GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
TRAM1 |
FullNmae |
translocation associated membrane protein 1 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:20568 |
EnsembleID |
ENSG00000067167 |
Uniprot |
Q15629 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
TRAM1 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
TRAM1 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
TRAM1 |
GO:0005515,GO:0005783,GO:0005789,GO:0005789,GO:0006613,GO:0006616,GO:0006986,GO:0016020,GO:0038023,GO:0045048,GO:0045048 |
KEGG Annotation:
GeneSymbol |
GeneID |
Pathway |
Pathway Name |
TRAM1 |
hsa:23471 |
path:hsa04141 |
Protein processing in endoplasmic reticulum - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
TRAM1 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
ETS1 |
TRAM1 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TP53 |
TRAM1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000338542 |
TRAM1 |
N/A
|
rna interference,inhibition |
experimental interaction detection |
miRSponge |
URS0000338542 |
TRAM1 |
18668040
22473208
25416803
|
mrna cleavage,inhibition |
experimental interaction detection,clip |
TarBase |
URS000003ABC4 |
TRAM1 |
20371350
25416803
|
mrna cleavage,inhibition |
nucleotide sequence identification |
TarBase |
URS00000DDD35 |
TRAM1 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
URS0000279B6F |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000015A0D9 |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000039607D |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000453664 |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000E7139 |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001925C1 |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000020CEC2 |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000008DA94 |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000003E1A9 |
TRAM1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000040EE1D |
TRAM1 |
22473208
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000041CB9C |
TRAM1 |
22473208
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000171CD1 |
TRAM1 |
22473208
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
TRAF6 |
TRAM1 |
12721283
14525934
25348397
|
N/A |
experimental interaction detection,in vivo |
ComPPI,HPRD |
PKN2 |
TRAM1 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBC |
TRAM1 |
25348397
|
N/A |
physical interaction |
ComPPI |
SEC61B |
TRAM1 |
14525934
25348397
27898060
9512475
|
N/A |
experimental interaction detection,in vivo |
ComPPI,HPRD,OmniPath |
TIRAP |
TRAM1 |
25348397
|
N/A |
in vivo |
ComPPI |
BCAP31 |
TRAM1 |
18555783
24234451
25348397
|
colocalization,physical association |
anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,ubiquitin reconstruction,physical interaction,fluorescence microscopy |
ComPPI,IntAct |
CREB3 |
TRAM1 |
21516116
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
HLA-A |
TRAM1 |
25348397
|
N/A |
physical interaction |
ComPPI |
ELAVL1 |
TRAM1 |
25348397
|
N/A |
physical interaction |
ComPPI |
DERL1 |
TRAM1 |
25348397
|
N/A |
physical interaction |
ComPPI |
ESR1 |
TRAM1 |
25348397
|
N/A |
physical interaction |
ComPPI |
ESR2 |
TRAM1 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRAM1 |
TICAM1 |
12721283
14525934
25348397
|
N/A |
experimental interaction detection,in vivo |
ComPPI,HPRD |
TRAM1 |
HM13 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRAM1 |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
TRAM1 |
FAF2 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRAM1 |
DRD2 |
24234451
28298427
|
physical association |
ubiquitin reconstruction |
IntAct |
Visualization