GENE:F13A1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | F13A1 |
| FullNmae | coagulation factor XIII A chain |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3531 |
| EnsembleID | ENSG00000124491 |
| Uniprot | P00488 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| F13A1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| F13A1 | GO:0003810,GO:0003810,GO:0005515,GO:0005576,GO:0005615,GO:0007596,GO:0018149,GO:0018149,GO:0031093,GO:0046872,GO:0062023,GO:0072378,GO:0072378,GO:0072562,GO:1990234 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| F13A1 | hsa:2162 | path:hsa04610 | Complement and coagulation cascades - Homo sapiens (human) |
| F13A1 | hsa:2162 | path:hsa05171 | Coronavirus disease - COVID-19 - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | F13A1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | F13A1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | F13A1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CEBPA | F13A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | F13A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | F13A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | F13A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | F13A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | F13A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | F13A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | F13A1 | 10037697 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA1 | F13A1 | 10037697 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NFIC | F13A1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| F13A1 | FGA | 25361965 | interaction type | N/A | PTMCode2 |
| FGA | F13A1 | 25361965 | interaction type | N/A | PTMCode2 |
| F13A1 | F2 | 25361965 | interaction type | N/A | PTMCode2 |
| F2 | F13A1 | 25361965 | interaction type | N/A | PTMCode2 |
| F13A1 | SERPINF2 | 25361965 | interaction type | N/A | PTMCode2 |
| SERPINF2 | F13A1 | 25361965 | interaction type | N/A | PTMCode2 |
| F13A1 | F13B | 25361965 | interaction type | N/A | PTMCode2 |
| F13B | F13A1 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NUDT21 | F13A1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| CDKN1A | F13A1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| TK1 | F13A1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| DDIT4L | F13A1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| F2 | F13A1 | 14525934 25348397 9546612 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| SERPINF2 | F13A1 | 10958788 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HSPB1 | F13A1 | 23397142 24234451 25348397 27898060 7915282 | physical association | coimmunoprecipitation,experimental interaction detection,physical interaction,proximity ligation assay | ComPPI,IntAct,OmniPath |
| SH3GL2 | F13A1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| UFD1 | F13A1 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PLEK | F13A1 | 19722192 24234451 25348397 | association | pull down | ComPPI,IntAct |
| F13A1 | F13B | 14525934 2491853 25348397 8905624 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| F13A1 | FGA | 10956659 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| F13A1 | FGG | 10828988 14525934 25348397 27898060 8905624 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| F13A1 | FN1 | 14525934 25348397 8905624 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| F13A1 | PTK2 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| F13A1 | ANXA7 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| F13A1 | F13A1 | 14525934 2184890 2365049 7660355 7913750 7920263 9515726 9988734 | N/A | experimental interaction detection | HPRD |
| F13A1 | ITGB1 | 10816592 27898060 | N/A | N/A | OmniPath |
| IL7R | F13A1 | 20167604 27898060 | N/A | N/A | OmniPath |
| F13A1 | ITGA4 | 10816592 27898060 | N/A | N/A | OmniPath |
| F13A1 | ITGA9 | 10816592 27898060 | N/A | N/A | OmniPath |
