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GENE：PAFAH1B2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PAFAH1B2
FullNmae platelet activating factor acetylhydrolase 1b catalytic subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8575
EnsembleID ENSG00000168092
Uniprot P68402

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PAFAH1B2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAFAH1B2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAFAH1B2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PAFAH1B2 GO:0001650,GO:0003847,GO:0005515,GO:0005576,GO:0005730,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0006629,GO:0007283,GO:0008247,GO:0016042,GO:0016239,GO:0034774,GO:0042803,GO:0044877,GO:0046982,GO:0047179,GO:0070062,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PAFAH1B2 hsa:5049 path:hsa00565 Ether lipid metabolism - Homo sapiens (human)
PAFAH1B2 hsa:5049 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SNTA1 PAFAH1B2 15123239 23180781 physical association peptide array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PAFAH1B2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PAFAH1B2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PAFAH1B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PAFAH1B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PAFAH1B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PAFAH1B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PAFAH1B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PAFAH1B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PAFAH1B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PAFAH1B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 PAFAH1B2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00003D5391 PAFAH1B2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF PAFAH1B2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD PAFAH1B2 20371350 23446348 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 PAFAH1B2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD PAFAH1B2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC PAFAH1B2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 PAFAH1B2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 PAFAH1B2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037E170 PAFAH1B2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 PAFAH1B2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075BEA7 PAFAH1B2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000022AAA PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 PAFAH1B2 20371350 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001EB9FC PAFAH1B2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 PAFAH1B2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 PAFAH1B2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 PAFAH1B2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045E0EC PAFAH1B2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 PAFAH1B2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E PAFAH1B2 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6EFA PAFAH1B2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B PAFAH1B2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF PAFAH1B2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D PAFAH1B2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 PAFAH1B2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 PAFAH1B2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000EBD4B PAFAH1B2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002AAD6B PAFAH1B2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BCD9C PAFAH1B2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002D2333 PAFAH1B2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 PAFAH1B2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E PAFAH1B2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A PAFAH1B2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D PAFAH1B2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF PAFAH1B2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 PAFAH1B2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000482389 PAFAH1B2 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TPD52L2 PAFAH1B2 25348397 N/A physical interaction ComPPI
BAG3 PAFAH1B2 25348397 N/A physical interaction ComPPI
LDHB PAFAH1B2 25348397 N/A physical interaction ComPPI
TRAF6 PAFAH1B2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
YWHAG PAFAH1B2 25348397 N/A physical interaction ComPPI
TUFM PAFAH1B2 25348397 N/A physical interaction ComPPI
CRK PAFAH1B2 25348397 N/A two hybrid,physical interaction ComPPI
ASF1A PAFAH1B2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SLA PAFAH1B2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RHOA PAFAH1B2 25348397 N/A physical interaction ComPPI
RAP1GDS1 PAFAH1B2 25348397 N/A physical interaction ComPPI
YWHAB PAFAH1B2 25348397 N/A physical interaction ComPPI
ARFIP1 PAFAH1B2 25348397 N/A physical interaction ComPPI
PDIA4 PAFAH1B2 25348397 N/A physical interaction ComPPI
TRIP6 PAFAH1B2 25348397 N/A physical interaction ComPPI
EIF6 PAFAH1B2 25348397 N/A physical interaction ComPPI
PAFAH1B1 PAFAH1B2 10727864 14525934 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,physical interaction,in vitro,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
RPLP0 PAFAH1B2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HNRNPA2B1 PAFAH1B2 25348397 N/A physical interaction ComPPI
NAE1 PAFAH1B2 25348397 N/A physical interaction ComPPI
CDK2 PAFAH1B2 25348397 N/A physical interaction ComPPI
YWHAE PAFAH1B2 25348397 N/A physical interaction ComPPI
PINX1 PAFAH1B2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
OGT PAFAH1B2 25348397 N/A physical interaction ComPPI
MSN PAFAH1B2 25348397 N/A physical interaction ComPPI
PRKN PAFAH1B2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACIN1 PAFAH1B2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PPP5C PAFAH1B2 25348397 N/A physical interaction ComPPI
REXO1 PAFAH1B2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAFAH1B2 ZFP36L1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAFAH1B2 SNUPN 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAFAH1B2 PPP1R12C 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAFAH1B2 TIMM50 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAFAH1B2 CCT3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAFAH1B2 RPLP0P6 25348397 N/A physical interaction ComPPI
PAFAH1B2 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PAFAH1B2 HECW2 25348397 N/A physical interaction ComPPI
PAFAH1B2 GINS3 25348397 N/A physical interaction ComPPI
PAFAH1B2 ABHD14A 25348397 N/A physical interaction ComPPI
PAFAH1B2 BZW2 25348397 N/A physical interaction ComPPI
PAFAH1B2 GSS 25348397 N/A physical interaction ComPPI
PAFAH1B2 NAPRT 25348397 N/A physical interaction ComPPI
PAFAH1B2 PLPBP 25348397 N/A physical interaction ComPPI
PAFAH1B2 TATDN1 25348397 N/A physical interaction ComPPI
PAFAH1B2 FAM98B 25348397 N/A physical interaction ComPPI
PAFAH1B2 EIF4H 25348397 N/A physical interaction ComPPI
PAFAH1B2 IDE 25348397 N/A physical interaction ComPPI
PAFAH1B2 PRRC1 25348397 N/A physical interaction ComPPI
PAFAH1B2 PSMG2 25348397 N/A physical interaction ComPPI
PAFAH1B2 PSMG1 25348397 N/A physical interaction ComPPI
PAFAH1B2 RTCB 25348397 N/A physical interaction ComPPI
PAFAH1B2 SHMT2 25348397 N/A physical interaction ComPPI
PAFAH1B2 VARS1 25348397 N/A physical interaction ComPPI
PAFAH1B2 WDR4 25348397 N/A physical interaction ComPPI
PAFAH1B2 STAT3 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PAFAH1B2 NDEL1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B2 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAFAH1B2 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAFAH1B2 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAFAH1B2 NME2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAFAH1B2 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAFAH1B2 CLVS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAFAH1B3 PAFAH1B2 11522926 14525934 16189514 22863883 24234451 25348397 27898060 physical association experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct,OmniPath
RTRAF PAFAH1B2 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00008BF0D4 PAFAH1B2 27087310 direct interaction,inhibition N/A NPInter

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