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GENE：MTAP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTAP
FullNmae methylthioadenosine phosphorylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7413
EnsembleID ENSG00000099810
Uniprot Q13126

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTAP immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MTAP ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MTAP GO:0004645,GO:0005515,GO:0005654,GO:0005829,GO:0005829,GO:0005829,GO:0006139,GO:0006166,GO:0017061,GO:0019509,GO:0019509,GO:0032259,GO:0033574,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MTAP hsa:4507 path:hsa00270 Cysteine and methionine metabolism - Homo sapiens (human)
MTAP hsa:4507 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 MTAP 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MTAP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 MTAP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MTAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D MTAP 19013014 rna interference,inhibition western blot,northern blot,miRNA interference luciferase reporter assay miRSponge
URS000009262D MTAP 18591254 19013014 25416803 mrna cleavage,inhibition array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 MTAP 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000EED18 MTAP 20371350 21566225 25416803 mrna cleavage,inhibition experimental interaction detection,nucleotide sequence identification TarBase
URS00003E6EFA MTAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004505E4 MTAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 MTAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F MTAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 MTAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 MTAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002DD349 MTAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED MTAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 MTAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 MTAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A MTAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C MTAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED MTAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 MTAP 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MYLIP MTAP 25361965 interaction type N/A PTMCode2
MTAP MYLIP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UROD MTAP 25348397 N/A physical interaction ComPPI
CFL1 MTAP 25348397 N/A physical interaction ComPPI
MCM2 MTAP 25348397 N/A physical interaction ComPPI
CENPH MTAP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CHRAC1 MTAP 25348397 N/A physical interaction ComPPI
JUN MTAP 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CPNE1 MTAP 25348397 N/A physical interaction ComPPI
UBE2D2 MTAP 25348397 N/A physical interaction ComPPI
PDIA3 MTAP 25348397 N/A physical interaction ComPPI
GLRX MTAP 25348397 N/A physical interaction ComPPI
RAB1A MTAP 25348397 N/A physical interaction ComPPI
SUMO3 MTAP 25348397 N/A physical interaction ComPPI
MAP1LC3A MTAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CSE1L MTAP 25348397 N/A physical interaction ComPPI
ASS1 MTAP 25348397 N/A physical interaction ComPPI
PCMT1 MTAP 25348397 N/A physical interaction ComPPI
TRIM25 MTAP 25348397 N/A physical interaction ComPPI
EIF2B1 MTAP 25348397 N/A physical interaction ComPPI
ELAVL1 MTAP 25348397 N/A physical interaction ComPPI
UBE2H MTAP 25348397 N/A physical interaction ComPPI
ARF4 MTAP 25348397 N/A physical interaction ComPPI
TALDO1 MTAP 25348397 N/A physical interaction ComPPI
ATP6V1A MTAP 25348397 N/A physical interaction ComPPI
RBM12 MTAP 25348397 N/A physical interaction ComPPI
DAZAP1 MTAP 25348397 N/A physical interaction ComPPI
MYLIP MTAP 12826659 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
CDC25A MTAP 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FUS MTAP 25348397 N/A physical interaction ComPPI
RELB MTAP 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PNP MTAP 25348397 N/A physical interaction ComPPI
HPRT1 MTAP 25348397 N/A physical interaction ComPPI
PPIL3 MTAP 25348397 N/A physical interaction ComPPI
HINT1 MTAP 25348397 N/A physical interaction ComPPI
CEP170 MTAP 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUMO4 MTAP 25348397 N/A physical interaction ComPPI
GMPS MTAP 25348397 N/A physical interaction ComPPI
GOT1 MTAP 25348397 N/A physical interaction ComPPI
LYPLA2 MTAP 25348397 N/A physical interaction ComPPI
SNX3 MTAP 25348397 N/A physical interaction ComPPI
SCLT1 MTAP 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CNN2 MTAP 25348397 N/A physical interaction ComPPI
MTAP FOLH1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTAP LYRM1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTAP ANXA6 25348397 N/A physical interaction ComPPI
MTAP CUTA 25348397 N/A physical interaction ComPPI
MTAP MTPN 25348397 N/A physical interaction ComPPI
MTAP NAXD 25348397 N/A physical interaction ComPPI
MTAP CYRIB 25348397 N/A physical interaction ComPPI
MTAP GNPDA2 25348397 N/A physical interaction ComPPI
MTAP SNX12 25348397 N/A physical interaction ComPPI
MTAP TAGLN2 25348397 N/A physical interaction ComPPI
MTAP TAGLN3 25348397 N/A physical interaction ComPPI
MTAP UFM1 25348397 N/A physical interaction ComPPI
MTAP EMC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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