GENE:ANK1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | ANK1 |
FullNmae | ankyrin 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:492 |
EnsembleID | ENSG00000029534 |
Uniprot | P16157 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
ANK1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
ANK1 | GO:0005198,GO:0005200,GO:0005515,GO:0005829,GO:0005856,GO:0005886,GO:0005886,GO:0005886,GO:0006887,GO:0006888,GO:0007010,GO:0007165,GO:0008093,GO:0008093,GO:0008093,GO:0009898,GO:0010638,GO:0014731,GO:0016323,GO:0016529,GO:0019899,GO:0019899,GO:0019903,GO:0030018,GO:0030507,GO:0030507,GO:0030507,GO:0030507,GO:0030673,GO:0031430,GO:0042383,GO:0043005,GO:0044325,GO:0045199,GO:0045211,GO:0051117,GO:0072659,GO:0072659,GO:0170014 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
ANK1 | hsa:286 | path:hsa05205 | Proteoglycans in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | ANK1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
E2F4 | ANK1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | ANK1 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA1 | ANK1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | ANK1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | ANK1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
TP73 | ANK1 | 21245298 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
FOXP3 | ANK1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
PRDM14 | ANK1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | ANK1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000284586 | ANK1 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000072B4C8 | ANK1 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000034B6F5 | ANK1 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00001925C1 | ANK1 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000075AB35 | ANK1 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000BD6DC | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000009EA8F | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075C3F6 | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000ECE9C | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004E02F2 | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000004BACE | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000001A7A | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000036AFF1 | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000A9FB9 | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000032835F | ANK1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000023133F | ANK1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005194EC | ANK1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000070B1D | ANK1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001B9F58 | ANK1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000039D790 | ANK1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003D8730 | ANK1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
EMD | ANK1 | 25348397 | N/A | two hybrid | ComPPI |
KCTD6 | ANK1 | 25348397 | N/A | physical interaction | ComPPI |
CD44 | ANK1 | 14525934 15051494 25348397 27898060 7505012 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
TIAM1 | ANK1 | 10893266 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
NELFB | ANK1 | 25348397 | N/A | physical interaction | ComPPI |
TTN | ANK1 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
CUL3 | ANK1 | 25348397 | N/A | physical interaction | ComPPI |
L1CAM | ANK1 | 11222639 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
RYR1 | ANK1 | 25348397 | N/A | physical interaction | ComPPI |
SPTAN1 | ANK1 | 14525934 2141335 25348397 27898060 2970468 2971657 492324 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
EPB42 | ANK1 | 14525934 25348397 2968981 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
ANK1 | RHAG | 12719424 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
ANK1 | SLC4A1 | 14525934 25348397 27898060 6449514 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
ANK1 | SPTA1 | 15929114 25348397 27898060 2971657 | N/A | physical interaction | ComPPI,OmniPath |
ANK1 | SPTBN1 | 25348397 | N/A | physical interaction | ComPPI |
ANK1 | TGFBR1 | 25348397 | N/A | physical interaction | ComPPI |
ANK1 | HSPB1 | 24234451 25277244 25348397 | physical association | reverse ras recruitment system,physical interaction | ComPPI,IntAct |
ANK1 | PIKFYVE | 25348397 | N/A | physical interaction | ComPPI |
ANK1 | PDS5B | 25348397 | N/A | physical interaction | ComPPI |
NBPF3 | ANK1 | 14525934 27898060 9587054 | N/A | experimental interaction detection | HPRD,OmniPath |
ANK1 | ITPR3 | 14525934 15051494 27898060 8385102 | N/A | experimental interaction detection | HPRD,OmniPath |
CSNK1G1 | ANK1 | 27898060 2933395 | inhibition | N/A | OmniPath |