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GENE：TAX1BP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TAX1BP1
FullNmae Tax1 binding protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11575
EnsembleID ENSG00000106052
Uniprot Q86VP1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TAX1BP1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TAX1BP1 GO:0000407,GO:0005515,GO:0005739,GO:0005776,GO:0005829,GO:0006914,GO:0006915,GO:0019900,GO:0031410,GO:0032088,GO:0043066,GO:0045087,GO:0046872,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TAX1BP1 hsa:8887 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
TAX1BP1 hsa:8887 path:hsa04140 Autophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TAX1BP1 RIPK1 17703191 18239685 18246070 19131965 23010170 23180781 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
TAX1BP1 TRAF6 10920205 17703191 18239685 18246070 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
TAX1BP1 STARD13 14697242 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
TNFAIP3 TAX1BP1 18239685 23180781 physical association anti tag coimmunoprecipitation InnateDB
TAX1BP1 TNFAIP3 18239685 18246070 23180781 physical association anti tag coimmunoprecipitation InnateDB
TAX1BP1 ITCH 18246070 23180781 physical association anti tag coimmunoprecipitation InnateDB
TAX1BP1 CALCOCO2 17635994 23180781 physical association anti tag coimmunoprecipitation InnateDB
TAX1BP1 UBC 19285159 23180781 physical association protein array InnateDB
TAX1BP1 TAX1BP1 10435631 26467481 bind,up-regulates activity N/A Signor

Source Target Pmid Interactiontype Methods Database
AR TAX1BP1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 TAX1BP1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TAX1BP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 TAX1BP1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TAX1BP1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 TAX1BP1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TAX1BP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB TAX1BP1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 TAX1BP1 20371350 22473208 23592263 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000039A052 TAX1BP1 25416803 25595906 mrna cleavage,inhibition western blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002075FA TAX1BP1 20371350 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F TAX1BP1 20371350 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 TAX1BP1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 TAX1BP1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 TAX1BP1 20371350 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 TAX1BP1 20371350 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 TAX1BP1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE TAX1BP1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 TAX1BP1 20371350 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 TAX1BP1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA TAX1BP1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TNFAIP3 TAX1BP1 25361965 interaction type N/A PTMCode2
TAX1BP1 TNFAIP3 25361965 interaction type N/A PTMCode2
RALBP1 TAX1BP1 25361965 interaction type N/A PTMCode2
TAX1BP1 RALBP1 25361965 interaction type N/A PTMCode2
RNF11 TAX1BP1 25361965 interaction type N/A PTMCode2
TAX1BP1 RNF11 25361965 interaction type N/A PTMCode2
TRAF6 TAX1BP1 25361965 interaction type N/A PTMCode2
TAX1BP1 TRAF6 25361965 interaction type N/A PTMCode2
TIFA TAX1BP1 25361965 interaction type N/A PTMCode2
TAX1BP1 TIFA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TCL1A TAX1BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM90A1 TAX1BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CBX8 TAX1BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DAXX TAX1BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RALBP1 TAX1BP1 17703191 18239685 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GLB1 TAX1BP1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
UBASH3A TAX1BP1 25348397 N/A two hybrid ComPPI
TRAPPC6A TAX1BP1 25348397 N/A two hybrid ComPPI
LRATD2 TAX1BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFAIP3 TAX1BP1 10435631 11389905 14525934 24234451 25348397 30561431 association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,two hybrid,virotrap ComPPI,HPRD,IntAct
KIF5B TAX1BP1 25348397 N/A physical interaction ComPPI
TRAF6 TAX1BP1 10920205 14525934 17703191 18239685 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
VCP TAX1BP1 25348397 N/A physical interaction ComPPI
GABARAPL2 TAX1BP1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNIP1 TAX1BP1 24234451 25348397 25416956 30561431 association,physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,virotrap ComPPI,IntAct
OPTN TAX1BP1 25348397 N/A physical interaction ComPPI
MAP1LC3B TAX1BP1 25348397 N/A physical interaction ComPPI
TSHZ3 TAX1BP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FOXC2 TAX1BP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF115 TAX1BP1 25348397 N/A physical interaction ComPPI
DSTN TAX1BP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COP1 TAX1BP1 25348397 N/A physical interaction ComPPI
ARHGAP1 TAX1BP1 14525934 14697242 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
UBB TAX1BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBC TAX1BP1 18239685 24234451 25348397 physical association pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBA52 TAX1BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NTRK1 TAX1BP1 25348397 N/A physical interaction ComPPI
TRAF3 TAX1BP1 25348397 N/A physical interaction ComPPI
GABRR1 TAX1BP1 16999686 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CFTR TAX1BP1 25348397 N/A physical interaction ComPPI
SQSTM1 TAX1BP1 25348397 N/A physical interaction ComPPI
STARD13 TAX1BP1 14525934 14697242 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
RAD18 TAX1BP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RABGEF1 TAX1BP1 25348397 N/A physical interaction ComPPI
GABARAP TAX1BP1 25348397 N/A physical interaction ComPPI
ITCH TAX1BP1 25348397 N/A physical interaction ComPPI
CHUK TAX1BP1 21765415 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,protein kinase assay ComPPI,IntAct
TAX1BP1 TBC1D17 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TAX1BP1 RIPK1 14525934 19131965 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TAX1BP1 RNF11 14525934 15231748 19131965 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
TAX1BP1 IKBKE 25348397 N/A physical interaction ComPPI
TAX1BP1 TBK1 25348397 N/A physical interaction ComPPI
TAX1BP1 MYO6 25348397 N/A physical interaction ComPPI
TAX1BP1 CALCOCO2 25348397 N/A physical interaction ComPPI
TAX1BP1 PRKN 25348397 N/A physical interaction ComPPI
TAX1BP1 ORC5 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TAX1BP1 IKBKG 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TAX1BP1 MAP1LC3C 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 LGALS8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 SSX2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 TCEA2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 TSG101 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 FAM189A2 25348397 N/A physical interaction ComPPI
TAX1BP1 DAZAP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 EMILIN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 RAB18 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 FAM168A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 CXXC1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 NMRK1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 LMO3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 MRPL11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 TNIP3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 PLEKHN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 CWF19L2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 REEP4 25348397 N/A physical interaction ComPPI
TAX1BP1 FHL5 25348397 N/A physical interaction ComPPI
TAX1BP1 RNF126 25348397 N/A physical interaction ComPPI
TAX1BP1 HSD17B3 25348397 N/A physical interaction ComPPI
TAX1BP1 CCNQ 25348397 N/A physical interaction ComPPI
TAX1BP1 LDLRAD4 25348397 N/A physical interaction ComPPI
TAX1BP1 MED4 25348397 N/A physical interaction ComPPI
TAX1BP1 RAD54L2 25348397 N/A physical interaction ComPPI
TAX1BP1 HNRNPD 25348397 N/A physical interaction ComPPI
TAX1BP1 UBE2A 25348397 N/A physical interaction ComPPI
TAX1BP1 AGO1 25348397 N/A physical interaction ComPPI
TAX1BP1 GABARAPL1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 KCTD7 25348397 N/A physical interaction ComPPI
TAX1BP1 SLC22A23 25348397 N/A physical interaction ComPPI
TAX1BP1 KDELR1 25348397 N/A physical interaction ComPPI
TAX1BP1 DNAJC11 25348397 N/A physical interaction ComPPI
TAX1BP1 SLC5A12 25348397 N/A physical interaction ComPPI
TAX1BP1 RNF26 25348397 N/A physical interaction ComPPI
TAX1BP1 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
TAX1BP1 NCOA4 25348397 N/A physical interaction ComPPI
TAX1BP1 TBC1D15 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 RAD23B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 L3MBTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 POLR1C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 TSEN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 USP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 SCNM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 TRAF4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 PLEKHB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 UBTFL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 KAT5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 FAM161A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 LITAF 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 IFIH1 24234451 25348397 29251827 association anti bait coimmunoprecipitation ComPPI,IntAct
COG7 TAX1BP1 24234451 25348397 25416956 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
C18ORF25 TAX1BP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPL53 TAX1BP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP1 TAX1BP1 10920205 14525934 24234451 physical association anti tag coimmunoprecipitation,experimental interaction detection HPRD,IntAct
BIRC2 TAX1BP1 24234451 30561431 association virotrap IntAct
TNFAIP3 TAX1BP1 10435631 11389905 18239685 18246070 20185725 21765415 23018911 27898060 N/A N/A OmniPath
TAX1BP1 TNFAIP3 10435631 11389905 18239685 18246070 20185725 21765415 23018911 27898060 stimulant N/A OmniPath
CHUK TAX1BP1 21765415 27898060 stimulant N/A OmniPath
TRAF6 TAX1BP1 10920205 17703191 18239685 18246070 20185725 21765415 21988832 27898060 N/A N/A OmniPath
TAX1BP1 RIPK1 17703191 18239685 18246070 18570872 18621737 19131965 27898060 N/A N/A OmniPath

Visualization










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