 14525934 15070733 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
ARRB2 | WEE1 | 17620599 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SPTBN1 | WEE1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDK2 | WEE1 | 14525934 25348397 7743995 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
BCR | WEE1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
SFN | WEE1 | 15778465 24234451 25348397 | physical association | physical interaction,tandem affinity purification | ComPPI,IntAct |
WEE1 | SKP2 | 14525934 15070733 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
WEE1 | BRSK1 | 14525934 15150265 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
WEE1 | BRSK2 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
WEE1 | FBXW11 | 14525934 15070733 16085715 24234451 25241761 25348397 | association,physical association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
WEE1 | SMURF1 | 14525934 15761153 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
WEE1 | NEDD4 | 25348397 | N/A | physical interaction | ComPPI |
WEE1 | CSNK2B | 25348397 | N/A | physical interaction | ComPPI |
WEE1 | CDK1 | 10564259 12186947 14525934 25348397 8428596 9268380 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
WEE1 | CNBP | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
WEE1 | EEF2 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
WEE1 | YEATS4 | 25348397 | N/A | physical interaction | ComPPI |
WEE1 | NUP160 | 25348397 | N/A | physical interaction | ComPPI |
WEE1 | RUSC2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
WEE1 | CEP350 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
WEE1 | WDFY3 | 25348397 | N/A | physical interaction | ComPPI |
WEE1 | BRPF3 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
WEE1 | CCNYL1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
WEE1 | CSNK1A1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
WEE1 | KCTD3 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
WEE1 | USP15 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
WEE1 | KIF13B | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
WEE1 | SPAG9 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
WEE1 | MCM4 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
WEE1 | CGN | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
WEE1 | DENND4C | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
WEE1 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
WEE1 | NPAT | 22885324 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
WEE1 | NEK6 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
MUS81 | WEE1 | 25348397 | N/A | physical interaction | ComPPI |
BSK | WEE1 | 14605208 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
WEE1 | WEE1 | 14525934 17192257 | N/A | experimental interaction detection | HPRD |
VIM | WEE1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
WEE1 | CDS1 | 11606526 21099360 27898060 9572736 | N/A | N/A | OmniPath |
WEE1 | CDR1 | 23615447 27898060 8515817 8515818 9928955 | N/A | N/A | OmniPath |
PLK1 | WEE1 | 15070733 15350223 16085715 18285803 27898060 | inhibition,stimulant | N/A | OmniPath |
CHEK1 | WEE1 | 15070733 19500427 20068082 27898060 7681363 8515817 | inhibition,stimulant | N/A | OmniPath |
CDK2 | WEE1 | 11029659 16085715 27898060 7743995 | inhibition | N/A | OmniPath |
WEE1 | CDK2 | 11029659 11298456 12181445 12912980 13678583 1396589 14551212 15136770 15632290 16085715 16497976 16546994 17016520 17095507 17192257 17283158 17389395 17545210 18083107 18212344 18276582 18452278 18491316 18691976 18776048 18927589 19369195 19410646 19534553 19664994 19690332 19838212 20068230 20368335 21403953 21447384 22179839 23671119 23840880 25171405 25278378 26240362 27898060 7743995 9038181 | inhibition,stimulant | N/A | OmniPath |
WEE1 | SKP1 | 18285803 27898060 | stimulant | N/A | OmniPath |
WEE1 | AKT1 | 15964826 27898060 | N/A | N/A | OmniPath |
AKT1 | WEE1 | 15150265 15964826 21389100 27898060 | N/A | N/A | OmniPath |
WEE1 | HSP90AA1 | 20159553 27898060 | N/A | N/A | OmniPath |
CDK1 | WEE1 | 10564259 12186947 15070733 16085715 16096060 16698944 18285803 23051732 27898060 7743995 8428596 9268380 | inhibition,stimulant | N/A | OmniPath |
WEE1 | CDK1 | 10564259 12186947 15070733 16085715 16096060 16497976 16698944 17016520 18285803 18452278 18669648 18691976 19413330 19415658 19651622 19901323 20058876 20068231 27898060 7743995 8084605 8428596 9268380 | inhibition | N/A | OmniPath |
PAK1 | WEE1 | 15037762 27898060 | inhibition | N/A | OmniPath |
CSNK2A1 | WEE1 | 16085715 18560763 27898060 | N/A | N/A | OmniPath |
CSNK2B | WEE1 | 18469858 18560763 27898060 | inhibition,stimulant | N/A | OmniPath |
DAPK1 | WEE1 | 15150265 15964826 27898060 | N/A | N/A | OmniPath |
CDCA3 | WEE1 | 12679038 15733861 27898060 | inhibition | N/A | OmniPath |
WEE1 | EIF4E | 11723111 27898060 7782323 | N/A | N/A | OmniPath |
BTRC | WEE1 | 15070733 15340381 16085715 25900982 27898060 | inhibition | N/A | OmniPath |
WEE1 | S100A9 | 2478889 27898060 | N/A | N/A | OmniPath |
BRSK2 | WEE1 | 15150265 27898060 | N/A | N/A | OmniPath |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00009B27CF | WEE1 | 27087310 | direct interaction,inhibition | N/A | NPInter |