GENE：MYO9B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MYO9B |
| FullNmae | myosin IXB |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:7609 |
| EnsembleID | ENSG00000099331 |
| Uniprot | Q13459 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MYO9B | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MYO9B | GO:0000146,GO:0000146,GO:0001726,GO:0003779,GO:0005096,GO:0005096,GO:0005515,GO:0005516,GO:0005524,GO:0005524,GO:0005737,GO:0005829,GO:0005829,GO:0005884,GO:0005884,GO:0005938,GO:0007266,GO:0015629,GO:0016020,GO:0016459,GO:0016887,GO:0030027,GO:0030048,GO:0030048,GO:0030048,GO:0031267,GO:0035023,GO:0035385,GO:0043531,GO:0046872,GO:0048471,GO:0048495,GO:0051015,GO:0051056,GO:0072673 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MYO9B | hsa:4650 | path:hsa04814 | Motor proteins - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | MYO9B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | MYO9B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | MYO9B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | MYO9B | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | MYO9B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | MYO9B | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00005651EE | MYO9B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000DDD35 | MYO9B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000000B1C9 | MYO9B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000008931A | MYO9B | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D5391 | MYO9B | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000321A1A | MYO9B | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000367985 | MYO9B | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CALM1 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| MCM2 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| MOAP1 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| FOXG1 | MYO9B | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| SKAP1 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| PKN2 | MYO9B | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| NTRK1 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| CDH5 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| MYC | MYO9B | 17314511 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| GRK5 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| LRRC41 | MYO9B | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| HLA-DPA1 | MYO9B | 25348397 | N/A | physical interaction | ComPPI |
| MYO9B | CALM2 | 14525934 9490638 | N/A | experimental interaction detection | HPRD |
| MYO9B | ARFGEF1 | 14525934 15644318 27898060 | N/A | experimental interaction detection,two hybrid | HPRD,OmniPath |
| MYO9B | ACTA1 | 14525934 27898060 9490638 | N/A | experimental interaction detection | HPRD,OmniPath |
| RCN1 | MYO9B | 24234451 30021884 | physical association | cross-linking study | IntAct |
| HMGN3 | MYO9B | 24234451 30021884 | physical association | cross-linking study | IntAct |
| H1-5 | MYO9B | 24234451 30021884 | physical association | cross-linking study | IntAct |
| H1-2 | MYO9B | 24234451 30021884 | physical association | cross-linking study | IntAct |