Gene Information gene info

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GENE：RDX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RDX
FullNmae radixin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9944
EnsembleID ENSG00000137710
Uniprot P35241

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RDX mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RDX ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RDX GO:0003723,GO:0003779,GO:0003779,GO:0005515,GO:0005615,GO:0005886,GO:0005886,GO:0005886,GO:0005902,GO:0005902,GO:0005912,GO:0005925,GO:0005925,GO:0008360,GO:0008360,GO:0008361,GO:0010628,GO:0010737,GO:0016324,GO:0030027,GO:0030175,GO:0030175,GO:0030315,GO:0030335,GO:0030496,GO:0030864,GO:0032154,GO:0032231,GO:0032487,GO:0034111,GO:0034260,GO:0036120,GO:0043087,GO:0045176,GO:0045177,GO:0045296,GO:0045732,GO:0045792,GO:0050839,GO:0051016,GO:0051018,GO:0051117,GO:0051286,GO:0061028,GO:0061951,GO:0070062,GO:0071944,GO:0072659,GO:0097067,GO:1900027,GO:1900087,GO:1902115,GO:1902115,GO:1902966,GO:1902966,GO:1903392,GO:2000643,GO:2000643

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RDX hsa:5962 path:hsa04530 Tight junction - Homo sapiens (human)
RDX hsa:5962 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
RDX hsa:5962 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
RDX hsa:5962 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR RDX 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 RDX 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 RDX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB5 RDX 21132541 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000001EB3 RDX 19524507 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000001EB3 RDX 19524507 22089331 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000081E1F RDX 22179828 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000324096 RDX 18668040 21572407 23446348 25416803 26701625 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS00001597DC RDX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 RDX 21572407 23446348 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS000052E1A6 RDX 21572407 23446348 24933454 25416803 26701625 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00001A6D0C RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C85C7 RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003D8730 RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000243FF1 RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A07C1 RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000031E12 RDX 21572407 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000085F64 RDX 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 RDX 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000D5FFC RDX 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 RDX 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 RDX 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKCQ RDX 22135298 phosphorylation N/A PhosphoSite
LRRK2 RDX 22135298 phosphorylation N/A PhosphoSite
ROCK1 RDX 22135298 phosphorylation N/A PhosphoSite
GRK2 RDX 22135298 phosphorylation N/A PhosphoSite
MAP3K8 RDX 22135298 phosphorylation N/A PhosphoSite
MAP4K4 RDX 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
ARHGDIG RDX 25348397 N/A physical interaction ComPPI
GTF2A1 RDX 25348397 N/A physical interaction ComPPI
VCP RDX 25348397 N/A physical interaction ComPPI
VPS11 RDX 25348397 N/A physical interaction ComPPI
CALM1 RDX 25348397 N/A physical interaction ComPPI
ROCK1 RDX 14525934 25348397 9456324 N/A experimental interaction detection,in vitro ComPPI,HPRD
ERBB2 RDX 25348397 N/A physical interaction ComPPI
LYN RDX 25348397 N/A physical interaction ComPPI
GDI2 RDX 25348397 N/A physical interaction ComPPI
SLC9A3R1 RDX 12499563 14525934 25348397 9430655 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CPNE1 RDX 12522145 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
CPNE2 RDX 12522145 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
CPNE4 RDX 12522145 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
MCF2 RDX 24234451 25348397 9681826 physical association coimmunoprecipitation,pull down ComPPI,IntAct
ARHGDIA RDX 14525934 24234451 25348397 9287351 9681826 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SLC9A3R2 RDX 12499563 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PGD RDX 25348397 N/A physical interaction ComPPI
NTRK1 RDX 25348397 N/A physical interaction ComPPI
ENO1 RDX 25348397 N/A physical interaction ComPPI
CDH1 RDX 25348397 N/A physical interaction ComPPI
SNX2 RDX 25348397 N/A physical interaction ComPPI
CALR RDX 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
L1CAM RDX 12070130 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
STIP1 RDX 25348397 N/A physical interaction ComPPI
P4HB RDX 25348397 N/A physical interaction ComPPI
ITGB2 RDX 17321526 24234451 25348397 physical association pull down,enzyme linked immunosorbent assay,in vitro ComPPI,IntAct
CFTR RDX 25348397 N/A physical interaction ComPPI
GNA13 RDX 10816569 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
AKR1B1 RDX 25348397 N/A physical interaction ComPPI
RDX ABCC2 12068294 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
RDX EZR 14525934 23414517 24234451 25348397 26496610 29568061 9501018 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid fragment pooling approach,in vivo,proximity-dependent biotin identification ComPPI,HPRD,IntAct
RDX TSC1 10806479 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
RDX ICAM2 11375520 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
RDX DRD3 25348397 N/A physical interaction ComPPI
RDX PHLPP2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RDX ELAVL1 25348397 N/A physical interaction ComPPI
RDX BRCA1 25348397 N/A physical interaction ComPPI
RDX TRAPPC10 25348397 N/A physical interaction ComPPI
RDX NCL 25348397 N/A physical interaction ComPPI
RDX PRDX6 25348397 N/A physical interaction ComPPI
RDX ESR1 21182205 24234451 25348397 association cosedimentation through density gradient,physical interaction ComPPI,IntAct
RDX MAPK10 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RDX ANP32E 25348397 N/A physical interaction ComPPI
RDX CTTN 25348397 N/A physical interaction ComPPI
RDX GSPT1 25348397 N/A physical interaction ComPPI
RDX GSPT2 25348397 N/A physical interaction ComPPI
RDX ATG7 25348397 N/A physical interaction ComPPI
RDX LPP 25348397 N/A physical interaction ComPPI
RDX NSUN2 25348397 N/A physical interaction ComPPI
RDX RNASEH2B 25348397 N/A physical interaction ComPPI
RDX RNF2 25348397 N/A physical interaction ComPPI
RDX ACAA2 25348397 N/A physical interaction ComPPI
RDX BCAP31 25348397 N/A physical interaction ComPPI
RDX BRWD1 25348397 N/A physical interaction ComPPI
RDX CLIC1 25348397 N/A physical interaction ComPPI
RDX FABP5P3 25348397 N/A physical interaction ComPPI
RDX FABP5 25348397 N/A physical interaction ComPPI
RDX HSD17B10 25348397 N/A physical interaction ComPPI
RDX HSPA4 25348397 N/A physical interaction ComPPI
RDX HSPE1 25348397 N/A physical interaction ComPPI
RDX HSPH1 25348397 N/A physical interaction ComPPI
RDX ISYNA1 25348397 N/A physical interaction ComPPI
RDX LCP1 25348397 N/A physical interaction ComPPI
RDX NOTCH2 25348397 N/A physical interaction ComPPI
RDX PLS1 25348397 N/A physical interaction ComPPI
RDX PLS3 25348397 N/A physical interaction ComPPI
RDX PPA1 25348397 N/A physical interaction ComPPI
RDX PSMB5 25348397 N/A physical interaction ComPPI
RDX RCN1 25348397 N/A physical interaction ComPPI
RDX EEF2 25348397 N/A physical interaction ComPPI
RDX IMPA2 25348397 N/A physical interaction ComPPI
RDX TRMT6 25348397 N/A physical interaction ComPPI
RDX TAGLN2 25348397 N/A physical interaction ComPPI
RDX TKT 25348397 N/A physical interaction ComPPI
RDX TKTL2 25348397 N/A physical interaction ComPPI
RDX TXNRD2 25348397 N/A physical interaction ComPPI
RDX UCHL3 25348397 N/A physical interaction ComPPI
RDX UFD1 25348397 N/A physical interaction ComPPI
RDX MRPL12 25348397 N/A physical interaction ComPPI
RDX SLC25A10 25348397 N/A physical interaction ComPPI
RDX MISP 25348397 N/A physical interaction ComPPI
RDX TRIM25 25348397 N/A physical interaction ComPPI
RDX PLEK 19722192 24234451 25348397 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
RDX GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RDX C1QTNF9 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
RDX PSME3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
RDX BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
RDX PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPF RDX 25348397 N/A physical interaction ComPPI
CALU RDX 25348397 N/A physical interaction ComPPI
ATP6V1C1 RDX 25348397 N/A physical interaction ComPPI
CI RDX 25348397 N/A anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,physical interaction ComPPI
RDX CUL3 16740475 17880263 27898060 N/A N/A OmniPath
ROCK1 RDX 20068231 27898060 9456324 stimulant N/A OmniPath
GNA13 RDX 10816569 27898060 stimulant N/A OmniPath
PRKCQ RDX 11146558 14504278 15676024 17447891 19255442 19395553 20801872 21864676 21979959 25531779 25799996 27898060 stimulant N/A OmniPath
CDK1 RDX 27898060 9456324 N/A N/A OmniPath

Visualization










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