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GENE：RHOBTB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RHOBTB1
FullNmae Rho related BTB domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18738
EnsembleID ENSG00000072422
Uniprot O94844

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RHOBTB1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RHOBTB1 GO:0003924,GO:0005515,GO:0005525,GO:0005886,GO:0006897,GO:0007015,GO:0007163,GO:0010008,GO:0019901,GO:0032488

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RHOBTB1 hsa:9886 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR RHOBTB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 RHOBTB1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 RHOBTB1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 RHOBTB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RHOBTB1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RHOBTB1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RHOBTB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 RHOBTB1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000001EB3 RHOBTB1 23258531 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 RHOBTB1 25348397 N/A physical interaction ComPPI
HSP90AB1 RHOBTB1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
COPS5 RHOBTB1 25348397 N/A physical interaction ComPPI
CUL3 RHOBTB1 18835386 21145461 23040068 25348397 26100637 27898060 N/A physical interaction ComPPI,OmniPath
HSP90AA1 RHOBTB1 25348397 N/A physical interaction ComPPI
PIGR RHOBTB1 25348397 N/A physical interaction ComPPI
COPS6 RHOBTB1 25348397 N/A physical interaction ComPPI
COPS7A RHOBTB1 25348397 N/A physical interaction ComPPI
UBE2M RHOBTB1 25348397 N/A physical interaction ComPPI
CST5 RHOBTB1 25348397 N/A physical interaction ComPPI
JCHAIN RHOBTB1 25348397 N/A physical interaction ComPPI
APBB3 RHOBTB1 25348397 N/A physical interaction ComPPI

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