GENE：VGF
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | VGF |
| FullNmae | VGF nerve growth factor inducible |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:12684 |
| EnsembleID | ENSG00000128564 |
| Uniprot | O15240 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| VGF | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| VGF | GO:0001541,GO:0002021,GO:0003674,GO:0005179,GO:0005184,GO:0005615,GO:0005615,GO:0005788,GO:0005794,GO:0006091,GO:0007165,GO:0008083,GO:0009409,GO:0019953,GO:0030073,GO:0030133,GO:0031410,GO:0032868,GO:0033500,GO:0042593,GO:0042742,GO:0043025,GO:0043231,GO:0048167,GO:0048168,GO:0051591,GO:0098978,GO:0099538 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| VGF | hsa:7425 | path:hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MYC | VGF | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| YBX1 | VGF | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| E2F4 | VGF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | VGF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | VGF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | VGF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NPAS3 | VGF | 21709683 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| REST | VGF | 19118055 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CREB1 | VGF | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00005FDE70 | VGF | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000419B5A | VGF | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004929F1 | VGF | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002373FD | VGF | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000004DB7E | VGF | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NTRK1 | VGF | 25348397 | N/A | physical interaction | ComPPI |
| RNF2 | VGF | 25348397 | N/A | physical interaction | ComPPI |
| PRKN | VGF | 25348397 | N/A | physical interaction | ComPPI |
| SUZ12 | VGF | 25348397 | N/A | physical interaction | ComPPI |
| LRRK1 | VGF | 24234451 24947832 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| LRRK2 | VGF | 24234451 24947832 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| PPT1 | VGF | 25348397 | N/A | physical interaction | ComPPI |