Gene Information gene info

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GENE：UBE2Z

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2Z
FullNmae ubiquitin conjugating enzyme E2 Z
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25847
EnsembleID ENSG00000159202
Uniprot Q9H832

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2Z lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBE2Z immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBE2Z ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBE2Z GO:0004869,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0005829,GO:0006511,GO:0006915,GO:0016567,GO:0043065,GO:0043066,GO:0060090,GO:0061631

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2Z hsa:65264 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 UBE2Z 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 UBE2Z 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 UBE2Z 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBE2Z 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UBE2Z 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBE2Z 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007FBA UBE2Z 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002FC5B0 UBE2Z 20371350 21572407 24398324 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000AA464 UBE2Z 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE UBE2Z 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D UBE2Z 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB UBE2Z 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 UBE2Z 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 UBE2Z 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD UBE2Z 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 UBE2Z 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 UBE2Z 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA UBE2Z 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 UBE2Z 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 UBE2Z 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 UBE2Z 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B7450 UBE2Z 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6479 UBE2Z 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016C318 UBE2Z 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000FB5B8 UBE2Z 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000002103A UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004E02F2 UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BD6DC UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000004BACE UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000015A0D9 UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005485E8 UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000ECE9C UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001A7A UBE2Z 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BAG3 UBE2Z 25348397 N/A physical interaction ComPPI
SMAD4 UBE2Z 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RNF5 UBE2Z 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AP1G2 UBE2Z 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMAD1 UBE2Z 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
REL UBE2Z 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP1CA UBE2Z 22321011 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GORASP2 UBE2Z 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LPL UBE2Z 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RANBP9 UBE2Z 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBR2 UBE2Z 25348397 N/A physical interaction ComPPI
XPO1 UBE2Z 25348397 N/A physical interaction ComPPI
SYVN1 UBE2Z 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRAF2 UBE2Z 19690564 24234451 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
MDM2 UBE2Z 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAPSN UBE2Z 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BMPR1B UBE2Z 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
WDR12 UBE2Z 25348397 N/A physical interaction ComPPI
TRAIP UBE2Z 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF139 UBE2Z 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PRKN UBE2Z 25348397 N/A physical interaction ComPPI
UBA1 UBE2Z 25348397 N/A physical interaction ComPPI
RNF41 UBE2Z 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSME3 UBE2Z 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TRIM27 UBE2Z 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBD UBE2Z 24234451 24528925 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HLTF UBE2Z 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LNX2 UBE2Z 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LNX1 UBE2Z 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
INCA1 UBE2Z 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DZIP3 UBE2Z 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF144B UBE2Z 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBR1 UBE2Z 25348397 N/A physical interaction ComPPI
UBE2Z SRA1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBE2Z RNF103 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2Z TRIM65 19549727 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2Z HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2Z MOV10 25348397 N/A physical interaction ComPPI
UBE2Z NXF1 25348397 N/A physical interaction ComPPI
UBE2Z GUK1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2Z CCT3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2Z TGFBR1 14525934 15761153 N/A experimental interaction detection HPRD

Visualization










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