GENE：SGSM2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SGSM2 |
| FullNmae | small G protein signaling modulator 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29026 |
| EnsembleID | ENSG00000141258 |
| Uniprot | O43147 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SGSM2 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SGSM2 | GO:0005096,GO:0005096,GO:0005737,GO:0031267,GO:0034499,GO:0042470,GO:0043547,GO:0090630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HIF1A | SGSM2 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | SGSM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SGSM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SGSM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | SGSM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | SGSM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SGSM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000075A608 | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000136174 | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AB32B | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D986D | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043C1C3 | SGSM2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027352D | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D4175 | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004D84DB | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F9738 | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | SGSM2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HNRNPL | SGSM2 | 25348397 | N/A | physical interaction | ComPPI |
| RPS25 | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| EGFR | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| KHDRBS3 | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PTPRN | SGSM2 | 25348397 | N/A | physical interaction | ComPPI |
| MPP1 | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ILF2 | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| CETN1 | SGSM2 | 25348397 | N/A | physical interaction | ComPPI |
| CELSR3 | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| FNBP1L | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PTN | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PNO1 | SGSM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| SGSM2 | AFP | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| SGSM2 | CHD3 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |