GENE:CPT1A
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | CPT1A |
FullNmae | carnitine palmitoyltransferase 1A |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:2328 |
EnsembleID | ENSG00000110090 |
Uniprot | P50416 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
CPT1A | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
CPT1A | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
CPT1A | GO:0001676,GO:0004095,GO:0004095,GO:0004095,GO:0004095,GO:0005739,GO:0005739,GO:0005741,GO:0005741,GO:0005741,GO:0006006,GO:0006631,GO:0006635,GO:0006641,GO:0006853,GO:0009410,GO:0009437,GO:0009437,GO:0010883,GO:0014070,GO:0016020,GO:0030855,GO:0031667,GO:0032000,GO:0042755,GO:0042802,GO:0043279,GO:0045471,GO:0050796,GO:0071398,GO:0097421,GO:1904772,GO:1990698 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
CPT1A | hsa:1374 | path:hsa00071 | Fatty acid degradation - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa01212 | Fatty acid metabolism - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa03320 | PPAR signaling pathway - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa04148 | Efferocytosis - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa04152 | AMPK signaling pathway - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa04714 | Thermogenesis - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa04920 | Adipocytokine signaling pathway - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa04922 | Glucagon signaling pathway - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa04931 | Insulin resistance - Homo sapiens (human) |
CPT1A | hsa:1374 | path:hsa04936 | Alcoholic liver disease - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | CPT1A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | CPT1A | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
YBX1 | CPT1A | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | CPT1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
PPARA | CPT1A | 17150915 | trascriptional regulation,stimulation | inferred by curator | TFlink |
AR | CPT1A | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
CREB1 | CPT1A | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | CPT1A | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00004900F1 | CPT1A | 20124555 | rna interference,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS00004900F1 | CPT1A | 20124555 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS0000338542 | CPT1A | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS00000F4AC3 | CPT1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000018D2BE | CPT1A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000277201 | CPT1A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075AB14 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000016FD1A | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001AFC71 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000021D7C8 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000021D08 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000DDD35 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000298BA3 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002B3783 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000042E1F | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002075FA | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000600E6 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000039E1E1 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000508C13 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041E949 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000027080C | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000070CD2 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000346991 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000078918 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000EE7F0 | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003B59DF | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000E1E9E | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003FA24D | CPT1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075B538 | CPT1A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001FC26E | CPT1A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000160683 | CPT1A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000017DBB8 | CPT1A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000CBE63 | CPT1A | 25416803 27199118 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ERLIN1 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
PCBP1 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
NPDC1 | CPT1A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
KBTBD7 | CPT1A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
NDUFAF4 | CPT1A | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
LYN | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
RHOA | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
RAB7A | CPT1A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TUBG1 | CPT1A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
UBC | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
NTRK1 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
ENO1 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
HSPA5 | CPT1A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
CACYBP | CPT1A | 24234451 25036637 25348397 | physical association | luminescence based mammalian interactome mapping | ComPPI,IntAct |
HNRNPL | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
GABRG2 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
EIF3C | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
PDHA1 | CPT1A | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
HUWE1 | CPT1A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
NR4A1 | CPT1A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
RNF2 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
HDAC6 | CPT1A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CYBA | CPT1A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
BCL2 | CPT1A | 14525934 25348397 27898060 9070836 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
PRKN | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
CLIC1 | CPT1A | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
LPP | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
HDAC11 | CPT1A | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TRIM25 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
ESR2 | CPT1A | 21182203 24234451 25348397 | association | affinity chromatography technology,cosedimentation through density gradient | ComPPI,IntAct |
SNRNP200 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
TOMM40 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | CLN3 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | PCK1 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | CPS1 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | NDUFA2 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | NDUFV1 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | NDUFS1 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | FBXO6 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | LGR4 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | HERC2 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | HERC2P3 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | COQ9 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | NDUFA4 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | TBC1D9 | 25348397 | N/A | physical interaction | ComPPI |
CPT1A | SDHA | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
CPT1A | E2F3 | 22157815 24234451 25348397 | association | pull down | ComPPI,IntAct |
CPT1A | COX6B1 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
ATP6V1C1 | CPT1A | 25348397 | N/A | physical interaction | ComPPI |