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GENE：ADAMTS12

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ADAMTS12
FullNmae ADAM metallopeptidase with thrombospondin type 1 motif 12
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14605
EnsembleID ENSG00000151388
Uniprot P58397

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ADAMTS12 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ADAMTS12 GO:0002062,GO:0004222,GO:0004222,GO:0005515,GO:0005576,GO:0006508,GO:0007160,GO:0016477,GO:0030167,GO:0030198,GO:0030199,GO:0031012,GO:0032331,GO:0043931,GO:0046872,GO:0050727,GO:0051603,GO:0051603,GO:0071347,GO:0071356,GO:0071773,GO:1901509,GO:1902203,GO:1902548,GO:2001113

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ADAMTS12 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ADAMTS12 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 ADAMTS12 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA ADAMTS12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ADAMTS12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ADAMTS12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ADAMTS12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ADAMTS12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ADAMTS12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ADAMTS12 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 ADAMTS12 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 ADAMTS12 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
CALM1 ADAMTS12 25348397 N/A physical interaction ComPPI
SNRK ADAMTS12 25348397 N/A physical interaction ComPPI
PPM1A ADAMTS12 25348397 N/A physical interaction ComPPI
USF2 ADAMTS12 25348397 N/A physical interaction ComPPI
SP3 ADAMTS12 25348397 N/A physical interaction ComPPI
USF1 ADAMTS12 25348397 N/A physical interaction ComPPI
A2M ADAMTS12 18485748 24234451 25348397 protein cleavage protease assay ComPPI,IntAct
UBR1 ADAMTS12 25348397 N/A physical interaction ComPPI
MYL6 ADAMTS12 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

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