GENE：AIF1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AIF1 |
| FullNmae | allograft inflammatory factor 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:352 |
| EnsembleID | ENSG00000204472 |
| Uniprot | P55008 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AIF1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| AIF1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AIF1 | GO:0001726,GO:0001774,GO:0001891,GO:0003674,GO:0005509,GO:0005509,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005884,GO:0005884,GO:0005884,GO:0006911,GO:0006954,GO:0006954,GO:0008284,GO:0010468,GO:0016601,GO:0030027,GO:0030041,GO:0030046,GO:0030335,GO:0032587,GO:0032587,GO:0032722,GO:0032755,GO:0034599,GO:0042102,GO:0048471,GO:0048661,GO:0048662,GO:0050921,GO:0051015,GO:0051015,GO:0051017,GO:0051017,GO:0051764,GO:0071346,GO:0071346,GO:0071672,GO:0071673,GO:0071677,GO:0090026,GO:0090271,GO:0097178,GO:0097178,GO:0097178,GO:0097386,GO:1900087,GO:2000406 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA2 | AIF1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | AIF1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | AIF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AIF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | AIF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | AIF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PHB | AIF1 | 24234451 24380853 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| ACTA1 | AIF1 | 12714565 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| AIF1 | LCP1 | 14525934 14756805 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |