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GENE：ACYP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACYP2
FullNmae acylphosphatase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:180
EnsembleID ENSG00000170634
Uniprot P14621

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACYP2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ACYP2 GO:0003998,GO:0005515,GO:0006796,GO:0042802

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ACYP2 hsa:98 path:hsa00620 Pyruvate metabolism - Homo sapiens (human)
ACYP2 hsa:98 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ACYP2 CEBPD 21072181 23180781 physical association anti tag coimmunoprecipitation InnateDB
ACYP2 SULT2B1 23180781 25416956 physical association two hybrid InnateDB
ACYP2 CREBZF 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR ACYP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ACYP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ACYP2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ACYP2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC ACYP2 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ACYP2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 ACYP2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ACYP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
ACYP2 CREBZF 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ACYP2 SULT2B1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ACYP2 SDCBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACYP2 ACYP2 16084386 24234451 N/A classical fluorescence spectroscopy,dynamic light scattering IntAct

Source Target Pmid Interactiontype Methods Database
URS00008BB7EE ACYP2 27087310 direct interaction,inhibition N/A NPInter

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