GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
HEATR3 |
FullNmae |
HEAT repeat containing 3 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:26087 |
EnsembleID |
ENSG00000155393 |
Uniprot |
Q7Z4Q2 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
HEATR3 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
HEATR3 |
GO:0006606,GO:0006606,GO:0042273,GO:0042273,GO:0043249,GO:0051082 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
HEATR3 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
GATA2 |
HEATR3 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00000AA464 |
HEATR3 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
URS00004E008F |
HEATR3 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000078918 |
HEATR3 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000209F04 |
HEATR3 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003D4175 |
HEATR3 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
TRAF6 |
HEATR3 |
17353931
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
KEAP1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
NCK1 |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
JUN |
HEATR3 |
24234451
25348397
25609649
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
PTPN1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
MYC |
HEATR3 |
17353931
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
ST13 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
EPHA1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
LNPEP |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
EGFR |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
CD70 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
CA9 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
VIPR2 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
HTR2C |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PTPRN |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
ELAVL1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
HNRNPD |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
CHRM4 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
DSP |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
CHRM3 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PNKD |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
SURF2 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
PTP4A3 |
HEATR3 |
17353931
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
NCAPH |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
ST6GAL1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
HEATR3 |
LMAN2 |
25348397
|
N/A |
physical interaction |
ComPPI |
HEATR3 |
CD83 |
25348397
|
N/A |
physical interaction |
ComPPI |
NONO |
HEATR3 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
Visualization