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GENE：NNT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NNT
FullNmae nicotinamide nucleotide transhydrogenase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7863
EnsembleID ENSG00000112992
Uniprot Q13423

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NNT ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NNT GO:0001933,GO:0003957,GO:0005739,GO:0005743,GO:0005746,GO:0006099,GO:0006740,GO:0008746,GO:0010918,GO:0016020,GO:0032364,GO:0033273,GO:0043066,GO:0045454,GO:0050661,GO:0050661,GO:0051287,GO:0072593,GO:0098869,GO:1902600,GO:1903285

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NNT hsa:23530 path:hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human)
NNT hsa:23530 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NNT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 NNT 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 NNT 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000600E6 NNT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001F0C23 NNT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000028DE3F NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000285DCB NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000475586 NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000F6E49 NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000008F0CF NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000052EA98 NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EEE35 NNT 21572407 23446348 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007D64A NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000F0F49 NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000040EE1D NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041CB9C NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000171CD1 NNT 21572407 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039A052 NNT 21572407 23446348 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000076B539 NNT 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000040EC3B NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004DEA91 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004F507C NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 NNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004A9320 NNT 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATP5F1B NNT 25348397 N/A physical interaction ComPPI
SLC25A6 NNT 25348397 N/A physical interaction ComPPI
ABCD3 NNT 25348397 N/A physical interaction ComPPI
MVP NNT 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NTRK1 NNT 25348397 N/A physical interaction ComPPI
LAMTOR3 NNT 25348397 N/A physical interaction ComPPI
DCTN1 NNT 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NPHP1 NNT 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HUWE1 NNT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SF1 NNT 25348397 N/A physical interaction ComPPI
MME NNT 17342744 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL7 NNT 25348397 N/A physical interaction ComPPI
FKBP8 NNT 25348397 N/A physical interaction ComPPI
TRIM25 NNT 25348397 N/A physical interaction ComPPI
ECSIT NNT 25348397 N/A physical interaction ComPPI
NDUFS7 NNT 25348397 N/A physical interaction ComPPI
FAF2 NNT 25348397 N/A physical interaction ComPPI
PRPF3 NNT 25348397 N/A physical interaction ComPPI
HSPD1 NNT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HNRNPA1 NNT 25348397 N/A physical interaction ComPPI
POFUT1 NNT 25348397 N/A physical interaction ComPPI
NDUFS6 NNT 25348397 N/A physical interaction ComPPI
OFD1 NNT 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SIRT7 NNT 25348397 N/A physical interaction ComPPI
FBF1 NNT 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NDUFA9 NNT 25348397 N/A physical interaction ComPPI
COX6B1 NNT 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
THY1 NNT 25348397 N/A physical interaction ComPPI
NNT TIMM10 25348397 N/A physical interaction ComPPI
NNT SLAIN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NNT TENT4B 25348397 N/A physical interaction ComPPI
NNT NDUFA4 25348397 N/A physical interaction ComPPI

Visualization










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