Gene Information gene info

GENE:ICA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ICA1
FullNmae islet cell autoantigen 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5343
EnsembleID ENSG00000003147
Uniprot Q05084

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ICA1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ICA1 GO:0000139,GO:0005515,GO:0005737,GO:0005794,GO:0005829,GO:0005829,GO:0006836,GO:0019904,GO:0030667,GO:0030672,GO:0043231,GO:0051049,GO:0140090

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ICA1 hsa:3382 path:hsa04940 Type I diabetes mellitus - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 ICA1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ICA1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ICA1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ICA1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ICA1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ICA1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ICA1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ICA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
EXOC5 ICA1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STK16 ICA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT33B ICA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CNTF ICA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PICK1 ICA1 25348397 N/A physical interaction ComPPI
MYC ICA1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RAB2A ICA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MORF4L1 ICA1 25348397 N/A physical interaction ComPPI
ING5 ICA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MBD3 ICA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

Visualization