Gene Information gene info

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GENE：MCM3AP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MCM3AP
FullNmae minichromosome maintenance complex component 3 associated protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6946
EnsembleID ENSG00000160294
Uniprot O60318

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MCM3AP ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MCM3AP GO:0003676,GO:0003682,GO:0004402,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005829,GO:0005829,GO:0006406,GO:0010484,GO:0015031,GO:0016446,GO:0016973,GO:0031965,GO:0034728,GO:0042393,GO:0044615,GO:0070390,GO:0070390

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 MCM3AP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MCM3AP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MCM3AP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MCM3AP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MCM3AP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MCM3AP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MCM3AP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 MCM3AP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE MCM3AP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 MCM3AP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001938D9 MCM3AP 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDC73 MCM3AP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDC42 MCM3AP 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TRIB3 MCM3AP 25348397 N/A physical interaction ComPPI
LMNA MCM3AP 25348397 N/A physical interaction ComPPI
RAC1 MCM3AP 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EP300 MCM3AP 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD3 MCM3AP 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
APC MCM3AP 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SMAD9 MCM3AP 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CLSTN1 MCM3AP 12421765 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MCM3AP MCM3 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
MCM3AP CRMP1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM3AP ENY2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM3AP TERF2 25348397 N/A physical interaction ComPPI
MCM3AP SUV39H2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MCM3AP SIRT7 25348397 N/A physical interaction ComPPI
MCM3AP CDC25A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MCM3AP POLR2G 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MCM3AP DDX39A 25348397 N/A physical interaction ComPPI
MCM3AP IER2 25348397 N/A physical interaction ComPPI
MCM3AP IFI16 25348397 N/A physical interaction ComPPI
MCM3AP NUP43 25348397 N/A physical interaction ComPPI
MCM3AP XPO1 25348397 N/A physical interaction ComPPI
MCM3AP BLM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM3AP KIFC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM3AP KLC4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM3AP PCID2 25348397 N/A pull down,physical interaction ComPPI
MCM3AP CELSR3 24234451 25348397 physical association two hybrid ComPPI,IntAct
CETN1 MCM3AP 25348397 N/A physical interaction ComPPI
TAF1D MCM3AP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MCM3AP PLEC 24234451 30021884 physical association cross-linking study IntAct

Visualization










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