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GENE：DDX39B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DDX39B
FullNmae DExD-box helicase 39B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13917
EnsembleID ENSG00000198563
Uniprot Q13838

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DDX39B parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DDX39B ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DDX39B GO:0000245,GO:0000346,GO:0000398,GO:0000398,GO:0003723,GO:0003723,GO:0003724,GO:0003724,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005681,GO:0005687,GO:0005688,GO:0005737,GO:0006405,GO:0006406,GO:0006406,GO:0006406,GO:0008186,GO:0008380,GO:0010501,GO:0016607,GO:0016887,GO:0017070,GO:0030621,GO:0032786,GO:0042802,GO:0043008,GO:0046784,GO:2000002

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DDX39B hsa:7919 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)
DDX39B hsa:7919 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)
DDX39B hsa:7919 path:hsa03040 Spliceosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUZ12 DDX39B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
EED DDX39B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 DDX39B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 DDX39B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
FOXP3 DDX39B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DDX39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DDX39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DDX39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DDX39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 DDX39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR DDX39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 DDX39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 DDX39B 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000058863C DDX39B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000009265 DDX39B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E728C DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000195F5B DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006DA05 DDX39B 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000018E72A DDX39B 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F9738 DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000148B91 DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000419B5A DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000547F6A DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B7450 DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000043D2C1 DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004BC299 DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000078918 DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000024CEE0 DDX39B 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001E0AEA DDX39B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000029EBD DDX39B 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000F7766 DDX39B 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIAS2 DDX39B 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
TFAP4 DDX39B 25348397 N/A physical interaction ComPPI
SNW1 DDX39B 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MAGOHB DDX39B 25348397 N/A physical interaction ComPPI
CDC5L DDX39B 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SNRPA DDX39B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPN1 DDX39B 25348397 N/A physical interaction ComPPI
RPS7 DDX39B 25348397 N/A physical interaction ComPPI
EMD DDX39B 25348397 N/A physical interaction ComPPI
TP53BP1 DDX39B 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
YWHAG DDX39B 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ZC3H10 DDX39B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BMI1 DDX39B 25348397 N/A physical interaction ComPPI
NR5A1 DDX39B 25348397 N/A physical interaction ComPPI
SMAD4 DDX39B 25348397 N/A physical interaction ComPPI
KEAP1 DDX39B 25348397 N/A physical interaction ComPPI
RBM8A DDX39B 23084401 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GRB2 DDX39B 12577067 24234451 25348397 association pull down ComPPI,IntAct
TDG DDX39B 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
RBM39 DDX39B 14525934 14667819 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
U2AF2 DDX39B 25348397 N/A physical interaction ComPPI
DLD DDX39B 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 DDX39B 25348397 N/A physical interaction ComPPI
CDH1 DDX39B 25348397 N/A physical interaction ComPPI
SREK1 DDX39B 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PABPC4 DDX39B 25348397 N/A physical interaction ComPPI
ZFP36 DDX39B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THOC5 DDX39B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PABPC1 DDX39B 25348397 N/A physical interaction ComPPI
NDRG1 DDX39B 25348397 N/A physical interaction ComPPI
ANG DDX39B 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
SDCBP DDX39B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBBP4 DDX39B 25348397 N/A physical interaction ComPPI
THOC1 DDX39B 11979277 23299939 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDK2 DDX39B 25348397 N/A physical interaction ComPPI
EHHADH DDX39B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZHX1 DDX39B 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
RNF2 DDX39B 25348397 N/A physical interaction ComPPI
HIPK2 DDX39B 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
WWOX DDX39B 25348397 N/A physical interaction ComPPI
MDC1 DDX39B 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
UQCRC2 DDX39B 25348397 N/A physical interaction ComPPI
VCAM1 DDX39B 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 DDX39B 25348397 N/A physical interaction ComPPI
EED DDX39B 25348397 N/A physical interaction ComPPI
DNM1L DDX39B 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SSR3 DDX39B 25348397 N/A physical interaction ComPPI
CUL7 DDX39B 25348397 N/A physical interaction ComPPI
HDAC5 DDX39B 25348397 N/A physical interaction ComPPI
BCLAF1 DDX39B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF4 DDX39B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BARD1 DDX39B 25348397 N/A physical interaction ComPPI
SEM1 DDX39B 24234451 24811749 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BACH1 DDX39B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LSM4 DDX39B 25348397 N/A physical interaction ComPPI
TRIM25 DDX39B 25348397 N/A physical interaction ComPPI
NCBP1 DDX39B 25348397 N/A physical interaction ComPPI
NCBP2 DDX39B 25348397 N/A physical interaction ComPPI
ELAVL1 DDX39B 25348397 N/A physical interaction ComPPI
TUBB4A DDX39B 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SRPK2 DDX39B 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RAE1 DDX39B 25348397 N/A physical interaction ComPPI
STRN4 DDX39B 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EIF4A2 DDX39B 25348397 N/A physical interaction ComPPI
DDX39A DDX39B 14525934 14667819 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
EIF4E DDX39B 19262567 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SOD1 DDX39B 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EXOSC9 DDX39B 14667819 24234451 25348397 physical association two hybrid ComPPI,IntAct
MOB4 DDX39B 25348397 N/A physical interaction ComPPI
MAGOH DDX39B 23084401 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ALYREF DDX39B 11979277 14525934 14667819 15047853 15998806 17190602 21799930 22939629 23222130 23299939 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct,OmniPath
HNRNPLL DDX39B 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
LNX1 DDX39B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATF2 DDX39B 22304920 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TARDBP DDX39B 25348397 N/A physical interaction ComPPI
DHX38 DDX39B 25348397 N/A physical interaction ComPPI
EIF4A3 DDX39B 23084401 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
SUZ12 DDX39B 25348397 N/A physical interaction ComPPI
MED19 DDX39B 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
THOC7 DDX39B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SARNP DDX39B 14525934 14667819 15338056 24234451 25348397 physical association two hybrid,experimental interaction detection,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
HSPD1 DDX39B 25348397 N/A physical interaction ComPPI
MYO1C DDX39B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FYTTD1 DDX39B 25348397 N/A physical interaction ComPPI
CYLD DDX39B 25348397 N/A physical interaction ComPPI
NTAQ1 DDX39B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPS15A DDX39B 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
DDX39B TUBB3 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
DDX39B FANCA 25348397 N/A physical interaction ComPPI
DDX39B DNM2 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DDX39B MC1R 25348397 N/A physical interaction ComPPI
DDX39B THOC2 11979277 24234451 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
DDX39B THOC3 25348397 N/A physical interaction ComPPI
DDX39B THOC6 25348397 N/A physical interaction ComPPI
DDX39B PYM1 25348397 N/A physical interaction ComPPI
DDX39B TXNL1 25348397 N/A physical interaction ComPPI
DDX39B WDR74 25348397 N/A physical interaction ComPPI
DDX39B VPS33B 25348397 N/A physical interaction ComPPI
DDX39B UBE3A 25348397 N/A physical interaction ComPPI
DDX39B FN1 25348397 N/A physical interaction ComPPI
DDX39B IL7R 25348397 N/A physical interaction ComPPI
DDX39B MYG1 25348397 N/A physical interaction ComPPI
DDX39B SEM1 25348397 N/A physical interaction ComPPI
DDX39B STAU1 25348397 N/A physical interaction ComPPI
DDX39B OBSL1 25348397 N/A physical interaction ComPPI
DDX39B LUZP4 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDX39B DDOST 25348397 N/A physical interaction ComPPI
DDX39B AHSA1 25348397 N/A physical interaction ComPPI
DDX39B RPN2 25348397 N/A physical interaction ComPPI
DDX39B TECR 25348397 N/A physical interaction ComPPI
DDX39B ETFA 25348397 N/A physical interaction ComPPI
DDX39B RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX39B NCBP3 24234451 25348397 26382858 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
DDX39B CHTOP 14667819 23299939 24234451 25348397 30021884 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,cross-linking study,pull down ComPPI,IntAct
DDX39B ACAA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACADM DDX39B 25348397 N/A physical interaction ComPPI
GSR DDX39B 25348397 N/A physical interaction ComPPI
DDX41 DDX39B 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
HSCB DDX39B 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
DDX39B DDX39B 14525934 14667819 15296731 24234451 physical association two hybrid,experimental interaction detection,two hybrid array,two hybrid prey pooling approach,two hybrid HPRD,IntAct
METTL14 DDX39B 24234451 29507755 association anti tag coimmunoprecipitation IntAct
DDX39B API5 24234451 30021884 physical association cross-linking study IntAct
PLK1 DDX39B 21637952 27898060 N/A N/A OmniPath

Visualization










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