Gene Information gene info

  1. Home

GENE：MRE11

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRE11
FullNmae MRE11 homolog, double strand break repair nuclease
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7230
EnsembleID ENSG00000020922
Uniprot P49959

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRE11 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRE11 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRE11 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MRE11 GO:0000014,GO:0000014,GO:0000019,GO:0000723,GO:0000724,GO:0000724,GO:0000729,GO:0000729,GO:0000781,GO:0000781,GO:0000781,GO:0003677,GO:0003678,GO:0003690,GO:0004518,GO:0004520,GO:0004520,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005657,GO:0005737,GO:0005829,GO:0006281,GO:0006302,GO:0006303,GO:0006303,GO:0006310,GO:0006974,GO:0007004,GO:0007062,GO:0007095,GO:0007129,GO:0007131,GO:0008283,GO:0008296,GO:0008408,GO:0008409,GO:0016605,GO:0016605,GO:0030145,GO:0030870,GO:0030870,GO:0030870,GO:0030870,GO:0030870,GO:0031573,GO:0031860,GO:0031954,GO:0032206,GO:0032508,GO:0033674,GO:0035825,GO:0035861,GO:0035861,GO:0042138,GO:0042802,GO:0043066,GO:0044818,GO:0045296,GO:0070533,GO:0097552,GO:0098687,GO:0110025,GO:0110025

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MRE11 hsa:4361 path:hsa03440 Homologous recombination - Homo sapiens (human)
MRE11 hsa:4361 path:hsa03450 Non-homologous end-joining - Homo sapiens (human)
MRE11 hsa:4361 path:hsa04218 Cellular senescence - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATM MRE11 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 26192618 7575488 9407949 9488723 9721205 interaction type N/A ACSN
MRE11 RAD50 10882712 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14726013 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15703371 15798197 15964794 16163361 16332722 16337602 16449207 16531125 16581787 16697054 16713580 16805667 16818604 16858402 17036055 17055429 17088286 17102137 17116323 17116881 17116885 17296725 17303408 17384638 17582221 17660363 17713585 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18677104 18678890 18716619 18809224 18931676 18995830 19151707 19202191 19208614 19217833 19270065 19282663 19342888 19357644 19362533 19364882 19490890 19622404 196269035 19654615 19686080 19772495 19793801 19793861 19793862 19805513 19841479 19847258 19892829 20021983 20027199 20029420 20051983 20064462 20603072 20691907 20713526 20723763 21060331 21270334 21337561 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22751496 22921416 23082994 23145148 23161013 23253856 23444773 23562323 23568489 23847781 24036544 24050180 24089143 24095737 24210699 24684389 24709898 24976506 26192618 7575488 9407949 9488723 9721205 interaction type N/A ACSN
WRN MRE11 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 26192618 9721205 interaction type N/A ACSN
MRE11 MDC1 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 26192618 7575488 9407949 9488723 interaction type N/A ACSN
ATR MRE11 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15798197 16713580 16805667 17102137 17116885 17296725 17384638 17582221 18087292 18469862 18584027 18677104 18809224 18931676 18995830 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 22751496 23444773 24050180 26192618 interaction type N/A ACSN
FANCD2 MRE11 10882712 11850621 11877377 12086603 12556884 12607003 14988723 15136767 15175241 15211575 15459660 15498778 15798197 15964794 16163361 16332722 16337602 16531125 16581787 16713580 16805667 16858402 17036055 17102137 17116885 17296725 17303408 17384638 17582221 17713585 17965729 18087292 18171670 18469862 18584027 18677104 18809224 18931676 18995830 19151707 19282663 19342888 19362533 19622404 19654615 19686080 19772495 19793801 19793861 19793862 19805513 19841479 19892829 20051983 20064462 20723763 21376743 22743550 22751496 23444773 24050180 24089143 24095737 26192618 interaction type N/A ACSN
BRCA1 MRE11 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 26192618 9721205 interaction type N/A ACSN
MRE11 PARP2 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 26192618 9721205 interaction type N/A ACSN
PARP1 MRE11 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 26192618 9721205 interaction type N/A ACSN
MRE11 CHEK2 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 26192618 7575488 9407949 9488723 interaction type N/A ACSN
BLM MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FAAP100 MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FAAP20 MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FAAP24 MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCA MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCB MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCC MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCE MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCG MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCL MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCM MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
HES1 MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
MRE11 ATM 10608806 23180781 phosphorylation reaction in-gel kinase assay InnateDB
MECOM MRE11 23180781 23858473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MRE11 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYCN MRE11 16093321 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
LEF1 MRE11 20956948 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF MRE11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MRE11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MRE11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MRE11 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000055128B MRE11 19141645 rna interference,inhibition western blot miRSponge
URS0000508C13 MRE11 19141645 rna interference,inhibition western blot miRSponge
URS000055128B MRE11 19141645 25416803 mrna cleavage,inhibition western blot TarBase
URS0000508C13 MRE11 19141645 25416803 mrna cleavage,inhibition western blot TarBase
URS00000ED600 MRE11 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 MRE11 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 MRE11 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000279B6F MRE11 20371350 22012620 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001919B0 MRE11 20371350 22012620 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000004BACE MRE11 20371350 21572407 22012620 23446348 23592263 23706177 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002394F5 MRE11 20371350 21572407 22012620 23446348 23592263 23706177 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000015A0D9 MRE11 20371350 22012620 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005586D0 MRE11 20371350 22012620 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00006097A6 MRE11 20371350 21572407 22012620 23446348 23592263 23706177 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002367FA MRE11 20371350 21572407 22012620 23446348 23592263 23706177 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00005F1B8C MRE11 20371350 21572407 22012620 23446348 23592263 23706177 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000002103A MRE11 20371350 22012620 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005485E8 MRE11 20371350 22012620 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 MRE11 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A MRE11 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 MRE11 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 MRE11 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C MRE11 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 MRE11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED MRE11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 MRE11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 MRE11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000030F801 MRE11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF MRE11 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B MRE11 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A MRE11 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 MRE11 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 MRE11 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB MRE11 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001C308D MRE11 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000157026 MRE11 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000009262D MRE11 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 MRE11 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 MRE11 22135298 phosphorylation N/A PhosphoSite
ATM MRE11 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SNW1 MRE11 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L MRE11 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DAXX MRE11 24234451 24651726 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CIAO1 MRE11 25348397 N/A physical interaction ComPPI
CEP43 MRE11 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SMARCC1 MRE11 25348397 N/A physical interaction ComPPI
EIF2B2 MRE11 25348397 N/A physical interaction ComPPI
TP53BP1 MRE11 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
LMNA MRE11 25348397 N/A physical interaction ComPPI
CELA2B MRE11 25348397 N/A physical interaction ComPPI
AIM2 MRE11 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
TACC3 MRE11 25348397 N/A physical interaction ComPPI
TXNIP MRE11 25348397 N/A physical interaction ComPPI
ATR MRE11 25348397 N/A physical interaction ComPPI
PRKDC MRE11 25348397 N/A physical interaction ComPPI
JUN MRE11 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EP300 MRE11 14525934 16051665 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DHX9 MRE11 25348397 N/A physical interaction ComPPI
NELFB MRE11 25348397 N/A physical interaction ComPPI
GLI1 MRE11 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PAXIP1 MRE11 25348397 N/A physical interaction ComPPI
UBC MRE11 25348397 N/A physical interaction ComPPI
NTRK1 MRE11 25348397 N/A physical interaction ComPPI
PRMT1 MRE11 25348397 N/A physical interaction ComPPI
CDH1 MRE11 25348397 N/A physical interaction ComPPI
PARP1 MRE11 19629035 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPA1 MRE11 25348397 N/A physical interaction ComPPI
FEN1 MRE11 25348397 N/A physical interaction ComPPI
MSH6 MRE11 25348397 N/A physical interaction ComPPI
ASH2L MRE11 17500065 24234451 25348397 physical association molecular sieving ComPPI,IntAct
HNRNPU MRE11 25348397 N/A physical interaction ComPPI
RAB32 MRE11 25348397 N/A physical interaction ComPPI
XRCC6 MRE11 10508516 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
UHRF2 MRE11 25348397 N/A physical interaction ComPPI
TPR MRE11 25348397 N/A physical interaction ComPPI
NFATC2 MRE11 25348397 N/A physical interaction ComPPI
ANG MRE11 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
MAPK8IP2 MRE11 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FANCD2 MRE11 12447395 14525934 19609304 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,ion exchange chromatography,in vivo ComPPI,HPRD,IntAct
BLM MRE11 24234451 25348397 28506294 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ATM MRE11 10608806 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RPA2 MRE11 25348397 N/A physical interaction ComPPI
RPA3 MRE11 25348397 N/A physical interaction ComPPI
TMPO MRE11 25348397 N/A physical interaction ComPPI
QARS1 MRE11 25348397 N/A physical interaction ComPPI
MDM4 MRE11 25348397 N/A physical interaction ComPPI
USP4 MRE11 25348397 N/A physical interaction ComPPI
RBBP8 MRE11 21052091 24234451 25348397 25558984 26807646 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF8 MRE11 25348397 N/A physical interaction ComPPI
RRM2B MRE11 19015526 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HUWE1 MRE11 25348397 N/A physical interaction ComPPI
SUMO2 MRE11 25348397 N/A physical interaction ComPPI
HNRNPA2B1 MRE11 25348397 N/A physical interaction ComPPI
MDM2 MRE11 25348397 N/A physical interaction ComPPI
SPTA1 MRE11 25348397 N/A physical interaction ComPPI
ODF2 MRE11 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
H3-4 MRE11 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
HTT MRE11 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
SKP2 MRE11 25348397 N/A physical interaction ComPPI
YBX3 MRE11 25348397 N/A physical interaction ComPPI
TRRAP MRE11 25348397 N/A physical interaction ComPPI
HDAC6 MRE11 25348397 N/A physical interaction ComPPI
NEK1 MRE11 14525934 14690447 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBE2A MRE11 25348397 N/A physical interaction ComPPI
SIRT1 MRE11 17612497 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MDC1 MRE11 12607005 18583988 24234451 25348397 29656893 association anti tag coimmunoprecipitation,coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EED MRE11 25348397 N/A physical interaction ComPPI
ATRX MRE11 24234451 24651726 25348397 colocalization,association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
USP11 MRE11 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL7 MRE11 25348397 N/A physical interaction ComPPI
H3C1 MRE11 25348397 N/A physical interaction ComPPI
BARD1 MRE11 25348397 N/A physical interaction ComPPI
BACH1 MRE11 25348397 N/A physical interaction ComPPI
FLII MRE11 25348397 N/A physical interaction ComPPI
LRRFIP1 MRE11 25348397 N/A physical interaction ComPPI
DDX1 MRE11 25348397 N/A physical interaction ComPPI
H2AX MRE11 12419185 14525934 16377563 18583988 19234442 22157895 24234451 25348397 colocalization,association,physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
MRE11 NBN 10426999 11238951 12419185 14525934 17500065 17612497 22078559 24234451 25348397 9705271 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MRE11 RAD50 10888888 14525934 16163361 17500065 19197236 24234451 24651726 25348397 8756642 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,fluorescence microscopy,in vitro,in vivo,inference by socio-affinity scoring ComPPI,HPRD,IntAct
MRE11 DCLRE1C 14525934 15456891 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MRE11 CCNE1 12607005 14525934 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
MRE11 LIG1 14525934 25348397 27898060 8530104 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
MRE11 BRCA1 24234451 25348397 29656893 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MRE11 MLH1 25348397 N/A physical interaction ComPPI
MRE11 MSH2 25348397 N/A physical interaction ComPPI
MRE11 RFC1 25348397 N/A physical interaction ComPPI
MRE11 TERF2IP 25348397 N/A physical interaction ComPPI
MRE11 TERF2 19287395 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRE11 RECQL5 25348397 N/A physical interaction ComPPI
MRE11 NLRP2 25348397 N/A physical interaction ComPPI
MRE11 DCLRE1B 25348397 N/A physical interaction ComPPI
MRE11 KAT5 25348397 N/A physical interaction ComPPI
MRE11 SIRT7 25348397 N/A physical interaction ComPPI
MRE11 TMPO 25348397 N/A physical interaction ComPPI
MRE11 PAN2 25348397 N/A physical interaction ComPPI
MRE11 ABCF1 25348397 N/A physical interaction ComPPI
MRE11 RTCB 25348397 N/A physical interaction ComPPI
MRE11 EIF2B3 25348397 N/A physical interaction ComPPI
MRE11 HNRNPM 25348397 N/A physical interaction ComPPI
MRE11 IGF2BP3 25348397 N/A physical interaction ComPPI
MRE11 MAP7 25348397 N/A physical interaction ComPPI
MRE11 NMT1 25348397 N/A physical interaction ComPPI
MRE11 RFC4 25348397 N/A physical interaction ComPPI
MRE11 RPL26L1 25348397 N/A physical interaction ComPPI
MRE11 RPL27 25348397 N/A physical interaction ComPPI
MRE11 OBSL1 25348397 N/A physical interaction ComPPI
MRE11 FAM219A 25348397 N/A physical interaction ComPPI
MRE11 FBXW11 25348397 N/A physical interaction ComPPI
MRE11 AIDA 25348397 N/A physical interaction ComPPI
MRE11 CHAMP1 25348397 N/A physical interaction ComPPI
MRE11 DRC1 25348397 N/A physical interaction ComPPI
MRE11 GCC2 25348397 N/A physical interaction ComPPI
MRE11 HOOK3 25348397 N/A physical interaction ComPPI
MRE11 SMARCC2 25348397 N/A physical interaction ComPPI
MRE11 OFD1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRE11 AK1 25348397 N/A physical interaction ComPPI
MRE11 TINF2 25348397 N/A physical interaction ComPPI
MRE11 SLX4 25348397 N/A physical interaction ComPPI
MRE11 FOXP1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MRE11 SENP3 25348397 N/A physical interaction ComPPI
MRE11 PCGF1 25348397 N/A physical interaction ComPPI
MRE11 NANOGP8 25348397 N/A physical interaction ComPPI
MRE11 NANOG 25348397 N/A physical interaction ComPPI
MRE11 POU5F1 25348397 N/A physical interaction ComPPI
MRE11 EXD2 24234451 25348397 26807646 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRE11 BMP1 25348397 N/A physical interaction ComPPI
MRE11 RGS20 25348397 N/A physical interaction ComPPI
MRE11 SCG3 25348397 N/A physical interaction ComPPI
MRE11 CFAP161 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MRE11 BRIP1 25348397 N/A physical interaction ComPPI
MRE11 MCM9 25348397 N/A physical interaction ComPPI
MRE11 APEX1 20808282 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
MRE11 RAD17 24234451 24534091 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
ILF2 MRE11 20808282 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
ATF2 MRE11 25348397 N/A physical interaction ComPPI
RTRAF MRE11 25348397 N/A physical interaction ComPPI
MRE11 MRE11 22078559 24234451 N/A cosedimentation in solution,molecular sieving,x-ray crystallography IntAct
MKI67 MRE11 24234451 26949251 association anti tag coimmunoprecipitation IntAct
MRE11 UBA2 23443654 25231868 27898060 N/A N/A OmniPath
MRE11 ATM 10608806 10783165 15758953 15908798 16622404 18854157 21763684 27898060 stimulant N/A OmniPath
ATM MRE11 10608806 10783165 15758953 15845385 18854157 19709933 21763684 26240375 27898060 stimulant N/A OmniPath
RBBP8 MRE11 17965729 21052091 27898060 stimulant N/A OmniPath
PRMT1 MRE11 15741314 27898060 stimulant N/A OmniPath
MRE11 FANCD2 12447395 19609304 27898060 N/A N/A OmniPath
RPA2 MRE11 19586055 27898060 stimulant N/A OmniPath
CSNK2A1 MRE11 15845385 27898060 N/A N/A OmniPath
PARP1 MRE11 18025084 27898060 stimulant N/A OmniPath
MRE11 NBN 10426999 10783165 11238951 12419185 12447395 12607003 12679336 15734743 15758953 17500065 17713585 18458108 19244116 19270065 21884979 22078559 22464731 22939629 26455393 27898060 9705271 stimulant N/A OmniPath
RAD50 MRE11 10219078 10508516 10783165 10888888 11430828 11454871 11470800 11504724 11741545 12607003 14992724 15126391 15165861 15734743 16143598 16163361 16391231 17500065 17713585 18042458 19197236 19270065 21892167 22072981 22705791 22939629 25527408 26344197 26455393 27898060 7625279 7789757 8756642 9705271 9755192 9845372 stimulant N/A OmniPath

Visualization










  Return