GENE:GAS7
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GAS7 |
| FullNmae | growth arrest specific 7 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4169 |
| EnsembleID | ENSG00000007237 |
| Uniprot | O60861 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GAS7 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GAS7 | GO:0005515,GO:0005737,GO:0005884,GO:0005886,GO:0030041,GO:0048812,GO:0051015 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | GAS7 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | GAS7 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | GAS7 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP53 | GAS7 | 18922183 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| FOXP3 | GAS7 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | GAS7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000D5659 | GAS7 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CC709 | GAS7 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004C5774 | GAS7 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB0E | GAS7 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FF522 | GAS7 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000195F5B | GAS7 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D8730 | GAS7 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000306C70 | GAS7 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018CD09 | GAS7 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| WAS | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| PACSIN1 | GAS7 | 20936779 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| KHDRBS1 | GAS7 | 16055720 24234451 25348397 26766589 | association,physical association | pull down,physical interaction | ComPPI,IntAct |
| SFPQ | GAS7 | 16055720 24234451 25348397 26766589 | association,physical association | pull down,physical interaction | ComPPI,IntAct |
| GAPDH | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| PRMT1 | GAS7 | 24234451 25348397 26766589 | association | pull down | ComPPI,IntAct |
| DIAPH1 | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| FMNL1 | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| APBB1IP | GAS7 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPU | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| RPLP0 | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| ABI1 | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| SF3A1 | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| NCKIPSD | GAS7 | 25348397 | N/A | physical interaction | ComPPI |
| SF1 | GAS7 | 25348397 | N/A | physical interaction | ComPPI |
| CYFIP1 | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| CYFIP2 | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| BECN1 | GAS7 | 22081109 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| NCKAP1 | GAS7 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| PACSIN2 | GAS7 | 25348397 | N/A | physical interaction | ComPPI |
| ACTA1 | GAS7 | 11795944 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| NTAQ1 | GAS7 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CBFB | GAS7 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| GAS7 | CREB3L2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| GAS7 | WASF2 | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| GAS7 | NCKAP1L | 16055720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| GAS7 | MYBPC2 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| GAS7 | WASF1 | 22606326 27898060 | N/A | N/A | OmniPath |
