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GENE：NUDT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUDT2
FullNmae nudix hydrolase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8049
EnsembleID ENSG00000164978
Uniprot P50583

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUDT2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NUDT2 GO:0004081,GO:0004081,GO:0004081,GO:0005515,GO:0005525,GO:0005759,GO:0006139,GO:0006167,GO:0006754,GO:0006915,GO:0008803,GO:0034599

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NUDT2 hsa:318 path:hsa00230 Purine metabolism - Homo sapiens (human)
NUDT2 hsa:318 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
NUDT2 hsa:318 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GAPDH NUDT2 23180781 7626640 physical association molecular weight estimation by autoradiography InnateDB
NUDT2 MCM6 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 NUDT2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 NUDT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NUDT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NUDT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NUDT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 NUDT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NUDT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NUDT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE NUDT2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 NUDT2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PLEKHF2 NUDT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MCM6 NUDT2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NUDT2 ESR2 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
DDIT4L NUDT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GAPDH NUDT2 27898060 7626640 N/A N/A OmniPath

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