Gene Information gene info

GENE:KDM4B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KDM4B
FullNmae lysine demethylase 4B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29136
EnsembleID ENSG00000127663
Uniprot O94953

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KDM4B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KDM4B ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KDM4B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KDM4B GO:0000785,GO:0005634,GO:0005654,GO:0006338,GO:0007420,GO:0010468,GO:0032452,GO:0032454,GO:0032454,GO:0032454,GO:0046872,GO:0051864,GO:0140684

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR KDM4B 18971253 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 KDM4B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 KDM4B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 KDM4B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A KDM4B 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 KDM4B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 KDM4B 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 KDM4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 KDM4B 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000017EA6A KDM4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 KDM4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 KDM4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001919B0 KDM4B 25416803 25725194 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
H2BC4 KDM4B 25348397 N/A physical interaction ComPPI
H4C1 KDM4B 22373579 24234451 25348397 N/A isothermal titration calorimetry ComPPI,IntAct
KMT2D KDM4B 25348397 N/A physical interaction ComPPI
HSP90B1 KDM4B 25348397 N/A physical interaction ComPPI
ASH2L KDM4B 25348397 N/A physical interaction ComPPI
HNRNPU KDM4B 25348397 N/A physical interaction ComPPI
HNRNPL KDM4B 25348397 N/A physical interaction ComPPI
UHRF2 KDM4B 25348397 N/A physical interaction ComPPI
RBBP5 KDM4B 25348397 N/A physical interaction ComPPI
TCP1 KDM4B 25348397 N/A physical interaction ComPPI
CCT5 KDM4B 25348397 N/A physical interaction ComPPI
CCT7 KDM4B 25348397 N/A physical interaction ComPPI
HSPA4 KDM4B 25348397 N/A physical interaction ComPPI
SF1 KDM4B 24234451 25348397 26420826 physical association two hybrid fragment pooling approach ComPPI,IntAct
DDX3X KDM4B 25348397 N/A physical interaction ComPPI
TRIM25 KDM4B 25348397 N/A physical interaction ComPPI
ESR1 KDM4B 25348397 N/A physical interaction ComPPI
SNU13 KDM4B 25348397 N/A physical interaction ComPPI
WDR5 KDM4B 25348397 N/A physical interaction ComPPI
CCT4 KDM4B 25348397 N/A physical interaction ComPPI
CCT2 KDM4B 25348397 N/A physical interaction ComPPI
CCT6A KDM4B 25348397 N/A physical interaction ComPPI
MED10 KDM4B 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KDM4B SMU1 25348397 N/A physical interaction ComPPI
KDM4B H2BC11 25348397 N/A physical interaction ComPPI
KDM4B KDM4A 25348397 N/A physical interaction ComPPI
KDM4B CCT3 25348397 N/A physical interaction ComPPI
KDM4B CCT8 25348397 N/A physical interaction ComPPI
KDM4B H3C1 18022353 27898060 inhibition N/A OmniPath

Visualization