GENE：SLC7A8
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SLC7A8 |
| FullNmae | solute carrier family 7 member 8 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11066 |
| EnsembleID | ENSG00000092068 |
| Uniprot | Q9UHI5 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SLC7A8 | lysosomal_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| SLC7A8 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| SLC7A8 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SLC7A8 | GO:0003333,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0006865,GO:0006865,GO:0009925,GO:0015101,GO:0015171,GO:0015171,GO:0015171,GO:0015175,GO:0015175,GO:0015175,GO:0015175,GO:0015179,GO:0015180,GO:0015187,GO:0015190,GO:0015190,GO:0015297,GO:0015349,GO:0015349,GO:0015695,GO:0015804,GO:0015804,GO:0015804,GO:0015816,GO:0015820,GO:0015827,GO:0015829,GO:0016323,GO:0016324,GO:0019534,GO:0031528,GO:0035524,GO:0042605,GO:0046982,GO:0070327,GO:0070327,GO:0089718,GO:0098713,GO:0098713,GO:0150104,GO:1901998,GO:1903801,GO:1903801,GO:1904273 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SLC7A8 | hsa:23428 | path:hsa04974 | Protein digestion and absorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | SLC7A8 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | SLC7A8 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | SLC7A8 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | SLC7A8 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | SLC7A8 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | SLC7A8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SYNJ2BP | SLC7A8 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| DERL1 | SLC7A8 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| COMT | SLC7A8 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SIGLEC5 | SLC7A8 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SLC7A8 | NDUFA3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |