GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
HEATR3 |
| FullNmae |
HEAT repeat containing 3 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:26087 |
| EnsembleID |
ENSG00000155393 |
| Uniprot |
Q7Z4Q2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| HEATR3 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| HEATR3 |
GO:0006606,GO:0006606,GO:0042273,GO:0042273,GO:0043249,GO:0051082 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
HEATR3 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
HEATR3 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
HEATR3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00000AA464 |
HEATR3 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00004E008F |
HEATR3 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000078918 |
HEATR3 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000209F04 |
HEATR3 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00003D4175 |
HEATR3 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| TRAF6 |
HEATR3 |
17353931
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
| KEAP1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| NCK1 |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| JUN |
HEATR3 |
24234451
25348397
25609649
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
| PTPN1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MYC |
HEATR3 |
17353931
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
| ST13 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| EPHA1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| LNPEP |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| EGFR |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CD70 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CA9 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| VIPR2 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HTR2C |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PTPRN |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ELAVL1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HNRNPD |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| CHRM4 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| DSP |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| CHRM3 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PNKD |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| SURF2 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PTP4A3 |
HEATR3 |
17353931
24234451
25348397
|
physical association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
| NCAPH |
HEATR3 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| ST6GAL1 |
HEATR3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HEATR3 |
LMAN2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HEATR3 |
CD83 |
25348397
|
N/A |
physical interaction |
ComPPI |
| NONO |
HEATR3 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
Visualization