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GENE：EFNA5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EFNA5
FullNmae ephrin A5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3225
EnsembleID ENSG00000184349
Uniprot P52803

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EFNA5 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EFNA5 GO:0001934,GO:0005168,GO:0005169,GO:0005170,GO:0005515,GO:0005604,GO:0005886,GO:0005886,GO:0005886,GO:0005901,GO:0005912,GO:0007399,GO:0007411,GO:0009897,GO:0022407,GO:0022407,GO:0022604,GO:0030297,GO:0031290,GO:0032956,GO:0032956,GO:0043087,GO:0043087,GO:0045499,GO:0046875,GO:0046875,GO:0048013,GO:0048013,GO:0048668,GO:0048672,GO:0050731,GO:0050919,GO:0051893,GO:0051965,GO:0061178,GO:0070507,GO:0071372,GO:0098982,GO:0099560,GO:1900025,GO:1904322

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EFNA5 hsa:1946 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
EFNA5 hsa:1946 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
EFNA5 hsa:1946 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
EFNA5 hsa:1946 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
EFNA5 hsa:1946 path:hsa04360 Axon guidance - Homo sapiens (human)
EFNA5 hsa:1946 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LYL1 EFNA5 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB
EFNA5 EPHA5 10531456 18988627 23331499 9267020 stimulation N/A SignaLink,SignaLink
EFNA5 EPHA6 23331499 9576626 stimulation N/A SignaLink,SignaLink
EFNA5 EPHA7 10366629 18988627 23331499 9576626 stimulation N/A SignaLink,SignaLink
EFNA5 EPHA4 18988627 23331499 8755474 9576626 stimulation N/A SignaLink,SignaLink
EFNA5 EPHA3 18988627 21071413 23331499 9195962 9245480 9576626 9751130 stimulation N/A SignaLink,SignaLink
EFNA5 EPHA8 11416136 23331499 9576626 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR EFNA5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F6 EFNA5 12909625 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 EFNA5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 EFNA5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C EFNA5 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 EFNA5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 EFNA5 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 EFNA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 EFNA5 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000260A3A EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000003BF62 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000048B5E9 EFNA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B EFNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 EFNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A EFNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 EFNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 EFNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 EFNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 EFNA5 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EFNA5 EPHA3 25361965 interaction type N/A PTMCode2
EPHA3 EFNA5 25361965 interaction type N/A PTMCode2
EFNA5 EPHA2 25361965 interaction type N/A PTMCode2
EPHA2 EFNA5 25361965 interaction type N/A PTMCode2
EFNA5 EPHA7 25361965 interaction type N/A PTMCode2
EPHA7 EFNA5 25361965 interaction type N/A PTMCode2
EFNA5 EPHB2 25361965 interaction type N/A PTMCode2
EPHB2 EFNA5 25361965 interaction type N/A PTMCode2
EFNA5 EPHB1 25361965 interaction type N/A PTMCode2
EPHB1 EFNA5 25361965 interaction type N/A PTMCode2
EPHA8 EFNA5 25361965 interaction type N/A PTMCode2
EFNA5 EPHA8 25361965 interaction type N/A PTMCode2
EPHA4 EFNA5 25361965 interaction type N/A PTMCode2
EFNA5 EPHA4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MED21 EFNA5 25348397 N/A physical interaction ComPPI
KASH5 EFNA5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRC EFNA5 25348397 N/A physical interaction ComPPI
EPHB2 EFNA5 14525934 15107857 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
EPHA2 EFNA5 14525934 20228801 20505120 24234451 25348397 9245480 physical association experimental interaction detection,light scattering,molecular sieving,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EPHA8 EFNA5 11416136 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EFNA5 EPHA3 14525934 25348397 9195962 9245480 9751130 N/A experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD
EFNA5 EPHA5 10531456 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EFNA5 EPHB1 14525934 25348397 9245480 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EFNA5 EPHA7 10366629 14525934 22036564 24234451 25348397 N/A experimental interaction detection,physical interaction,in vitro,comigration in sds page ComPPI,HPRD,IntAct
EFNA5 EPHA4 14525934 19836338 23812375 24234451 25348397 8755474 N/A experimental interaction detection,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,surface plasmon resonance array ComPPI,HPRD,IntAct
EFNA5 GRIP1 25348397 N/A physical interaction ComPPI
EFNA5 GJB7 25348397 N/A physical interaction ComPPI
EFNA5 CYP2S1 25348397 N/A physical interaction ComPPI
EFNA5 HNRNPL 25348397 N/A physical interaction ComPPI
EFNA5 ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
EFNA5 GJB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 ACKR2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 HERPUD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 MS4A3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 TM4SF18 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 GPR161 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 AQP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 CD53 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 RHCG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 YIPF6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 TRHR 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 SLC10A2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 SLC13A4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 GPR152 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 SGPL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 TSPO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 CYB561 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 SSMEM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 CLDN5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 HIBADH 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 GPR151 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 GPR42 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 BEST2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA5 FFAR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BIRC2 EFNA5 24234451 30561431 association virotrap IntAct
EFNA5 EPHA2 20228801 20505120 27898060 9245480 9330863 stimulant N/A OmniPath
EFNA5 EPHA4 19836338 23812375 27898060 8755474 9330863 9576626 stimulant N/A OmniPath
EFNA5 EPHB6 15107857 27898060 N/A N/A OmniPath
EPHA3 EFNA5 15114347 27898060 9195962 9245480 9751130 N/A N/A OmniPath
EFNA5 EPHA3 27898060 9195962 9245480 9330863 9751130 stimulant N/A OmniPath
EFNA5 EPHA5 10531456 27898060 9330863 stimulant N/A OmniPath
EFNA5 EPHA8 11416136 27898060 9330863 stimulant N/A OmniPath

Visualization










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