Gene Information gene info

GENE:WEE1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WEE1
FullNmae WEE1 G2 checkpoint kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12761
EnsembleID ENSG00000166483
Uniprot P30291

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WEE1 mitotic_cd 37292855 WEE1 inhibition in cancer cells with high levels of replication stress results in induction of replication catastrophe and mitotic catastrophe. retulator signature
WEE1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
WEE1 GO:0000086,GO:0000226,GO:0000287,GO:0004713,GO:0004713,GO:0004715,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0006468,GO:0016310,GO:0030010,GO:0048812,GO:0051301,GO:2000134

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
WEE1 hsa:7465 path:hsa04110 Cell cycle - Homo sapiens (human)
WEE1 hsa:7465 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDK1 WEE1 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 23508805 23897299 26192618 7575488 9892021 interaction type N/A ACSN
PLK1 WEE1 11073952 17596790 18931676 19270156 19622404 19686080 26192618 8127874 interaction type N/A ACSN
WEE1 CDK2 15279786 17303408 17660363 18590585 23508805 23897299 26192618 7575488 interaction type N/A ACSN
CUL1 WEE1 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 WEE1 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
SKP1 WEE1 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
SKP2 WEE1 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
CHEK1 WEE1 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 19793801 23508805 23897299 26192618 interaction type N/A ACSN
AKT1 WEE1 15964826 23180781 physical association anti tag coimmunoprecipitation InnateDB
YWHAQ WEE1 15964826 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR WEE1 16281084 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
E2F4 WEE1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 WEE1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 WEE1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 WEE1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 WEE1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 WEE1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 WEE1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 WEE1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 WEE1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 WEE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
KDM4B WEE1 20682797 trascriptional regulation,stimulation inferred by curator TFlink
KLF2 WEE1 15735666 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 WEE1 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000338542 WEE1 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS00002075FA WEE1 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000040EE1D WEE1 19823043 \N rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000042E1F WEE1 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000F0F49 WEE1 19956200 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000F6E49 WEE1 19956200 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000040EE1D WEE1 18927107 19823043 20371350 21572407 22847610 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS00000F6E49 WEE1 19956200 20371350 21572407 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS00000F0F49 WEE1 19956200 20371350 21572407 23622248 23778472 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,clash,miRNA interference luciferase reporter assay TarBase
URS00002075FA WEE1 21283765 22473208 23446348 23622248 25416803 mrna cleavage,inhibition clip,clash,miRNA interference luciferase reporter assay TarBase
URS0000042E1F WEE1 21283765 22473208 23446348 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS00000600E6 WEE1 21283765 22473208 23446348 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS00001B341F WEE1 21358821 23592263 25416803 26701625 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000330617 WEE1 21358821 23592263 25416803 26701625 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00002C0FCB WEE1 20371350 23622248 25416803 mrna cleavage,inhibition nucleotide sequence identification,clash TarBase
URS0000338542 WEE1 20584899 23807165 25416803 mrna cleavage,inhibition array technology,experimental interaction detection TarBase
URS0000170CF4 WEE1 20371350 23630541 25416803 mrna cleavage,inhibition nucleotide sequence identification,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000016D2D4 WEE1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00005651EE WEE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 WEE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039E1E1 WEE1 23446348 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000007D64A WEE1 20371350 21572407 23531080 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00001FFA8C WEE1 23446348 23778472 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000075ABF4 WEE1 20371350 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 WEE1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 WEE1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 WEE1 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 WEE1 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 WEE1 23446348 24194606 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS0000298BA3 WEE1 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ED720 WEE1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 WEE1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 WEE1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE WEE1 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005E1A16 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 WEE1 20371350 21572407 25416803 25594541 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000013ABA3 WEE1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041CB9C WEE1 20371350 21572407 25416803 25594541 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000821E0 WEE1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 WEE1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 WEE1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000058276F WEE1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A WEE1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 WEE1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB35 WEE1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 WEE1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004959F4 WEE1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000034B6F5 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 WEE1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000048B5E9 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D860 WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D WEE1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B WEE1 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000065FDF WEE1 20371350 22012620 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000024CEE0 WEE1 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001925C1 WEE1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB WEE1 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS000075CC78 WEE1 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS0000045DBD WEE1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002DD349 WEE1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED WEE1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 WEE1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 WEE1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D WEE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A WEE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D WEE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 WEE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 WEE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C WEE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 WEE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF WEE1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D WEE1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001481F9 WEE1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075BDAA WEE1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000EC1BE WEE1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 WEE1 22135298 phosphorylation N/A PhosphoSite
CSNK1D WEE1 22135298 phosphorylation N/A PhosphoSite
CDK1 WEE1 22135298 phosphorylation N/A PhosphoSite
GSK3B WEE1 22135298 phosphorylation N/A PhosphoSite
PLK1 WEE1 22135298 phosphorylation N/A PhosphoSite
WEE1 HSP90AA1 22135298 phosphorylation N/A PhosphoSite
WEE1 CDK2 22135298 phosphorylation N/A PhosphoSite
WEE1 CDK1 22135298 phosphorylation N/A PhosphoSite
AKT1 WEE1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PIN1 WEE1 25348397 N/A physical interaction ComPPI
CDCA3 WEE1 12679038 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PCBP1 WEE1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAG WEE1 14525934 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
MCM2 WEE1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CRK WEE1 11839808 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBY1 WEE1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CASP3 WEE1 14525934 25348397 9618490 N/A experimental interaction detection,in vitro ComPPI,HPRD
SMAD3 WEE1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PAXIP1 WEE1 25348397 N/A physical interaction ComPPI
YWHAB WEE1 10775038 14525934 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
YWHAZ WEE1 14525934 15161933 24234451 25348397 physical association experimental interaction detection,far western blotting,pull down,in vitro ComPPI,HPRD,IntAct
BTRC WEE1 14525934 15070733 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PLK1 WEE1 14525934 15070733 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,kinase homogeneous time resolved fluorescence,in vitro ComPPI,HPRD,IntAct
CSNK2A1 WEE1 14525934 16085715 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
H2BC21 WEE1 22885324 24234451 25348397 phosphorylation reaction phosphorylation reaction,protein kinase assay ComPPI,IntAct
XPO1 WEE1 25348397 N/A physical interaction ComPPI
YWHAQ WEE1 25348397 N/A physical interaction ComPPI
BRD8 WEE1 14525934 15070733 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ARRB2 WEE1 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPTBN1 WEE1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2 WEE1 14525934 25348397 7743995 N/A experimental interaction detection,in vitro ComPPI,HPRD
BCR WEE1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SFN WEE1 15778465 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
WEE1 SKP2 14525934 15070733 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
WEE1 BRSK1 14525934 15150265 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
WEE1 BRSK2 25348397 N/A physical interaction,in vitro ComPPI
WEE1 FBXW11 14525934 15070733 16085715 24234451 25241761 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
WEE1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
WEE1 NEDD4 25348397 N/A physical interaction ComPPI
WEE1 CSNK2B 25348397 N/A physical interaction ComPPI
WEE1 CDK1 10564259 12186947 14525934 25348397 8428596 9268380 N/A experimental interaction detection,physical interaction ComPPI,HPRD
WEE1 CNBP 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WEE1 EEF2 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WEE1 YEATS4 25348397 N/A physical interaction ComPPI
WEE1 NUP160 25348397 N/A physical interaction ComPPI
WEE1 RUSC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WEE1 CEP350 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WEE1 WDFY3 25348397 N/A physical interaction ComPPI
WEE1 BRPF3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WEE1 CCNYL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WEE1 CSNK1A1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WEE1 KCTD3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WEE1 USP15 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WEE1 KIF13B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WEE1 SPAG9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WEE1 MCM4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WEE1 CGN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WEE1 DENND4C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
WEE1 TRIM25 25348397 N/A physical interaction ComPPI
WEE1 NPAT 22885324 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
WEE1 NEK6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MUS81 WEE1 25348397 N/A physical interaction ComPPI
BSK WEE1 14605208 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WEE1 WEE1 14525934 17192257 N/A experimental interaction detection HPRD
VIM WEE1 24234451 30021884 physical association cross-linking study IntAct
WEE1 CDS1 11606526 21099360 27898060 9572736 N/A N/A OmniPath
WEE1 CDR1 23615447 27898060 8515817 8515818 9928955 N/A N/A OmniPath
PLK1 WEE1 15070733 15350223 16085715 18285803 27898060 inhibition,stimulant N/A OmniPath
CHEK1 WEE1 15070733 19500427 20068082 27898060 7681363 8515817 inhibition,stimulant N/A OmniPath
CDK2 WEE1 11029659 16085715 27898060 7743995 inhibition N/A OmniPath
WEE1 CDK2 11029659 11298456 12181445 12912980 13678583 1396589 14551212 15136770 15632290 16085715 16497976 16546994 17016520 17095507 17192257 17283158 17389395 17545210 18083107 18212344 18276582 18452278 18491316 18691976 18776048 18927589 19369195 19410646 19534553 19664994 19690332 19838212 20068230 20368335 21403953 21447384 22179839 23671119 23840880 25171405 25278378 26240362 27898060 7743995 9038181 inhibition,stimulant N/A OmniPath
WEE1 SKP1 18285803 27898060 stimulant N/A OmniPath
WEE1 AKT1 15964826 27898060 N/A N/A OmniPath
AKT1 WEE1 15150265 15964826 21389100 27898060 N/A N/A OmniPath
WEE1 HSP90AA1 20159553 27898060 N/A N/A OmniPath
CDK1 WEE1 10564259 12186947 15070733 16085715 16096060 16698944 18285803 23051732 27898060 7743995 8428596 9268380 inhibition,stimulant N/A OmniPath
WEE1 CDK1 10564259 12186947 15070733 16085715 16096060 16497976 16698944 17016520 18285803 18452278 18669648 18691976 19413330 19415658 19651622 19901323 20058876 20068231 27898060 7743995 8084605 8428596 9268380 inhibition N/A OmniPath
PAK1 WEE1 15037762 27898060 inhibition N/A OmniPath
CSNK2A1 WEE1 16085715 18560763 27898060 N/A N/A OmniPath
CSNK2B WEE1 18469858 18560763 27898060 inhibition,stimulant N/A OmniPath
DAPK1 WEE1 15150265 15964826 27898060 N/A N/A OmniPath
CDCA3 WEE1 12679038 15733861 27898060 inhibition N/A OmniPath
WEE1 EIF4E 11723111 27898060 7782323 N/A N/A OmniPath
BTRC WEE1 15070733 15340381 16085715 25900982 27898060 inhibition N/A OmniPath
WEE1 S100A9 2478889 27898060 N/A N/A OmniPath
BRSK2 WEE1 15150265 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B27CF WEE1 27087310 direct interaction,inhibition N/A NPInter

Visualization