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GENE：EEF1E1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EEF1E1
FullNmae eukaryotic translation elongation factor 1 epsilon 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3212
EnsembleID ENSG00000124802
Uniprot O43324

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EEF1E1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EEF1E1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EEF1E1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EEF1E1 GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006412,GO:0008285,GO:0017101,GO:0017101,GO:0043065,GO:0043517,GO:1990830,GO:2000774,GO:2001235

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EEF1E1 ARF6 20005715 interaction type N/A PSP
EEF1E1 ATM 20005715 interaction type N/A PSP
EEF1E1 ATR 20005715 interaction type N/A PSP
EEF1E1 ATM 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR EEF1E1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 EEF1E1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 EEF1E1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 EEF1E1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 EEF1E1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 EEF1E1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EEF1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 EEF1E1 19136465 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000324096 EEF1E1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003AA845 EEF1E1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 EEF1E1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB EEF1E1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B EEF1E1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D EEF1E1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC EEF1E1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AIMP2 EEF1E1 25348397 N/A physical interaction ComPPI
EIF1B EEF1E1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KEAP1 EEF1E1 25348397 N/A physical interaction ComPPI
MCM2 EEF1E1 25348397 N/A physical interaction ComPPI
STRN EEF1E1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATR EEF1E1 14525934 15680327 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JUN EEF1E1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4G1 EEF1E1 25348397 N/A physical interaction ComPPI
BLK EEF1E1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PKN2 EEF1E1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLD EEF1E1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
IQGAP1 EEF1E1 25348397 N/A physical interaction ComPPI
VDAC1 EEF1E1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF2S1 EEF1E1 25348397 N/A physical interaction ComPPI
PDHA1 EEF1E1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SDCBP EEF1E1 25348397 N/A physical interaction ComPPI
EPRS1 EEF1E1 25348397 N/A physical interaction ComPPI
RARS1 EEF1E1 25348397 N/A physical interaction ComPPI
ATM EEF1E1 14525934 15680327 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
QARS1 EEF1E1 25348397 N/A physical interaction ComPPI
HUWE1 EEF1E1 25348397 N/A physical interaction ComPPI
ARF6 EEF1E1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPLP0 EEF1E1 25348397 N/A physical interaction ComPPI
HNRNPA2B1 EEF1E1 25348397 N/A physical interaction ComPPI
RPL7A EEF1E1 25348397 N/A physical interaction ComPPI
RAF1 EEF1E1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VCAM1 EEF1E1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
ITGA4 EEF1E1 25348397 N/A physical interaction ComPPI
EIF2S3 EEF1E1 25348397 N/A physical interaction ComPPI
UBA1 EEF1E1 25348397 N/A physical interaction ComPPI
MARS1 EEF1E1 24212136 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
IARS1 EEF1E1 25348397 N/A physical interaction ComPPI
TWF1 EEF1E1 25348397 N/A physical interaction ComPPI
KARS1 EEF1E1 25348397 N/A physical interaction ComPPI
RPL23A EEF1E1 25348397 N/A physical interaction ComPPI
RPL13 EEF1E1 25348397 N/A physical interaction ComPPI
ATP6V1A EEF1E1 25348397 N/A physical interaction ComPPI
DNAJA1 EEF1E1 25348397 N/A physical interaction ComPPI
CALCOCO2 EEF1E1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MED4 EEF1E1 25348397 N/A physical interaction ComPPI
DARS1 EEF1E1 25348397 N/A physical interaction ComPPI
EEF1E1 AIMP1 25348397 N/A physical interaction ComPPI
EEF1E1 RPL15 25348397 N/A physical interaction ComPPI
EEF1E1 RPL18 25348397 N/A physical interaction ComPPI
EEF1E1 RPLP0P6 25348397 N/A physical interaction ComPPI
EEF1E1 EIF2S3B 25348397 N/A physical interaction ComPPI
EEF1E1 CCAR2 25348397 N/A physical interaction ComPPI
EEF1E1 RPL21 25348397 N/A physical interaction ComPPI
EEF1E1 RPL24 25348397 N/A physical interaction ComPPI
EEF1E1 RPL26 25348397 N/A physical interaction ComPPI
EEF1E1 RPL27A 25348397 N/A physical interaction ComPPI
EEF1E1 RPL36 25348397 N/A physical interaction ComPPI
EEF1E1 NAT9 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EEF1E1 CIAPIN1 25348397 N/A physical interaction ComPPI
EEF1E1 LARS1 25348397 N/A physical interaction ComPPI
EEF1E1 RNASEH2C 25348397 N/A physical interaction ComPPI
EEF1E1 CHAMP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EEF1E1 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EEF1E1 HSD17B10 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EEF1E1 SOAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ATP6V1B2 EEF1E1 25348397 N/A physical interaction ComPPI
L1TD1 EEF1E1 24234451 25702638 association anti bait coimmunoprecipitation IntAct
EEF1E1 ATR 15680327 18066086 27898060 stimulant N/A OmniPath

Visualization










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