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GENE：TNFRSF14

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNFRSF14
FullNmae TNF receptor superfamily member 14
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11912
EnsembleID ENSG00000157873
Uniprot Q92956

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNFRSF14 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TNFRSF14 GO:0001618,GO:0002250,GO:0002720,GO:0005031,GO:0005515,GO:0005886,GO:0005886,GO:0006955,GO:0007166,GO:0009897,GO:0019955,GO:0031295,GO:0031625,GO:0033209,GO:0045087,GO:0046642,GO:0046718,GO:0050731,GO:0050829,GO:0050830,GO:1905675,GO:2000406

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNFRSF14 hsa:8764 path:hsa03266 Virion - Herpesvirus - Homo sapiens (human)
TNFRSF14 hsa:8764 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
TNFRSF14 hsa:8764 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)
TNFRSF14 hsa:8764 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TNFSF14 TNFRSF14 11164894 23180781 physical association solid phase assay InnateDB
TNFRSF14 LTA 11164894 23180781 physical association solid phase assay InnateDB
RAD21 TNFRSF14 22145905 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
GRB2 TNFRSF14 20005715 interaction type N/A PSP
TRAF1 TNFRSF14 20005715 interaction type N/A PSP
TRAF2 TNFRSF14 20005715 interaction type N/A PSP
TRAF3 TNFRSF14 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
ETS1 TNFRSF14 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 TNFRSF14 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TNFRSF14 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
BTLA TNFRSF14 25361965 interaction type N/A PTMCode2
TNFRSF14 BTLA 25361965 interaction type N/A PTMCode2
TNFRSF14 LTA 25361965 interaction type N/A PTMCode2
LTA TNFRSF14 25361965 interaction type N/A PTMCode2
GATA5 TNFRSF14 25361965 interaction type N/A PTMCode2
TNFRSF14 GATA5 25361965 interaction type N/A PTMCode2
TNFSF13 TNFRSF14 25361965 interaction type N/A PTMCode2
TNFRSF14 TNFSF13 25361965 interaction type N/A PTMCode2
TRAF3 TNFRSF14 25361965 interaction type N/A PTMCode2
TNFRSF14 TRAF3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DYNLL1 TNFRSF14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
VIM TNFRSF14 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HSPBP1 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NRIP1 TNFRSF14 14525934 25348397 9774688 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
DPM1 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VCP TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ZBTB48 TNFRSF14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAD21 TNFRSF14 25348397 N/A physical interaction ComPPI
MRM3 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3E TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GDI2 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GRB2 TNFRSF14 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
DHX9 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HDAC3 TNFRSF14 11463856 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HDAC4 TNFRSF14 11463856 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PSMA3 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PDIA6 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRMT1 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
P4HB TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF3 TNFRSF14 14525934 24234451 25348397 9162022 physical association experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
BTLA TNFRSF14 14525934 15568026 21982860 24234451 25348397 physical association experimental interaction detection,protein array,physical interaction,in vivo ComPPI,HPRD,IntAct
ST13 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPL TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TRAF1 TNFRSF14 14525934 24234451 25348397 9162022 physical association experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
TRAF2 TNFRSF14 14525934 17353931 19332782 24234451 25348397 9153189 9162022 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
TRAF5 TNFRSF14 14525934 24234451 25348397 9153189 9162022 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
DRAP1 TNFRSF14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBQLN4 TNFRSF14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3I TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CEP126 TNFRSF14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HTRA2 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SSR4 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SSB TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDC37 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPE1 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PER2 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFSF14 TNFRSF14 10318773 11390428 14525934 24234451 25348397 26977880 9462508 physical association experimental interaction detection,fluorescence-activated cell sorting,yeast display,physical interaction,enzyme linked immunosorbent assay,in vivo ComPPI,HPRD,IntAct
MBTPS1 TNFRSF14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ESR1 TNFRSF14 12093804 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNFRSF14 LTA 14525934 24234451 25348397 9153189 9462508 physical association experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct
TNFRSF14 UGGT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFRSF14 GCN1 25348397 N/A physical interaction ComPPI
TNFRSF14 SEC11B 25348397 N/A physical interaction ComPPI
TNFRSF14 SEC11A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFRSF14 CHD3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TNFRSF14 TNFSF13 10706119 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TNFRSF14 ITFG1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFRSF14 WDR73 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFRSF14 SERPINA4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFRSF14 A2M 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFRSF14 DGKD 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFRSF14 NDUFS2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFRSF14 IMPA2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFRSF14 APP 25348397 N/A physical interaction ComPPI
TNFRSF14 CD160 21982860 24234451 25348397 physical association protein array,physical interaction ComPPI,IntAct
TNFRSF14 A1BG 25348397 N/A affinity chromatography technology,physical interaction ComPPI
TNFRSF14 AIFM1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 CCDC59 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 MICOS13 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 NCLN 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 GET4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 RPL36 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 SRPRB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 SLC25A22 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 SPCS2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 SLC25A10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 GCLM 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 TARDBP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 DCD 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 PFDN2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 RUVBL2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 DNAJA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 PCED1A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 LHPP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 CNIH4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 MAIP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB1 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MIF TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HPRT1 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSPH TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFRSF14 TNFRSF14 12093804 14525934 N/A experimental interaction detection HPRD
TNFSF14 TNFRSF14 10318773 10894944 11164894 11390428 27898060 9462508 stimulant N/A OmniPath

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