GENE:EFNB3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | EFNB3 |
| FullNmae | ephrin B3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3228 |
| EnsembleID | ENSG00000108947 |
| Uniprot | Q15768 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| EFNB3 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| EFNB3 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| EFNB3 | GO:0001618,GO:0005005,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0007267,GO:0007399,GO:0007411,GO:0007628,GO:0016198,GO:0031295,GO:0042734,GO:0046718,GO:0046875,GO:0046875,GO:0046875,GO:0048013,GO:0048013,GO:0050771,GO:0050806,GO:0098686,GO:0098839,GO:0098978,GO:0099557,GO:1905608 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| EFNB3 | hsa:1949 | path:hsa04360 | Axon guidance - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | EFNB3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | EFNB3 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CTCF | EFNB3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | EFNB3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | EFNB3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYCN | EFNB3 | 19885598 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| EFNB3 | EPHA4 | 25361965 | interaction type | N/A | PTMCode2 |
| EPHA4 | EFNB3 | 25361965 | interaction type | N/A | PTMCode2 |
| EFNB3 | RHBDL2 | 25361965 | interaction type | N/A | PTMCode2 |
| RHBDL2 | EFNB3 | 25361965 | interaction type | N/A | PTMCode2 |
| EFNB3 | EPHB6 | 25361965 | interaction type | N/A | PTMCode2 |
| EPHB6 | EFNB3 | 25361965 | interaction type | N/A | PTMCode2 |
| EPHA8 | EFNB3 | 25361965 | interaction type | N/A | PTMCode2 |
| EFNB3 | EPHA8 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YWHAZ | EFNB3 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| TUBA4A | EFNB3 | 25348397 | N/A | physical interaction | ComPPI |
| AATF | EFNB3 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| DLG1 | EFNB3 | 25348397 | N/A | physical interaction | ComPPI |
| EPHA4 | EFNB3 | 12383247 14525934 23812375 24234451 25348397 9484836 | N/A | experimental interaction detection,x-ray crystallography,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| ELOC | EFNB3 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| RGS3 | EFNB3 | 25348397 | N/A | physical interaction | ComPPI |
| EPHB3 | EFNB3 | 14525934 25348397 9484836 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CDYL | EFNB3 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | RHBDL2 | 14525934 15047175 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| EFNB3 | P2RX7 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| EFNB3 | HLA-DPA1 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | TBC1D22A | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | MPP7 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | TNFSF8 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | FAM221B | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | PKN3 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | TCAF2 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | RTEL1 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | PLCD3 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | DENND11 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | TUBB8 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | MC1R | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | TUBB3 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | TRIM11 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | IGSF8 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | DENND6A | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | RAD51C | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | PRKCSH | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | LGALS1 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | EVI5L | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | THUMPD3 | 25348397 | N/A | physical interaction | ComPPI |
| EFNB3 | EFNB3 | 10197531 14525934 | N/A | experimental interaction detection,two hybrid | HPRD |
| EFNB3 | EPHA4 | 12383247 23812375 27898060 9330863 9484836 | stimulant | N/A | OmniPath |
| EPHB6 | EFNB3 | 15114347 27898060 | N/A | N/A | OmniPath |
| EFNB3 | EPHB3 | 27898060 9330863 9484836 | stimulant | N/A | OmniPath |
| EFNB3 | EPHB4 | 27898060 8755474 | N/A | N/A | OmniPath |
