GENE:TPD52
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TPD52 |
| FullNmae | tumor protein D52 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:12005 |
| EnsembleID | ENSG00000076554 |
| Uniprot | P55327 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TPD52 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TPD52 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TPD52 | GO:0005509,GO:0005515,GO:0005737,GO:0005737,GO:0005783,GO:0009653,GO:0030183,GO:0030183,GO:0042803,GO:0046903,GO:0048471 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TPD52 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | TPD52 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | TPD52 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | TPD52 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | TPD52 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000338542 | TPD52 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00000EED18 | TPD52 | 20371350 21566225 25416803 | mrna cleavage,inhibition | experimental interaction detection,nucleotide sequence identification | TarBase |
| URS000017EA6A | TPD52 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000041CB9C | TPD52 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000184017 | TPD52 | 21572407 24768995 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
| URS00002971AB | TPD52 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D15B | TPD52 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037E170 | TPD52 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000004CA3 | TPD52 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CF1AD | TPD52 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F24A9 | TPD52 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EE123 | TPD52 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002233F4 | TPD52 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000E601 | TPD52 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | TPD52 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ECFE5 | TPD52 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000052EA98 | TPD52 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023BE29 | TPD52 | 25416803 27785063 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BAG3 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| H2BC4 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| AR | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| PRKACA | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| DUT | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAZ | TPD52 | 15161933 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| PDIA6 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| PHB | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| SOCS2 | TPD52 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PTGES3 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPU | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| CACYBP | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| MAPK6 | TPD52 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| PDLIM5 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAQ | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| PDCD4 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52L1 | TPD52 | 14525934 24234451 25348397 9484778 | physical association | two hybrid,experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,IntAct |
| ARPC1B | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| DYNC1H1 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| SRPK2 | TPD52 | 23602568 24234451 25348397 | phosphorylation reaction | physical interaction,protein kinase assay | ComPPI,IntAct |
| CLIC4 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| STUB1 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| SENP2 | TPD52 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| SOD1 | TPD52 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| TGOLN2 | TPD52 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PAIP1 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| UCHL3 | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| IKBKE | TPD52 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| TPD52 | TPD52L3 | 14525934 16631610 24234451 25348397 | physical association | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD,IntAct |
| TPD52 | SAR1A | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | AARS1 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | MRPS2 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | ENO2 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | EZR | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | H2BC11 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | THOC2 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | MRPS11 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | MEAF6 | 25348397 | N/A | physical interaction | ComPPI |
| TPD52 | CTNNA3 | 25348397 | N/A | physical interaction | ComPPI |
| CALU | TPD52 | 25348397 | N/A | physical interaction | ComPPI |
| ANXA6 | TPD52 | 14525934 15576473 27898060 | N/A | experimental interaction detection | HPRD,OmniPath |
| CAMK2D | TPD52 | 18832449 20032513 20946871 23868405 24637012 27898060 | N/A | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00008C0549 | TPD52 | 27087310 | direct interaction,inhibition | N/A | NPInter |
