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GENE：LPIN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LPIN2
FullNmae lipin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14450
EnsembleID ENSG00000101577
Uniprot Q92539

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LPIN2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LPIN2 GO:0003713,GO:0003713,GO:0005634,GO:0005789,GO:0005789,GO:0005829,GO:0006629,GO:0008195,GO:0008195,GO:0008195,GO:0009062,GO:0019432,GO:0019432,GO:0032869,GO:0045944,GO:0045944

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LPIN2 hsa:9663 path:hsa00561 Glycerolipid metabolism - Homo sapiens (human)
LPIN2 hsa:9663 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
LPIN2 hsa:9663 path:hsa01100 Metabolic pathways - Homo sapiens (human)
LPIN2 hsa:9663 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
LPIN2 hsa:9663 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LPIN2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LPIN2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 LPIN2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 LPIN2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 LPIN2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 LPIN2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 LPIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LPIN2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00004E008F LPIN2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PPP1CA LPIN2 22321011 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FBXW11 LPIN2 25348397 N/A physical interaction ComPPI

Visualization










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