Gene Information gene info

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GENE：MPG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MPG
FullNmae N-methylpurine DNA glycosylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7211
EnsembleID ENSG00000103152
Uniprot P29372

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MPG ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MPG GO:0003684,GO:0003905,GO:0005515,GO:0005654,GO:0005654,GO:0005829,GO:0006284,GO:0006307,GO:0008725,GO:0019104,GO:0042645,GO:0043916,GO:0045007,GO:0052821,GO:0052822

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MPG hsa:4350 path:hsa03410 Base excision repair - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP MPG 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MPG 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MPG 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
EGR1 MPG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MPG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR MPG 24913494 trascriptional regulation,stimulation inferred by curator TFlink
SP1 MPG 10563836 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 MPG 10563836 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A MPG 10563836 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MPG N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 MPG 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000DDD35 MPG 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
NUDT21 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ATP5PO MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
FXR2 MPG 25348397 N/A physical interaction ComPPI
NPM1 MPG 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTM3 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SET MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD7 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
H2BC4 MPG 25348397 N/A physical interaction ComPPI
CRK MPG 25348397 N/A physical interaction ComPPI
HSD17B14 MPG 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RACGAP1 MPG 25348397 N/A physical interaction ComPPI
RPL10 MPG 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUN MPG 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EP300 MPG 14525934 14761960 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FLG MPG 25348397 N/A physical interaction ComPPI
THRB MPG 14525934 14761960 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RAB7A MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PRNP MPG 18482256 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,protein array,physical interaction,fluorescence microscopy ComPPI,IntAct
XRCC1 MPG 18971944 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RPA1 MPG 25348397 N/A physical interaction ComPPI
PRDX1 MPG 25348397 N/A physical interaction ComPPI
PSMA1 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CAPZA1 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CACYBP MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UHRF2 MPG 25348397 N/A physical interaction ComPPI
PKM MPG 25348397 N/A physical interaction ComPPI
RANBP1 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPA2 MPG 25348397 N/A physical interaction ComPPI
RPA3 MPG 25348397 N/A physical interaction ComPPI
CLASP2 MPG 25348397 N/A physical interaction ComPPI
MORF4L1 MPG 25348397 N/A physical interaction ComPPI
RAD23A MPG 10854423 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SRSF1 MPG 25348397 N/A physical interaction ComPPI
OBSCN MPG 25348397 N/A physical interaction ComPPI
GNL3 MPG 25348397 N/A physical interaction ComPPI
MDC1 MPG 25348397 N/A physical interaction ComPPI
FBLN1 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD23B MPG 10854423 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TFIP11 MPG 25348397 N/A physical interaction ComPPI
HSPE1 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CSTF1 MPG 25348397 N/A physical interaction ComPPI
NCBP1 MPG 25348397 N/A physical interaction ComPPI
ELP2 MPG 25348397 N/A physical interaction ComPPI
ELP1 MPG 25348397 N/A physical interaction ComPPI
ESR1 MPG 14525934 14761960 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RFC4 MPG 25348397 N/A physical interaction ComPPI
PAFAH1B2 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HECW2 MPG 25348397 N/A physical interaction ComPPI
TERF2IP MPG 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
EXOSC9 MPG 25348397 N/A physical interaction ComPPI
KHSRP MPG 25348397 N/A physical interaction ComPPI
MACF1 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UHRF1 MPG 23537643 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PPP1R10 MPG 25348397 N/A physical interaction ComPPI
PIN4 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PRPF38B MPG 25348397 N/A physical interaction ComPPI
RRP1B MPG 25348397 N/A physical interaction ComPPI
MPG LRRC59 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MPG GOT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MPG HDGF 25348397 N/A physical interaction ComPPI
MPG PRNP 25348397 N/A physical interaction ComPPI
MPG APP 25348397 N/A physical interaction ComPPI
MPG SERPINA12 25348397 N/A physical interaction ComPPI
MPG DHX33 25348397 N/A physical interaction ComPPI
MPG CDSN 25348397 N/A physical interaction ComPPI
MPG GSN 25348397 N/A physical interaction ComPPI
MPG LHCGR 25348397 N/A physical interaction ComPPI
MPG NOC2L 25348397 N/A physical interaction ComPPI
MPG SART1 25348397 N/A physical interaction ComPPI
MPG RPRD2 25348397 N/A physical interaction ComPPI
MPG POLR1F 25348397 N/A physical interaction ComPPI
MPG KDM2A 25348397 N/A physical interaction ComPPI
MPG GNL2 25348397 N/A physical interaction ComPPI
MPG LARP4 25348397 N/A physical interaction ComPPI
MPG CST6 25348397 N/A physical interaction ComPPI
MPG KPRP 25348397 N/A physical interaction ComPPI
MPG ELP3 25348397 N/A physical interaction ComPPI
MPG KBTBD4 25348397 N/A physical interaction ComPPI
MPG EIF2A 25348397 N/A physical interaction ComPPI
MPG KIFC1 25348397 N/A physical interaction ComPPI
MPG H2BC11 25348397 N/A physical interaction ComPPI
MPG OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MPG RPL35A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG PSMC2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG MOB1A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG RPS29 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG ETFA 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG ACAT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG SOD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MIF MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RRP7A MPG 25348397 N/A physical interaction ComPPI
MPG RXRA 14525934 14761960 N/A experimental interaction detection HPRD
MPG MPG 17353931 24234451 physical association anti bait coimmunoprecipitation IntAct
GPR182 MPG 24234451 28298427 physical association ubiquitin reconstruction IntAct
HSPD1 MPG 24234451 30021884 physical association cross-linking study IntAct
MPG ESR1 14761960 17129768 27898060 inhibition N/A OmniPath
MPG MBD1 17129768 27898060 stimulant N/A OmniPath

Visualization










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