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GENE：ARHGEF10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARHGEF10
FullNmae Rho guanine nucleotide exchange factor 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14103
EnsembleID ENSG00000104728
Uniprot O15013

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARHGEF10 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARHGEF10 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARHGEF10 GO:0005085,GO:0005085,GO:0005515,GO:0005813,GO:0005813,GO:0005829,GO:0005829,GO:0019894,GO:0022011,GO:0030036,GO:0051056,GO:0051298,GO:0051496,GO:0051496,GO:0090307,GO:0090307,GO:0090630

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ARHGEF10 LYL1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ARHGEF10 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 ARHGEF10 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ARHGEF10 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ARHGEF10 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 ARHGEF10 19074876 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 ARHGEF10 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CD2AP ARHGEF10 25348397 N/A physical interaction ComPPI
KIF3B ARHGEF10 19635168 24234451 25348397 27898060 association,physical association anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy ComPPI,IntAct,OmniPath
SART3 ARHGEF10 25348397 N/A physical interaction ComPPI
PTRH2 ARHGEF10 25348397 N/A physical interaction ComPPI
COPG1 ARHGEF10 25348397 N/A physical interaction ComPPI
TGOLN2 ARHGEF10 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 ARHGEF10 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SETD2 ARHGEF10 25348397 N/A physical interaction ComPPI
RNF31 ARHGEF10 25348397 N/A physical interaction ComPPI
CCDC88A ARHGEF10 25348397 N/A physical interaction ComPPI
SSBP2 ARHGEF10 25348397 N/A physical interaction ComPPI
CBWD3 ARHGEF10 25348397 N/A physical interaction ComPPI
WDR48 ARHGEF10 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARHGEF10 PSME4 25348397 N/A physical interaction ComPPI
ARHGEF10 SPSB2 25348397 N/A physical interaction ComPPI
ARHGEF10 DNAJB5 25348397 N/A physical interaction ComPPI
ARHGEF10 RSPRY1 25348397 N/A physical interaction ComPPI
HMGA1 ARHGEF10 24234451 30021884 physical association cross-linking study IntAct

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