GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
FBXL4 |
FullNmae |
F-box and leucine rich repeat protein 4 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:13601 |
EnsembleID |
ENSG00000112234 |
Uniprot |
Q9UKA2 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
FBXL4 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
FBXL4 |
GO:0000151,GO:0000422,GO:0005515,GO:0005758,GO:0005829,GO:0006511,GO:0016607,GO:0019005,GO:0031146 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
FBXL4 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
FOXP3 |
FBXL4 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
SMARCA4 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
GATA2 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
PRDM14 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
SPI1 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TRIM28 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
FBXL4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00000AF45F |
FBXL4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000058BB84 |
FBXL4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075D1FC |
FBXL4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005CCD18 |
FBXL4 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
LGALS3 |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
CALML3 |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
SKP1 |
FBXL4 |
10531037
14525934
24234451
25348397
27705803
|
association |
experimental interaction detection,physical interaction,in vitro,tandem affinity purification |
ComPPI,HPRD,IntAct |
PROCR |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM29 |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
XPO1 |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
DUSP14 |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
PKP1 |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
PKP3 |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
FBXL4 |
KDM4A |
25348397
|
N/A |
physical interaction |
ComPPI |
FBXL4 |
CLGN |
25348397
|
N/A |
physical interaction |
ComPPI |
FBXL4 |
EXOSC2 |
24234451
25348397
26496610
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
FBXL4 |
CNPY2 |
25348397
|
N/A |
physical interaction |
ComPPI |
FBXL4 |
SUN2 |
25348397
|
N/A |
physical interaction |
ComPPI |
FBXL4 |
SERPINB5 |
25348397
|
N/A |
physical interaction |
ComPPI |
FBXL4 |
BBS7 |
25348397
|
N/A |
physical interaction |
ComPPI |
PADI3 |
FBXL4 |
25348397
|
N/A |
physical interaction |
ComPPI |
Visualization