GENE:KDM4B
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | KDM4B |
FullNmae | lysine demethylase 4B |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:29136 |
EnsembleID | ENSG00000127663 |
Uniprot | O94953 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
KDM4B | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
KDM4B | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
KDM4B | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
KDM4B | GO:0000785,GO:0005634,GO:0005654,GO:0006338,GO:0007420,GO:0010468,GO:0032452,GO:0032454,GO:0032454,GO:0032454,GO:0046872,GO:0051864,GO:0140684 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | KDM4B | 18971253 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
ETS1 | KDM4B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | KDM4B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | KDM4B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
HIF1A | KDM4B | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
YBX1 | KDM4B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
PRDM14 | KDM4B | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | KDM4B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | KDM4B | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000017EA6A | KDM4B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000600E6 | KDM4B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00003D5391 | KDM4B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00001919B0 | KDM4B | 25416803 25725194 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
H2BC4 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
H4C1 | KDM4B | 22373579 24234451 25348397 | N/A | isothermal titration calorimetry | ComPPI,IntAct |
KMT2D | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
HSP90B1 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
ASH2L | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
HNRNPU | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
HNRNPL | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
UHRF2 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
RBBP5 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
TCP1 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
CCT5 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
CCT7 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
HSPA4 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
SF1 | KDM4B | 24234451 25348397 26420826 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
DDX3X | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
TRIM25 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
ESR1 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
SNU13 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
WDR5 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
CCT4 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
CCT2 | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
CCT6A | KDM4B | 25348397 | N/A | physical interaction | ComPPI |
MED10 | KDM4B | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
KDM4B | SMU1 | 25348397 | N/A | physical interaction | ComPPI |
KDM4B | H2BC11 | 25348397 | N/A | physical interaction | ComPPI |
KDM4B | KDM4A | 25348397 | N/A | physical interaction | ComPPI |
KDM4B | CCT3 | 25348397 | N/A | physical interaction | ComPPI |
KDM4B | CCT8 | 25348397 | N/A | physical interaction | ComPPI |
KDM4B | H3C1 | 18022353 27898060 | inhibition | N/A | OmniPath |